Search Results - "Hao, Fengjin"

Bulbocodin D ameliorate cognitive impairment in APP/PS1 transgenic mice by modulating amyloid-beta burden, oxidative status and neuroinflammation by Hao, Fengjin, Feng, Yueqin

“…Rationale Amyloid β peptide (Aβ) triggers a series of pathological events including microglial activation, oxidative stress, and inflammation-causing neuronal…”
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GSK2126458 has the potential to inhibit the proliferation of pancreatic cancer uncovered by bioinformatics analysis and pharmacological experiments by Feng, Yueqin, Jiang, Yuguan, Hao, Fengjin

“…Abstract Background Pancreatic cancer is one of the most serious digestive malignancies. At present, there is an extreme lack of effective strategies in…”
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Hansenia weberbaueriana (Fedde ex H.Wolff) Pimenov & Kljuykov Extract Suppresses Proliferation of HepG2 Cells via the PTEN-PI3K-AKT Pathway Uncovered by Integrating Network Pharmacology and Iin Vitro Experiments by Feng, Yueqin, Hao, Fengjin

“…Previous studies have shown that (Fedde ex H.Wolff) Pimenov & Kljuykov extracts (HWEs) have antitumor activity, but their mechanism is still unclear. In this…”
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Effects of Central Loop Length and Metal Ions on the Thermal Stability of G-Quadruplexes by Hao, Fengjin, Ma, Yushu, Guan, Yifu

“…The central loop of G-quadruplex molecular beacons is a key element to sense target DNA or RNA sequences. In this study, circular dichroism spectroscopy (CD),…”
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A Novel Botulinum Toxin TAT-EGFP-HCS Fusion Protein Capable of Specific Delivery Through the Blood-brain Barrier to the Central Nervous System by Hao, Fengjin, Feng, Yueqin, Guan, Yifu

“…Botulinum toxin has many applications in the treatment of central diseases, as biological macromolecules, it is difficult to pass through the blood-brain…”
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Effects of the TAT Peptide Orientation and Relative Location on the Protein Transduction Efficiency by Guo, Qingguo, Zhao, Guojie, Hao, Fengjin, Guan, Yifu

“…To understand the protein transduction domain (PTD)‐mediated protein transduction behavior and to explore its potential in delivering biopharmaceutic drugs, we…”
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Cannabidiol (CBD) enhanced the hippocampal immune response and autophagy of APP/PS1 Alzheimer's mice uncovered by RNA-seq by Hao, Fengjin, Feng, Yueqin

“…Alzheimer's disease (AD) is a central nervous system disease characterized by dementia, which has now become a major threat to global health. Cannabidiol (CBD)…”
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Advances in natural polysaccharides in Alzheimer's disease and Parkinson's disease: Insights from the brain-gut axis by Feng, Yueqin, Hao, Fengjin

“…Due to the rapid increase in aging population, there has been a rise in cases of neurodegenerative diseases (NDs), which is a major challenge for human health…”
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Biological evaluation of naturally occurring bulbocodin D as a potential multi-target agent for Alzheimer’s disease by Hao, Fengjin, Feng, Yueqin

“…•Bulbocodin D can reverse the apoptosis of SY5Y cells induced by H2O2.•Bulbocodin D can inhibit the cytokines of BV2 cells induced by LPS.•Bulbocodin D had a…”
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The role of autophagy and Beclin-1 in radiotherapy-induced apoptosis in thyroid carcinoma cells by Gao, Peng, Hao, Fengjin, Dong, Xiu, Qiu, Yan

“…Thyroid cancer (TC), especially primary squamous cell carcinoma (SCC), is an aggressive malignant tumor which usually resists radiotherapy (RT). We wanted to…”
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ROS mediated radiotherapy-induced protective autophagy in thyroid cancer by Gao, Peng, Hao, Fengjin, Zhang, Qi, Qiu, Yan

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Adiponectin exhibits proliferative and anti-apoptotic effects on ovarian cancer cells via PI3K/Akt and Raf/MEK/ERK pathways by Feng, Yueqin, Hao, Fengjin, Wan, Weina, Wang, Xuemei

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A novel G-quadruplex motif in the Human MET promoter region by Yan, Jing, Zhao, Deming, Dong, Liping, Pan, Shuang, Hao, Fengjin, Guan, Yifu

“…It is known that the guanine-rich strands in proto-oncogene promoters can fold into G-quadruplex structures to regulate gene expression. An intramolecular…”
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