Search Results - "Hao, Luke"
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Human bone perivascular niche-on-a-chip for studying metastatic colonization
Published in Proceedings of the National Academy of Sciences - PNAS (06-02-2018)“…Eight out of 10 breast cancer patients die within 5 years after the primary tumor has spread to the bones. Tumor cells disseminated from the breast roam the…”
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Integrated human organ-on-a-chip model for predictive studies of anti-tumor drug efficacy and cardiac safety
Published in Lab on a chip (24-11-2020)“…Traditional drug screening models are often unable to faithfully recapitulate human physiology in health and disease, motivating the development of…”
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Two-stage approach to intracranial hemorrhage segmentation from head CT images
Published in IEEE access (01-01-2024)“…Intracranial hemorrhage (ICH) is an emergency and a potentially life-threatening condition. Automated segmentation of ICH from head CT images can provide…”
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The Manipulation and Alignment of Silicon Carbide Whiskers for Gallium Nitride Epitaxial Growth
Published in Journal of the American Ceramic Society (01-10-2014)“…As a substrate candidate for low‐cost III‐nitride thin film growth, 3C–SiC whiskers are employed and manipulated in this work. The alignment of the whiskers is…”
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Hemiepiphysiodesis is a potentially effective surgical management for skeletally immature patients with patellofemoral instability associated with isolated genu valgum
Published in Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA (01-03-2019)“…Purpose Genu valgum is one of the well-known predisposing factors for patellofemoral instability. The study aims to investigate the outcomes of isolated…”
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Homologous recombination repair deficiency as a therapeutic target in sarcoma
Published in Seminars in oncology (01-12-2020)“…Sarcoma is a rare cancer arising from soft tissue and bone and consists of more than 50 distinct subtypes. There is an increasing emphasis on understanding the…”
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Abstract PO-035: A novel bioengineered model of osteosarcoma recapitulates critical tumor phenotypes within a native bone microenvironment
Published in Cancer research (Chicago, Ill.) (01-11-2020)“…Abstract Traditional in-vitro models of solid bone tumors used in basic and preclinical research are unable to faithfully recapitulate human physiology…”
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Exclusion of PD-1 from the immune synapse: A novel strategy to modulate T cell function
Published in Molecular Therapy: Oncology (19-09-2024)“…Targeting immune checkpoint receptors on T cells is a common cancer treatment strategy. Frequently, this is accomplished through antibodies targeting the…”
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Combination of tibial tubercle transfer, medial patellofemoral ligament reconstruction, trochleoplasty and lateral release for patellofemoral instability provides good middle- to long-term outcomes in adolescents
Published in European journal of orthopaedic surgery & traumatology (01-04-2024)“…Purpose There are limited studies that have reported the middle- to long-term outcomes of combined procedures consisting of more than two procedures for…”
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