Search Results - "Hantzopoulos, P A"

Improved Gene Expression upon Transfer of the Adenosine Deaminase Minigene outside the Transcriptional Unit of a Retroviral Vector by Hantzopoulos, Petros A., Sullenger, Bruce A., Ungers, Grace, Gilboa, Eli

“…This study describes a type of retroviral vector called double-copy (DC) vector that was designed to improve the expression of transduced genes. The unique…”
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Retroviral Gene Transfer Induced Constitutive Expression of Interleukin-2 or Interferon-γ in Irradiated Human Melanoma Cells by Gansbacher, B., Zier, K., Cronin, K., Hantzopoulos, P.A., Bouchard, B., Houghton, A., Gilboa, E., Golde, D.

“…Cytokines are important modulators of host antitumor responses. Two of these cytokines, interleukin-2 (IL-2) and interferon γ (IFN-γ), are produced after…”
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Comparison of the expression of a mutant dihydrofolate reductase under control of different internal promoters in retroviral vectors by Li, M, Hantzopoulos, P A, Banerjee, D, Zhao, S C, Schweitzer, B I, Gilboa, E, Bertino, J R

“…To determine the effect of different promoters on the expression of an altered dihydrofolate reductase (DHFR) gene conferring methotrexate (MTX) resistance in…”
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The low affinity NGF receptor, p75, can collaborate with each of the Trks to potentiate functional responses to the neurotrophins by Hantzopoulos, Petros A, Suri, Chitra, Glass, David J, Goldfarb, Mitchell P, Yancopoulos, George D

“…NGF and the other neurotrophins all bind to the low affinity NGF receptor (LNGFR). Although early studies suggested that the LNGFR was absolutely required for…”
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In vivo imaging of herpes simplex virus type 1 thymidine kinase gene expression: early kinetics of radiolabelled FIAU by Haubner, R, Avril, N, Hantzopoulos, P A, Gansbacher, B, Schwaiger, M

“…Previous studies have shown that the herpes simplex virus type 1 thymidine kinase gene (HSV1-tk), in combination with appropriate radiolabelled substrates…”
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In vivo imaging of herpes simplex virus type 1 thymidine kinase gene expression: early kinetics of radiolabelled FIAU by Haubner, Roland, Avril, Norbert, Hantzopoulos, Petros A., Gansbacher, Bernd, Schwaiger, Markus

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Reduction of breast carcinoma tumor growth and lung colonization by overexpression of the soluble urokinase-type plasminogen activator receptor (CD87) by Krüger, A, Soeltl, R, Lutz, V, Wilhelm, O G, Magdolen, V, Rojo, E E, Hantzopoulos, P A, Graeff, H, Gänsbacher, B, Schmitt, M

“…The serine protease urokinase-type plasminogen activator, uPA, when bound to its specific receptor, uPAR (CD87), plays a significant role in tumor cell…”
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Expression of the human alpha-galactosidase A in Escherichia coli K-12 by Hantzopoulos, P A, Calhoun, D H

“…We used the prokaryotic expression vector, ptrpL1, for the expression in Escherichia coli K-12 of a cDNA clone specific for the human lysosomal hydrolase,…”
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Ex vivo gene transfer of brain-derived neurotrophic factor to the intact rat forebrain: neurotrophic effects on cholinergic neurons by Martinez-Serrano, A, Hantzopoulos, P A, Björklund, A

“…Neurotrophic effects of human brain-derived neurotrophic factor (hBDNF) on forebrain cholinergic neurons were addressed after ex vivo gene transfer to the…”
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Retroviral gene transfer induced constitutive expression of interleukin- 2 or interferon-gamma in irradiated human melanoma cells by Gansbacher, B, Zier, K, Cronin, K, Hantzopoulos, PA, Bouchard, B, Houghton, A, Gilboa, E, Golde, D

“…Cytokines are important modulators of host antitumor responses. Two of these cytokines, interleukin-2 (IL-2) and interferon gamma (IFN-gamma), are produced…”
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Gene therapy--current status and outlook by Hantzopoulos, P A, Gänsbacher, B

“…None of the human gene transfer studies to date has shown definitive proof of clinical efficacy, despite more than 100 clinical protocols involving nearly 600…”
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Gentherapie – Stand und Ausblick by Hantzopoulos, P. A., Gänsbacher, B.

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