Search Results - "Hao, Chunfang"
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Clinicopathological Features and Prognosis of Gastrointestinal Metastases From Breast Carcinoma: A Clinicopathological Study of 22 Patients
Published in International journal of surgical pathology (01-09-2023)“…Background. Breast carcinoma is the most common malignancy in women. Gastrointestinal metastasis is rarely found or diagnosed in patients with breast cancer…”
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Real‐world data for the renal safety of abemaciclib combined with bisphosphonate in HR+/HER2− advanced breast cancer
Published in Thoracic cancer (01-01-2023)“…Objective Our study evaluated the renal safety of abemaciclib plus endocrine therapy (ET) with bisphosphonate as a treatment option for hormone receptor…”
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3
The changes of subtype markers between first and second primary breast cancers
Published in Cancer medicine (Malden, MA) (01-06-2023)“…Background Previous studies investigated the changes of subtype markers [estrogen receptor (ER), progesterone receptor (PR), and human epidermal growth factor…”
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Cytokine levels and pathological characteristics of a patient with severe coronavirus disease 2019: a case report
Published in Chinese medical journal (05-01-2022)“…Laboratory tests revealed that the IL-6 and IL-10 levels were increased (345.51 and 44.77 pg/mL, respectively). [...]CD4+ T cell count was 147 cells/μL, and…”
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5
Establishing extended pluripotent stem cells from human urine cells
Published in Cell & bioscience (16-05-2023)“…Extended pluripotent stem cells (EPSCs) can contribute to both embryonic and trophectoderm-derived extraembryonic tissues. Therefore, EPSCs have great…”
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Comparisons of clinical characteristics, prognosis, epidemiological factors, and genetic susceptibility between HER2‐low and HER2‐zero breast cancer among Chinese females
Published in Cancer medicine (Malden, MA) (01-07-2023)“…Background Traditional human epidermal growth factor receptor 2 (HER2)‐negative breast cancer (BC) is recommended to be divided into HER2‐low and HER2‐zero…”
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Gene Mutations Associated With Clinical Characteristics in the Tumors of Patients With Breast Cancer
Published in Frontiers in oncology (14-04-2022)“…Clinical characteristics including estrogen receptor (ER), progesterone receptor (PR), and human epidermal growth factor 2 (HER2) are important biomarkers in…”
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Stimulatory Cross-talk between NFAT3 and Estrogen Receptor in Breast Cancer Cells
Published in The Journal of biological chemistry (30-12-2005)“…Estrogen receptors (ERα and ERβ) are ligand-regulated transcription factors that play critical roles in the development and progression of breast cancer by…”
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SNX16 negatively regulates the migration and tumorigenesis of MCF-7 cells
Published in Cell regeneration (30-04-2013)“…Sorting nexins are a large family of proteins that are associated with various components of the endosome system and they play many roles in processes such as…”
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10
PI3K/AKT/mTOR inhibitors for hormone receptor-positive advanced breast cancer
Published in Cancer treatment reviews (01-11-2024)Get full text
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11
CDK4/6 inhibitors combined with fulvestrant for HR+/HER2− advanced breast cancer
Published in Translational breast cancer research (30-04-2022)Get full text
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12
T-DM1 in Chinese patients with Her2-positive metastatic breast cancer: A multi-center, retrospective, real world study
Published in Journal of clinical oncology (01-06-2024)“…e13026 Background: In the pivotal EMILIA and THRESA study, the proportion of Chinese patients in the clinical trials was very low (17% of Asian patients, 87…”
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Efficacy and safety of pyrotinib combined with trastuzumab emtansine (T-DM1) for patients with advanced HER2-positive breast cancer (BC): A single-arm phase II trial
Published in Journal of clinical oncology (01-06-2024)“…e13005 Background: The Chinese Society of Clinical Oncology Guidelines recommended the pyrotinib plus capecitabine regimen as the standard of care for patients…”
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14
Pyrotinib plus capecitabine for patients with human epidermal growth factor receptor 2-positive breast cancer and brain metastases (PERMEATE): a multicentre, single-arm, two-cohort, phase 2 trial
Published in The lancet oncology (01-03-2022)“…Patients with HER2-positive metastatic breast cancer have a high risk of developing brain metastases. Efficacious treatment options are scarce. We investigated…”
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Pyrotinib in combination with metronomic oral vinorelbine in patients with HER2-positive advanced breast cancer who had failed prior trastuzumab-based therapy: A single-center, single-arm, prospective phase 2 study
Published in Journal of clinical oncology (01-06-2022)“…1033 Background: In 15% to 30% of breast cancers, human epidermal growth factor receptor 2 (HER2) is overexpressed, this is related to aggressive disease and…”
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Pyrotinib plus capecitabine for patients with HER2-positive metastatic breast cancer and brain metastases: 3-year follow-up results from the phase 2 PERMEATE trial
Published in Journal of clinical oncology (01-06-2023)“…1048 Background: HER2-positive metastatic breast cancer has a high risk of brain metastases, leading to poor survival. Our phase 2 PERMEATE trial (NCT03691051)…”
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A phase 3, multicenter, open, randomized controlled clinical study of gemcitabine plus capecitabine versus gemcitabine plus carboplatin in the first-line treatment for advanced triple-negative breast cancer
Published in Journal of clinical oncology (01-06-2022)“…1077 Background: Gemcitabine plus capecitabine (GX) regimen is still lack of phase Ⅲ clinical trial evidence for the first-line treatment of advanced…”
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18
Aberrant Regulation of RAD51 Promotes Resistance of Neoadjuvant Endocrine Therapy in ER-positive Breast Cancer
Published in Scientific reports (10-09-2019)“…Breast cancer is one of the most common malignant cancers affecting females. Estrogen receptor (ER)-positive breast cancer is responsive to endocrine therapy…”
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Pyrotinib plus capecitabine for HER2-positive metastatic breast cancer patients with brain metastases (PERMEATE): A multicenter, single-arm phase II study
Published in Journal of clinical oncology (20-05-2021)“…Abstract only 1037 Background: HER2-positive metastatic breast cancer (BC) has a high risk of brain metastases (BM), leading to poor survival. Small molecule…”
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20
Combination Therapy of Pyrotinib and Metronomic Vinorelbine in HER2+ Advanced Breast Cancer After Trastuzumab Failure (PROVE): A Prospective Phase 2 Study
Published in Cancer research and treatment (09-08-2024)“…Approximately 50-74% of patients with metastatic HER2-positive breast cancer do not respond to trastuzumab, with 75% of treated patients experiencing disease…”
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