Search Results - "Hansson, J."

KIT, NRAS and BRAF mutations in sinonasal mucosal melanoma: a study of 56 cases by Zebary, A, Jangard, M, Omholt, K, Ragnarsson-Olding, B, Hansson, J

“…Background: Mucosal melanomas in the head and neck region are most frequently located in the nasal cavity and paranasal sinuses. Sinonasal mucosal melanoma…”
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Randomized clinical trial of antibiotic therapy versus appendicectomy as primary treatment of acute appendicitis in unselected patients by Hansson, J., Körner, U., Khorram-Manesh, A., Solberg, A., Lundholm, K.

“…Background: A trial in selected men suggested that antibiotic therapy could be an alternative to appendicectomy in appendicitis. This study aimed to evaluate…”
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Vismodegib in patients with advanced basal cell carcinoma: Primary analysis of STEVIE, an international, open-label trial by Basset-Séguin, N., Hauschild, A., Kunstfeld, R., Grob, J., Dréno, B., Mortier, L., Ascierto, P.A., Licitra, L., Dutriaux, C., Thomas, L., Meyer, N., Guillot, B., Dummer, R., Arenberger, P., Fife, K., Raimundo, A., Dika, E., Dimier, N., Fittipaldo, A., Xynos, I., Hansson, J.

“…The SafeTy Events in VIsmodEgib study (STEVIE, ClinicalTrials.gov, NCT01367665), assessed safety and efficacy of vismodegib—a first-in-class Hedgehog pathway…”
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Dabrafenib plus trametinib versus dabrafenib monotherapy in patients with metastatic BRAF V600E/K-mutant melanoma: long-term survival and safety analysis of a phase 3 study by Long, G.V., Flaherty, K.T., Stroyakovskiy, D., Gogas, H., Levchenko, E., de Braud, F., Larkin, J., Garbe, C., Jouary, T., Hauschild, A., Chiarion-Sileni, V., Lebbe, C., Mandalà, M., Millward, M., Arance, A., Bondarenko, I., Haanen, J.B.A.G., Hansson, J., Utikal, J., Ferraresi, V., Mohr, P., Probachai, V., Schadendorf, D., Nathan, P., Robert, C., Ribas, A., Davies, M.A., Lane, S.R., Legos, J.J., Mookerjee, B., Grob, J.-J.

“…Previous analysis of COMBI-d (NCT01584648) demonstrated improved progression-free survival (PFS) and overall survival (OS) with combination dabrafenib and…”
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A hypothesis regarding how sleep can calibrate neuronal excitability in the central nervous system and thereby offer stability, sensitivity and the best possible cognitive function by Hansson, J.H. Sture

“…The function of sleep in mammal and other vertebrates is one of the great mysteries of biology. Many hypotheses have been proposed, but few of these have made…”
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Cell-permeable succinate prodrugs bypass mitochondrial complex I deficiency by Ehinger, Johannes K., Piel, Sarah, Ford, Rhonan, Karlsson, Michael, Sjövall, Fredrik, Frostner, Eleonor Åsander, Morota, Saori, Taylor, Robert W., Turnbull, Doug M., Cornell, Clive, Moss, Steven J., Metzsch, Carsten, Hansson, Magnus J., Fliri, Hans, Elmér, Eskil

“…Mitochondrial complex I (CI) deficiency is the most prevalent defect in the respiratory chain in paediatric mitochondrial disease. This heterogeneous group of…”
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Lethal aplastic anemia caused by dual immune checkpoint blockade in metastatic melanoma by Helgadottir, H., Kis, L., Ljungman, P., Larkin, J., Kefford, R., Ascierto, P.A., Hansson, J., Masucci, G.

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Radiographers’ perspectives’ on Visual Grading Analysis as a scientific method to evaluate image quality by Precht, H., Hansson, J., Outzen, C., Hogg, P., Tingberg, A.

“…Radiographers routinely undertake many initiatives to balance image quality with radiation dose (optimisation). For optimisation studies to be successful image…”
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Microchannel acoustophoresis does not impact survival or function of microglia, leukocytes or tumor cells by Burguillos, Miguel A, Magnusson, Cecilia, Nordin, Maria, Lenshof, Andreas, Augustsson, Per, Hansson, Magnus J, Elmér, Eskil, Lilja, Hans, Brundin, Patrik, Laurell, Thomas, Deierborg, Tomas

“…The use of acoustic forces to manipulate particles or cells at the microfluidic scale (i.e. acoustophoresis), enables non-contact, label-free separation based…”
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α1-Microglobulin (A1M) Protects Human Proximal Tubule Epithelial Cells from Heme-Induced Damage In Vitro by Kristiansson, Amanda, Davidsson, Sara, Johansson, Maria E., Piel, Sarah, Elmér, Eskil, Hansson, Magnus J., Åkerström, Bo, Gram, Magnus

“…Oxidative stress is associated with many renal disorders, both acute and chronic, and has also been described to contribute to the disease progression…”
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Mitochondrial dysfunction in blood cells from amyotrophic lateral sclerosis patients by Ehinger, Johannes K., Morota, Saori, Hansson, Magnus J., Paul, Gesine, Elmér, Eskil

“…Mitochondrial dysfunction is implicated in amyotrophic lateral sclerosis, where the progressive degeneration of motor neurons results in muscle atrophy,…”
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Quantitative analysis of redox proteome reveals oxidation-sensitive protein thiols acting in fundamental processes of developmental hematopoiesis by Pimkova, K., Jassinskaja, M., Munita, R., Ciesla, M., Guzzi, N., Cao Thi Ngoc, P., Vajrychova, M., Johansson, E., Bellodi, C., Hansson, J.

“…Fetal and adult hematopoietic stem and progenitor cells (HSPCs) are characterized by distinct redox homeostasis that may influence their differential cellular…”
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Cell-permeable succinate prodrugs rescue mitochondrial respiration in cellular models of acute acetaminophen overdose by Piel, Sarah, Chamkha, Imen, Dehlin, Adam Kozak, Ehinger, Johannes K, Sjövall, Fredrik, Elmér, Eskil, Hansson, Magnus J

“…Acetaminophen is one of the most common over-the-counter pain medications used worldwide and is considered safe at therapeutic dose. However, intentional and…”
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Long-Term Results Following Antibiotic Treatment of Acute Appendicitis in Adults by Lundholm, K., Hansson-Assarsson, J., Engström, C., Iresjö, B.-M.

“…Background Antibiotic treatment of acute appendicitis has gained interest and inquiries. Reports have demonstrated both safety and high resolution of symptoms…”
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Cell-Permeable Succinate Rescues Mitochondrial Respiration in Cellular Models of Statin Toxicity by Avram, Vlad F, Chamkha, Imen, Åsander-Frostner, Eleonor, Ehinger, Johannes K, Timar, Romulus Z, Hansson, Magnus J, Muntean, Danina M, Elmér, Eskil

“…Statins are the cornerstone of lipid-lowering therapy. Although generally well tolerated, statin-associated muscle symptoms (SAMS) represent the main reason…”
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Succinate prodrugs in combination with atropine and pralidoxime protect cerebral mitochondrial function in a rodent model of acute organophosphate poisoning by Piel, Sarah, Janowska, Joanna I., Ward, J. Laurenson, McManus, Meagan J., Jose, Joshua S., Starr, Jonathan, Sheldon, Malkah, Clayman, Carly L., Elmér, Eskil, Hansson, Magnus J., Jang, David H., Karlsson, Michael, Ehinger, Johannes K., Kilbaugh, Todd J.

“…Pesticides account for hundreds of millions of cases of acute poisoning worldwide each year, with organophosphates (OPs) being responsible for the majority of…”
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Stage-specific survival and recurrence in patients with cutaneous malignant melanoma in Europe - a systematic review of the literature by Svedman, Fernanda Costa, Pillas, Demetris, Taylor, Aliki, Kaur, Moninder, Linder, Ragnar, Hansson, Johan

“…Given the increasing incidence in cutaneous malignant melanoma (CMM) and the recent changes in the treatment landscape, it is important to understand…”
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Targeting CDK2 overcomes melanoma resistance against BRAF and Hsp90 inhibitors by Azimi, Alireza, Caramuta, Stefano, Seashore‐Ludlow, Brinton, Boström, Johan, Robinson, Jonathan L, Edfors, Fredrik, Tuominen, Rainer, Kemper, Kristel, Krijgsman, Oscar, Peeper, Daniel S, Nielsen, Jens, Hansson, Johan, Egyhazi Brage, Suzanne, Altun, Mikael, Uhlen, Mathias, Maddalo, Gianluca

“…Novel therapies are undergoing clinical trials, for example, the Hsp90 inhibitor, XL888, in combination with BRAF inhibitors for the treatment of…”
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Exploring the potential of a multi-level approach to improve capability for continuous organizational improvement and learning in a Swedish healthcare region by Nyström, M E, Höög, E, Garvare, R, Andersson Bäck, M, Terris, D D, Hansson, J

“…Eldercare and care of people with functional impairments is organized by the municipalities in Sweden. Improving care in these areas is complex, with multiple…”
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Genes involved in DNA replication, chromatin remodeling and cell cycle as potential biomarkers for therapy outcome to immune therapy in patients with metastatic cutaneous malignant melanoma by Svedman, F Costa, Das, I., Tuominen, R., Ramqvist, E.D., Hansson, J., Höiom, V., Brage, S Egyhazi

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