Search Results - "Hanusrichterová, Juliana"
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Metabolomics in Animal Models of Bronchial Asthma and Its Translational Importance for Clinics
Published in International journal of molecular sciences (29-12-2023)“…Bronchial asthma is an extremely heterogenous chronic respiratory disorder with several distinct endotypes and phenotypes. These subtypes differ not only in…”
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Effects of Green Tea Polyphenol Epigallocatechin-3-Gallate on Markers of Inflammation and Fibrosis in a Rat Model of Pulmonary Silicosis
Published in International journal of molecular sciences (17-01-2023)“…Inhalation of silica particles causes inflammatory changes leading to fibrotizing silicosis. Considering a lack of effective therapy, and a growing information…”
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Advances in the Use of N-Acetylcysteine in Chronic Respiratory Diseases
Published in Antioxidants (02-09-2023)“…N-acetylcysteine (NAC) is widely used because of its mucolytic effects, taking part in the therapeutic protocols of cystic fibrosis. NAC is also administered…”
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The Synthetic Surfactant CHF5633 Restores Lung Function and Lung Architecture in Severe Acute Respiratory Distress Syndrome in Adult Rabbits
Published in Lung (2024)“…Purpose Acute respiratory distress syndrome (ARDS) is a major cause of hypoxemic respiratory failure in adults. In ARDS extensive inflammation and leakage of…”
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Effects of early dexamethasone treatment on several markers of inflammation and fibrosis in an animal model of lung silicosis in rats – A pilot study
Published in Acta Medica Martiniana (22-12-2022)“…Lung silicosis is primarily caused by inhalation of particles of silicon oxide (silica). Despite a huge progress in understanding the interactions among the…”
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Novel pilot study on plasma metabolites and biomarkers in a rat model of silica-induced lung inflammation and fibrosis
Published in Biochimica et biophysica acta. General subjects (01-12-2024)“…Silica-induced lung damage may be associated with changes in distinct metabolites potentially serving as biomarkers. Due to the lack of metabolomic data from…”
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N -Acetylcysteine in Mechanically Ventilated Rats with Lipopolysaccharide-Induced Acute Respiratory Distress Syndrome: The Effect of Intravenous Dose on Oxidative Damage and Inflammation
Published in Biomedicines (12-12-2021)“…Treatment of acute respiratory distress syndrome (ARDS) is challenging due to its multifactorial aetiology. The benefit of antioxidant therapy was not…”
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Efficiency of exogenous surfactant combined with intravenous N-acetylcysteine in two-hit rodent model of ARDS
Published in Respiratory physiology & neurobiology (01-10-2023)“…Accumulation of reactive oxygen species during hyperoxia together with secondary bacteria-induced inflammation leads to lung damage in ventilated critically…”
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Advances in the Use of IN/I-Acetylcysteine in Chronic Respiratory Diseases
Published in Antioxidants (01-09-2023)“…N-acetylcysteine (NAC) is widely used because of its mucolytic effects, taking part in the therapeutic protocols of cystic fibrosis. NAC is also administered…”
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Factors influencing airway smooth muscle tone: a comprehensive review with a special emphasis on pulmonary surfactant
Published in American Journal of Physiology: Cell Physiology (01-09-2024)“…A thin film of pulmonary surfactant lines the surface of the airways and alveoli, where it lowers the surface tension in the peripheral lungs, preventing…”
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Sex differences in plasma metabolites in a guinea pig model of allergic asthma
Published in Physiological research (31-12-2023)“…Sex seems to be a contributing factor in the pathogenesis of bronchial asthma. This study aimed to find sex-related differences in metabolome measured by…”
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