Search Results - "Hany, Ahmed"
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1
Neuroprotective effect of berberine against environmental heavy metals-induced neurotoxicity and Alzheimer's-like disease in rats
Published in Food and chemical toxicology (01-01-2018)“…Heavy metals are reported as neurodegenerative disorders progenitor. They play a role in the precipitation of abnormal β-amyloid protein and…”
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2
Design, Synthesis and Cytotoxic Evaluation of Novel Chalcone Derivatives Bearing Triazolo[4,3-a]-quinoxaline Moieties as Potent Anticancer Agents with Dual EGFR Kinase and Tubulin Polymerization Inhibitory Effects
Published in Molecules (Basel, Switzerland) (01-01-2018)“…A series of hybrid of triazoloquinoxaline-chalcone derivatives - were designed, synthesized, fully characterized, and evaluated for their cytotoxic activity…”
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3
Highly Accurate Method for Boundary Value Problems with Robin Boundary Conditions
Published in Journal of nonlinear mathematical physics (01-09-2023)“…The main aim of the current paper is to construct a numerical algorithm for the numerical solutions of second-order linear and nonlinear differential equations…”
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4
Novel scaffold hopping of potent benzothiazole and isatin analogues linked to 1,2,3-triazole fragment that mimic quinazoline epidermal growth factor receptor inhibitors: Synthesis, antitumor and mechanistic analyses
Published in Bioorganic chemistry (01-10-2020)“…[Display omitted] •Introducing of 1,2,3-Triazole-based scaffold for design of EGFR inhibitors.•Anticancer screening of novel analogues against a panel of…”
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5
Assessment of Root Canal Filling Removal Effectiveness Using Micro–computed Tomography: A Systematic Review
Published in Journal of endodontics (01-04-2017)“…Abstract Introduction The removal of obturation materials from the root canal system is a primary objective in root canal retreatment procedures. This…”
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6
The Design and Development of Potent Small Molecules as Anticancer Agents Targeting EGFR TK and Tubulin Polymerization
Published in International journal of molecular sciences (30-01-2018)“…Some novel anthranilate diamides derivatives - , - and - were designed and synthesized to be evaluated for their in vitro anticancer activity. Structures of…”
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7
Microbiota-derived metabolites as drivers of gut-brain communication
Published in Gut microbes (31-12-2022)“…Alterations in the gut microbiota composition have been associated with a range of neurodevelopmental, neurodegenerative, and neuropsychiatric disorders. The…”
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8
Simultaneous sizing and energy management of multi-energy Virtual Power Plants operating in regulated energy markets
Published in International journal of electrical power & energy systems (01-10-2024)“…[Display omitted] •A VPP model, trading energy with consumers and with the grid in regulated markets, is studied.•An exhaustive search framework is proposed…”
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9
Pharmacological implications of ipriflavone against environmental metal–induced neurodegeneration and dementia in rats
Published in Environmental science and pollution research international (01-12-2021)“…Long-term exposure to environmental neurotoxic metals is implicated in the induction of dementia and cognitive decline. The present study aims to illustrate…”
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10
Development of Novel Class of Phenylpyrazolo[3,4-d]pyrimidine-Based Analogs with Potent Anticancer Activity and Multitarget Enzyme Inhibition Supported by Docking Studies
Published in International journal of molecular sciences (01-10-2023)“…Phenylpyrazolo[3,4-d]pyrimidine is considered a milestone scaffold known to possess various biological activities such as antiparasitic, antifungal,…”
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11
Root and canal anatomy of mandibular first molars using micro-computed tomography: a systematic review
Published in BMC oral health (29-05-2023)“…A thorough understanding of root and canal anatomy is crucial for successful root canal treatment outcomes. This systematic review aims to explore the…”
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12
Molecular analyses indicate profuse bacterial diversity in primary and post- treatment endodontic infections within a cohort from the United Arab Emirates-A preliminary study
Published in PloS one (15-07-2024)“…Endodontic microbiota appears to undergo evolutionary changes during disease progression from inflammation to necrosis and post-treatment. The aim of this…”
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13
Discovery of triaromatic flexible agents bearing 1,2,3-Triazole with selective and potent anti-breast cancer activity and CDK9 inhibition supported by molecular dynamics
Published in Journal of molecular structure (05-02-2022)“…•Novel chromene-based analogues linked to 1,2,3-triazole fragment were synthesized.•The target components have been screened for anticancer activity and the…”
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14
Design, Synthesis, Cytotoxic Evaluation and Molecular Docking of New Fluoroquinazolinones as Potent Anticancer Agents with Dual EGFR Kinase and Tubulin Polymerization Inhibitory Effects
Published in International journal of molecular sciences (11-06-2018)“…A series of new fluoroquinazolinone ⁻ and ⁻ derivatives was designed, prepared and screened for their in vitro cytotoxic activity against human cancer cell…”
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15
Responses of the predatory species, Coccinella undecimpunctata L. (Coleoptera: Coccinellidae), to the volatiles from its prey, Aphis craccivora Koch. and Vicia faba plant
Published in Egyptian journal of biological pest control (04-05-2021)“…Background Plants after infestation emit specific volatiles, which can influence foraging behavior of insect predators of herbivores. This work aimed to…”
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16
Synthesis, Modelling, and Anticonvulsant Studies of New Quinazolines Showing Three Highly Active Compounds with Low Toxicity and High Affinity to the GABA-A Receptor
Published in Molecules (Basel, Switzerland) (24-01-2017)“…Some novel fluorinated quinazolines ( - ) were designed and synthesized to be evaluated for their anticonvulsant activity and their neurotoxicity. Structures…”
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17
Influence of Negotiation, Glide Path, and Preflaring Procedures on Root Canal Shaping—Terminology, Basic Concepts, and a Systematic Review
Published in Journal of endodontics (01-06-2020)“…Negotiation, glide path, and preflaring are essential steps in root canal shaping procedures. This report aimed to discuss the terminology, basic concepts, and…”
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18
Design of molecular hybrids of phthalimide-triazole agents with potent selective MCF-7/HepG2 cytotoxicity: Synthesis, EGFR inhibitory effect, and metabolic stability
Published in Bioorganic chemistry (01-06-2021)“…[Display omitted] •Novel synthesis of phthalimide-triazole hybrids of EGFR inhibitors.•Click synthesis of new anticancer-based 1,2,3 triazoles.•Compound 6f…”
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19
Algorithms for Construction of Recurrence Relations for the Coefficients of the Fourier Series Expansions with Respect to Classical Discrete Orthogonal Polynomials
Published in Bulletin of the Iranian Mathematical Society (01-06-2022)“…A new formula expressing explicitly the integrals, antidifference, of discrete orthogonal polynomials { P n ( x ) : Hahn, Meixner, Kravchuk, and Charlier } of…”
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20
Novel 1,2,4‐triazole derivatives: Design, synthesis, anticancer evaluation, molecular docking, and pharmacokinetic profiling studies
Published in Archiv der Pharmazie (Weinheim) (01-12-2020)“…Three novel series of 1,2,4‐triazole derivatives were designed and synthesized as potential adenosine A2B receptor antagonists. The design of the new compounds…”
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