Search Results - "Hao, Marlene M"
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Regional complexity in enteric neuron wiring reflects diversity of motility patterns in the mouse large intestine
Published in eLife (12-02-2019)“…The enteric nervous system controls a variety of gastrointestinal functions including intestinal motility. The minimal neuronal circuit necessary to direct…”
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Structurally defined signaling in neuro‐glia units in the enteric nervous system
Published in Glia (01-06-2019)“…Coordination of gastrointestinal function relies on joint efforts of enteric neurons and glia, whose crosstalk is vital for the integration of their activity…”
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Organelle mapping in dendrites of human iPSC-derived neurons reveals dynamic functional dendritic Golgi structures
Published in Cell reports (Cambridge) (25-07-2023)“…Secretory pathways within dendrites of neurons have been proposed for local transport of newly synthesized proteins. However, little is known about the…”
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Development of enteric neuron diversity
Published in Journal of cellular and molecular medicine (01-07-2009)“…• Neuronal diversity in the adult enteric nervous system (ENS) • Developmental appearance and birthdating of enteric neuron subtypes and glial cells ‐ …”
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From diversity to disease: unravelling the role of enteric glial cells
Published in Frontiers in immunology (18-06-2024)“…Enteric glial cells (EGCs) are an essential component of the enteric nervous system (ENS) and play key roles in gastrointestinal development, homeostasis, and…”
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Development of myenteric cholinergic neurons in ChAT-Cre;R26R-YFP mice
Published in Journal of comparative neurology (1911) (01-10-2013)“…ABSTRACT Cholinergic neurons are the major excitatory neurons of the enteric nervous system (ENS), and include intrinsic sensory neurons, interneurons, and…”
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Hirschsprung disease: a developmental disorder of the enteric nervous system
Published in Wiley interdisciplinary reviews. Developmental biology (01-01-2013)“…Hirschsprung disease (HSCR), which is also called congenital megacolon or intestinal aganglionosis, is characterized by an absence of enteric (intrinsic)…”
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Development, Diversity, and Neurogenic Capacity of Enteric Glia
Published in Frontiers in cell and developmental biology (17-01-2022)“…Enteric glia are a fascinating population of cells. Initially identified in the gut wall as the "support" cells of the enteric nervous system, studies over the…”
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Imaging neuron-glia interactions in the enteric nervous system
Published in Frontiers in cellular neuroscience (21-10-2013)“…The enteric nervous system (ENS) is a network of neurons and glia within the wall of the gastrointestinal tract that is able to control many aspects of…”
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Group I Metabotropic Glutamate Receptors Modulate Motility and Enteric Neural Activity in the Mouse Colon
Published in Biomolecules (Basel, Switzerland) (09-01-2023)“…Glutamate is the major excitatory neurotransmitter in the central nervous system, and there is evidence that Group-I metabotropic glutamate receptors (mGlu1…”
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Colonizing while migrating: how do individual enteric neural crest cells behave?
Published in BMC biology (26-03-2014)“…Directed cell migration is essential for normal development. In most of the migratory cell populations that have been analyzed in detail to date, all of the…”
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The emergence of neural activity and its role in the development of the enteric nervous system
Published in Developmental biology (01-10-2013)“…The enteric nervous system (ENS) is a vital part of the autonomic nervous system that regulates many gastrointestinal functions, including motility and…”
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A Novel Method for Identifying the Transition Zone in Long-Segment Hirschsprung Disease: Investigating the Muscle Unit to Ganglion Ratio
Published in Biomolecules (Basel, Switzerland) (10-08-2022)“…Hirschsprung disease (HSCR) is characterised by the absence of enteric ganglia along variable lengths of the distal bowel. Current gold standard treatment…”
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14
Optical Tools to Investigate Cellular Activity in the Intestinal Wall
Published in Journal of neurogastroenterology and motility (01-07-2015)“…Live imaging has become an essential tool to investigate the coordinated activity and output of cellular networks. Within the last decade, 2 Nobel prizes have…”
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Early emergence of neural activity in the developing mouse enteric nervous system
Published in The Journal of neuroscience (26-10-2011)“…Neurons of the enteric nervous system (ENS) arise from neural crest cells that migrate into and along the developing gastrointestinal tract. A subpopulation of…”
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Development of Neural Activity in the Enteric Nervous System: Similarities and Differences to Other Parts of the Nervous System
Published in Advances in experimental medicine and biology (01-01-2016)“…All the neurons and glia of the enteric nervous system (ENS) arise from neural crest-derived cells that migrate into the gastrointestinal (GI) tract during…”
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Early development of electrical excitability in the mouse enteric nervous system
Published in The Journal of neuroscience (08-08-2012)“…Neural activity is integral to the development of the enteric nervous system (ENS). A subpopulation of neural crest-derived cells expresses pan-neuronal…”
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The many means of conversation between the brain and the gut
Published in Nature reviews. Gastroenterology & hepatology (01-02-2023)“…Various pathways enable communication between the gut and brain, and this communication influences physiology and behaviour. Studies published in 2022…”
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Optogenetic and chemogenetic techniques for neurogastroenterology
Published in Nature reviews. Gastroenterology & hepatology (01-01-2018)“…Key Points Optogenetic actuators are light-driven proteins able to perturb electrochemical signals, whereas optogenetic indicators are capable of reporting…”
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Simultaneous whole-cell patch-clamp and calcium imaging on myenteric neurons
Published in American journal of physiology: Gastrointestinal and liver physiology (01-10-2022)“…Live calcium imaging is often used as a proxy for electrophysiological measurements and has been a valuable tool that allows simultaneous analysis of neuronal…”
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