Search Results - "Hao, Jingya"
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The noncovalent dimerization of a G-quadruplex/hemin DNAzyme improves its biocatalytic properties
Published in Chemical science (Cambridge) (12-08-2020)“…While many protein enzymes exert their functions through multimerization, which improves both selectivity and activity, this has not yet been demonstrated for…”
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2
Controllable stereoinversion in DNA-catalyzed olefin cyclopropanation via cofactor modification
Published in Chemical science (Cambridge) (11-05-2021)“…The assembly of DNA with metal-complex cofactors can form promising biocatalysts for asymmetric reactions, although catalytic performance is typically limited…”
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3
Loop permutation affects the topology and stability of G-quadruplexes
Published in Nucleic acids research (12-10-2018)“…Abstract G-quadruplexes are unusual DNA and RNA secondary structures ubiquitous in a variety of organisms including vertebrates, plants, viruses and bacteria…”
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Fluorescence Spectroscopic Insight into the Supramolecular Interactions in DNA‐Based Enantioselective Sulfoxidation
Published in Chembiochem : a European journal of chemical biology (18-10-2018)“…Interactions of copper(II)–bipyridine cofactors and thioanisole substrate with human telomeric G‐quadruplex DNA were studied by UV/Vis absorption, circular…”
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5
Terpyridine-Cu(ii) targeting human telomeric DNA to produce highly stereospecific G-quadruplex DNA metalloenzyme
Published in Chemical science (Cambridge) (01-10-2015)“…The cofactors commonly involved in natural enzymes have provided the inspiration for numerous advances in the creation of artificial metalloenzymes…”
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6
Higher-order human telomeric G-quadruplex DNA metalloenzyme catalyzed Diels-Alder reaction: an unexpected inversion of enantioselectivity modulated by K(+) and NH4(+) ions
Published in Chemical communications (Cambridge, England) (28-08-2015)“…We report that K(+) and NH4(+) present different allosteric activation for higher-order human telomeric G-quadruplex DNA metalloenzyme. The obtained major endo…”
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7
Highly Selective Detection of K+ Based on a Dimerized G‑Quadruplex DNAzyme
Published in Analytical chemistry (Washington) (11-05-2021)“…Potassium ion (K+) plays a crucial role in biological systems, such as maintaining cellular processes and causing diseases. However, specifically, the…”
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Cationic Porphyrin-Mediated G‑Quadruplex DNA Oxidative Damage: Regulated by the Initial Interplay between DNA and TMPyP4
Published in Biochemistry (Easton) (07-12-2021)“…G-quadruplex (G4) ligand-induced DNA damage has been involved in many physiological functions of cells. Herein, cationic porphyrin (TMPyP4)-mediated DNA…”
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9
Enantioselective Olefin Cyclopropanation with G‑Quadruplex DNA-Based Biocatalysts
Published in ACS catalysis (05-06-2020)“…Developing high-performance DNA-based biocatalysts for desired stereoselective syntheses remains a formidable challenge. Here, we report promising DNA-based…”
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Probing the interaction of copper cofactor and azachalcone substrate with G-quadruplex of DNA based Diels-Alderase by site-specific fluorescence quenching titration
Published in Biochimie (01-03-2018)“…DNAzymes have been widely used in biosensors, asymmetric synthesis and pharmaceuticals. Typically, metal cofactor and substrate interact with DNA by…”
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Terpyridine-Cu(ii) targeting human telomeric DNA to produce highly stereospecific G-quadruplex DNA metalloenzymeElectronic supplementary information (ESI) available: Experimental details, ESI figures and tables, 1H NMR spectra and HPLC traces. See DOI: 10.1039/c5sc01381j
Published 14-09-2015“…The cofactors commonly involved in natural enzymes have provided the inspiration for numerous advances in the creation of artificial metalloenzymes…”
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12
Terpyridine–Cu(ii) targeting human telomeric DNA to produce highly stereospecific G-quadruplex DNA metalloenzyme† †Electronic supplementary information (ESI) available: Experimental details, ESI figures and tables, 1H NMR spectra and HPLC traces. See DOI: 10.1039/c5sc01381j
Published in Chemical science (Cambridge) (24-06-2015)“…A highly stereospecific G-quadruplex DNA metalloenzyme was found by exploring the G-quadruplex targeting ligand pool. The cofactors commonly involved in…”
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13
Infrared/laser multi-sensor fusion and tracking based on the multi-scale model
Published in Infrared physics & technology (01-03-2016)“…The state estimation problem of targets detected by infrared/laser composite detection system with different sampling rates was studied in this paper. An…”
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14
Controllable stereoinversion in DNA-catalyzed olefin cyclopropanation cofactor modification
Published in Chemical science (Cambridge) (09-06-2021)“…The assembly of DNA with metal-complex cofactors can form promising biocatalysts for asymmetric reactions, although catalytic performance is typically limited…”
Get full text
Journal Article