Search Results - "Hao, Chuanming"
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Roxadustat Treatment for Anemia in Patients Undergoing Long-Term Dialysis
Published in The New England journal of medicine (12-09-2019)“…This randomized, phase 3 trial compared the effectiveness of roxadustat, an oral hypoxia-inducible factor prolyl hydroxylase inhibitor, with epoetin alfa in…”
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Roxadustat for Anemia in Patients with Kidney Disease Not Receiving Dialysis
Published in The New England journal of medicine (12-09-2019)“…This phase 3, randomized trial in China compared the efficacy and safety of roxadustat, an oral hypoxia-inducible factor prolyl hydroxylase inhibitor, with…”
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3
Risk stratification for infection during immunosuppressive therapy in patients with lupus nephritis: A nested case-control study
Published in Lupus (01-07-2024)“…Background The current prediction models for the risk of infection during immunosuppressive treatment for lupus nephritis (LN) lack a prediction time window…”
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Phase 2 studies of oral hypoxia-inducible factor prolyl hydroxylase inhibitor FG-4592 for treatment of anemia in China
Published in Nephrology, dialysis, transplantation (01-08-2017)“…FG-4592 (roxadustat) is an oral hypoxia-inducible factor (HIF) prolyl hydroxylase inhibitor (HIF-PHI) promoting coordinated erythropoiesis through the…”
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Risk of non-fatal cardiovascular diseases in early-onset versus late-onset type 2 diabetes in China: a cross-sectional study
Published in The lancet. Diabetes & endocrinology (01-02-2016)“…Summary Background The age of onset of type 2 diabetes is decreasing. Because non-Chinese patients with early-onset type 2 diabetes (defined here as diagnosis…”
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Primacy of the 3B Approach to Control Risk Factors for Cardiovascular Disease in Type 2 Diabetes Patients
Published in The American journal of medicine (01-10-2013)“…Abstract Background Individually, diabetes mellitus, hypertension, and dyslipidemia have been shown to increase the risk of cardiovascular disease. While…”
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Tenascin C: A Potential Biomarker for Predicting the Severity of Coronary Atherosclerosis
Published in Journal of Atherosclerosis and Thrombosis (01-01-2019)“…Aims: Coronary artery disease (CAD) is the leading cause of mortality and morbidity worldwide and one of the greatest threats to public health. Tenascin C…”
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Unraveling the nexus of NAD+ metabolism and diabetic kidney disease: insights from murine models and human data
Published in Frontiers in endocrinology (Lausanne) (21-05-2024)“…Nicotinamide adenine dinucleotide (NAD+) is a critical coenzyme involved in kidney disease, yet its regulation in diabetic kidney disease (DKD) remains…”
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Effectiveness and Safety of Spironolactone in the Treatment of IgA Nephropathy: A Retrospective Self-Controlled Study
Published in Kidney & blood pressure research (2024)“…It is crucial to utilize combination therapy for immunoglobulin A nephropathy (IgAN) patients to reduce proteinuria and maintain stable kidney function. We…”
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SIRT1 attenuates renal fibrosis by repressing HIF-2α
Published in Cell death discovery (23-03-2021)“…Sirtuin 1 (SIRT1) is a nicotinamide adenine dinucleotide (NAD + )-dependent deacetylase belonging to class III histone deacetylases. Previous studies have…”
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GSK3β Mediates Renal Response to Vasopressin by Modulating Adenylate Cyclase Activity
Published in Journal of the American Society of Nephrology (01-03-2010)“…Glycogen synthase kinase 3β (GSK3β), a serine/threonine protein kinase, is a key target of drug discovery in several diseases, including diabetes and Alzheimer…”
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High glucose–induced ubiquitination of G6PD leads to the injury of podocytes
Published in The FASEB journal (01-05-2019)“…ABSTRACTOxidative stress contributes substantially to podocyte injury, which plays an important role in the development of diabetic kidney disease. The…”
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Recurrent exercise-induced acute kidney injury associated with hypouricemia: a case report and literature review
Published in BMC nephrology (21-12-2023)“…Hereditary renal hypouricemia (RHUC) is a heterogenous disorder characterized by defective uric acid (UA) reabsorption resulting in hypouricemia and increased…”
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14
The Purkinje Neuron Acts as a Central Regulator of Spatially and Functionally Distinct Cerebellar Precursors
Published in Developmental cell (11-11-2013)“…The prospective white matter (PWM) in the nascent cerebellum contains a transient germinal compartment that produces all postnatally born GABAergic inhibitory…”
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Functional iron deficiency anemia was associated with higher mortality in chronic kidney disease patients: the NHANES III follow-up study
Published in Renal failure (2023)“…Anemia, a common complication of chronic kidney disease (CKD), is associated with poor prognosis. However, it is not completely clear whether this association…”
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Plasma fibrinogen: a driver of left ventricular remodeling in patients undergoing peritoneal dialysis and its related risk factors
Published in Renal failure (2023)“…Plasma fibrinogen has been proven to be significantly associated with cardiovascular mortality in patients undergoing peritoneal dialysis (PD). The study aimed…”
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Activation of GPER1 in macrophages ameliorates UUO-induced renal fibrosis
Published in Cell death & disease (12-12-2023)“…Numerous studies have proven the critical role of macrophages in the renal fibrosis process. Notably, G Protein-coupled Estrogen Receptor 1 (GPER1), a novel…”
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Favorable outcome in PLA2R positive HBV-associated membranous nephropathy
Published in BMC nephrology (11-07-2022)“…Abstract Introduction Over half of the patients with hepatitis B virus associated membranous nephropathy (HBV-MN) were found to be phospholipase A2 receptor…”
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Prevalence of Obesity and Its Influence on Achievement of Cardiometabolic Therapeutic Goals in Chinese Type 2 Diabetes Patients: An Analysis of the Nationwide, Cross-Sectional 3B Study
Published in PloS one (04-01-2016)“…There are few data on the prevalence of obesity and its influence on achieving blood glucose, blood pressure, and blood lipid (3B) goals in Chinese type 2…”
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Prognostic values of left ventricular mass index progression in incident peritoneal dialysis patients : a prospective cohort study
Published in BMC nephrology (31-05-2022)“…Left ventricular hypertrophy (LVH) is common among patients undergoing dialysis. However, the dynamic structural changes of LV are rarely discussed. The study…”
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