Search Results - "Hanstock, Chris"

Considerations for measuring the fractional anisotropy of metabolites with diffusion tensor spectroscopy by Ellegood, Jacob, Hanstock, Chris C., Beaulieu, Christian

“…Diffusion tensor spectroscopy of metabolites in brain is challenging because of their lower diffusivity (i.e. less signal attenuation for a given b value) and…”
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Prospective Investigation of Glutamate Levels and Percentage Gray Matter in the Medial Prefrontal Cortex in Females at Risk for Postpartum Depression by Ghuman, Arjun, McEwen, Alyssa, Tran, Kim Hoang, Mitchell, Nicholas, Hanstock, Chris, Seres, Peter, Jhangri, Gian, Burgess, Denee, Baker, Glen, Le Melledo, Jean-Michel

“…Background: The substantial female hormone fluctuations associated with pregnancy and postpartum have been linked to a greater risk of developing depressive…”
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Decreased Prefrontal Myo-Inositol in Major Depressive Disorder by Coupland, Nick J., Ogilvie, Catherine J., Hegadoren, Kathleen M., Seres, Peter, Hanstock, Chris C., Allen, Peter S.

“…Postmortem studies have shown robust prefrontal cortex glial losses and more subtle neuronal changes in major depressive disorder (MDD). Earlier proton…”
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Voxel-based morphometry reveals extra-nigral atrophy patterns associated with dopamine refractory cognitive and motor impairment in parkinsonism by Camicioli, Richard, Gee, Myrlene, Bouchard, Thomas P, Fisher, Nancy J, Hanstock, Chris C, Emery, Derek J, Martin, W.R. Wayne

“…Abstract Objectives To determine overall patterns of brain atrophy associated with memory, executive function (EF) and dopamine non-responsive motor measures…”
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Diffusion tensor spectroscopy (DTS) of human brain by Ellegood, Jacob, Hanstock, Chris C., Beaulieu, Christian

“…The diffusion tensor of N‐acetyl aspartate (NAA), creatine and phosphocreatine (tCr), and choline (Cho) was measured at 3T using a diffusion weighted STEAM…”
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Trace apparent diffusion coefficients of metabolites in human brain using diffusion weighted magnetic resonance spectroscopy by Ellegood, Jacob, Hanstock, Chris C., Beaulieu, Christian

“…The rotationally invariant trace/3 apparent diffusion coefficients (ADC) of N‐acetyl aspartate (NAA), creatine and phosphocreatine (tCr), and choline (Cho)…”
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Spectral editing of weakly coupled spins using variable flip angles in PRESS constant echo time difference spectroscopy: Application to GABA by Snyder, Jeff, Hanstock, Chris C., Wilman, Alan H.

“…A general in vivo magnetic resonance spectroscopy editing technique is presented to detect weakly coupled spin systems through subtraction, while preserving…”
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Rapid acquisition diffusion MR spectroscopy of metabolites in human brain by Hanstock, Chris, Beaulieu, Christian

“…Few studies have focused on metabolite diffusion in the human brain using 1H‐MRS due to significant technical challenges. Moreover, such studies have required…”
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Anisotropic diffusion of metabolites in peripheral nerve using diffusion weighted magnetic resonance spectroscopy at ultra-high field by Ellegood, Jacob, McKay, Ryan T., Hanstock, Chris C., Beaulieu, Christian

“…Although the diffusivity and anisotropy of water has been investigated thoroughly in ordered axonal systems (i.e., nervous tissue), there have been very few…”
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Acute dextro-amphetamine administration does not alter brain myo-inositol levels in humans and animals: MRS investigations at 3 and 18.8 T by McGrath, Brent M., McKay, Ryan, Dave, Sanjay, Seres, Peter, Weljie, Aalim M., Slupsky, Carolyn M., Hanstock, Chris C., Greenshaw, Andrew J., Silverstone, Peter H.

“…The pathophysiological underpinnings of bipolar disorder are not fully understood. However, they may be due in part to changes in the phosphatidylinositol…”
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Motor cortex and spinal degeneration in multisystem atrophy: a multimodal study by Muayqil, Taim, Chan, K Ming, Camicioli, Richard, Hanstock, Chris, Wong, John, Concha, Luis, Beaulieu, Christian, Johnston, Wendy, Stenerson, Paul, Kalra, Sanjay

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Motor cortex functional connectivity is associated with underlying neurochemistry in ALS by Dey, Avyarthana, Luk, Collin C, Ishaque, Abdullah, Ta, Daniel, Srivastava, Ojas, Krebs, Dennell, Seres, Peter, Hanstock, Chris, Beaulieu, Christian, Korngut, Lawrence, Frayne, Richard, Zinman, Lorne, Graham, Simon, Genge, Angela, Briemberg, Hannah, Kalra, Sanjay

“…ObjectiveTo identify structural and neurochemical properties that underlie functional connectivity impairments of the primary motor cortex (PMC) and how these…”
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Progressive Neurochemical Abnormalities in Cognitive and Motor Subgroups of Amyotrophic Lateral Sclerosis: A Prospective Multicenter Study by Ta, Daniel, Ishaque, Abdullah, Srivastava, Ojas, Hanstock, Chris, Seres, Peter, Eurich, Dean T., Luk, Collin, Briemberg, Hannah, Frayne, Richard, Genge, Angela L., Graham, Simon J., Korngut, Lawrence, Zinman, Lorne, Kalra, Sanjay

“…To evaluate progressive cerebral degeneration in amyotrophic lateral sclerosis (ALS) by assessing alterations in -acetylaspartate (NAA) ratios in the motor and…”
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Spectroscopic markers of neurodegeneration in the mesial prefrontal cortex predict survival in ALS by Hanstock, Chris, Sun, Kerry, Choi, Changho, Eurich, Dean, Camicioli, Richard, Johnston, Wendy, Kalra, Sanjay

“…Background and objective: N-acetylaspartate (NAA) and myo-inositol (mIns) are spectroscopic markers of neuronal integrity and astrogliosis, respectively. We…”
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3-T Proton MRS Investigation of Glutamate and Glutamine in Adolescents at High Genetic Risk for Schizophrenia by Tibbo, Philip, Hanstock, Chris, Valiakalayil, Agitha, Allen, Peter

“…OBJECTIVE: Glutamate and glutamine were examined in vivo in nonpsychotic adolescents at high genetic risk for schizophrenia by using 3-T proton magnetic…”
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Ventricular dilatation and brain atrophy in patients with Parkinson's disease with incipient dementia by Camicioli, Richard, Sabino, Jennifer, Gee, Myrlene, Bouchard, Thomas, Fisher, Nancy, Hanstock, Chris, Emery, Derek, Martin, W.R. Wayne

“…Age‐related ventricular enlargement is accelerated in Alzheimer's disease, but its relationship to cognitive decline in Parkinson's disease is less clear, even…”
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Combined structural and neurochemical evaluation of the corticospinal tract in amyotrophic lateral sclerosis by Pyra, Timothy, Hui, Benjamin, Hanstock, Chris, Concha, Luis, Wong, John C.T., Beaulieu, Christian, Johnston, Wendy, Kalra, Sanjay

“…Our objective was to characterize the structural and metabolic changes of the corticospinal tract (CST) in ALS patients using combined diffusion tensor imaging…”
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Cerebral degeneration in amyotrophic lateral sclerosis: A prospective multicenter magnetic resonance spectroscopy study by Srivastava, Ojas, Hanstock, Chris, Chenji, Sneha, Mah, Dennell, Eurich, Dean, Ta, Daniel, Seres, Peter, Luk, Collin, Zinman, Lorne, Abrahao, Agessandro, Graham, Simon J, Genge, Angela, Korngut, Lawrence, Frayne, Richard, Kalra, Sanjay

“…We investigated cerebral degeneration and neurochemistry in patients with amyotrophic lateral sclerosis (ALS) using magnetic resonance spectroscopy (MRS). We…”
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Proton Magnetic Resonance Spectroscopy Measurement of Brain Glutamate Levels in Premenstrual Dysphoric Disorder by Batra, Neha Arun, Seres-Mailo, Janette, Hanstock, Chris, Seres, Peter, Khudabux, Janisse, Bellavance, François, Baker, Glen, Allen, Peter, Tibbo, Philip, Hui, Eric, Le Melledo, Jean-Michel

“…Background Women who suffer from premenstrual dysphoric disorder (PMDD) classically display depressive and anxiety symptoms in the premenstrum. Preclinical and…”
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Investigation of 3T 1H-MRS and psychotic symptoms in unmedicated first episode psychosis by Tibbo, Philip, Bernier, Denise, Seres, Peter, Hanstock, Chris, Nguyen-Burns, Amy, Purdon, Scot

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