Search Results - "Hanson, I"

Multivesicular Body Morphogenesis by Hanson, Phyllis I, Cashikar, Anil

“…Multivesicular bodies (MVBs) are unique organelles in the endocytic pathway that contain vesicles in their lumen. Sorting and incorporation of material into…”
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STAT1 Gain of Function, Type 1 Diabetes, and Reversal with JAK Inhibition by Chaimowitz, Natalia S, Ebenezer, Sophia J, Hanson, I. Celine, Anderson, Mark, Forbes, Lisa R

“…This letter describes the case of an adolescent boy with heterozygous STAT1 gain-of-function syndrome and type 1 diabetes. Diabetes and other features of the…”
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Triggered recruitment of ESCRT machinery promotes endolysosomal repair by Skowyra, Michael L, Schlesinger, Paul H, Naismith, Teresa V, Hanson, Phyllis I

“…Endolysosomes can be damaged by diverse materials. Terminally damaged compartments are degraded by lysophagy, but pathways that repair salvageable organelles…”
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Membrane budding and scission by the ESCRT machinery: it's all in the neck by Hurley, James H, Hanson, Phyllis I

“…Key Points Endosomal sorting complexes required for transport (ESCRTs) are required for the lysosomal degradation of plasma membrane proteins, budding of most…”
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Working on the boundaries—How do science use and interpret the nature-based solution concept? by Hanson, Helena I., Wickenberg, Björn, Alkan Olsson, Johanna

“…•The NBS concept is mainly used within the urban European context.•The environmental research fields dominate use and interpretation.•The uptake is linked to…”
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Vaccine-Acquired Rotavirus in Infants with Severe Combined Immunodeficiency by Patel, Niraj C, Hertel, Paula M, Estes, Mary K, de la Morena, Maite, Petru, Ann M, Noroski, Lenora M, Revell, Paula A, Hanson, I. Celine, Paul, Mary E, Rosenblatt, Howard M, Abramson, Stuart L

“…The rotavirus vaccine is being widely implemented and must be given early in life to minimize the risk of intussusception. In this report, rotaviral infection…”
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Structure and membrane remodeling activity of ESCRT-III helical polymers by McCullough, John, Clippinger, Amy K., Talledge, Nathaniel, Skowyra, Michael L., Saunders, Marissa G., Naismith, Teresa V., Colf, Leremy A., Afonine, Pavel, Arthur, Christopher, Sundquist, Wesley I., Hanson, Phyllis I., Frost, Adam

“…The endosomal sorting complexes required for transport (ESCRT) proteins mediate fundamental membrane remodeling events that require stabilizing negative…”
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A cell-based assay for CD63-containing extracellular vesicles by Cashikar, Anil G, Hanson, Phyllis I

“…Extracellular vesicles (EVs) are thought to be important in cell-cell communication and have elicited extraordinary interest as potential biomarkers of…”
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Effects of Inhibiting VPS4 Support a General Role for ESCRTs in Extracellular Vesicle Biogenesis by Jackson, Charles E., Scruggs, Benjamin S., Schaffer, Jean E., Hanson, Phyllis I.

“…Extracellular vesicles (EVs) are proposed to play important roles in intercellular communication. Two classes of EVs can be distinguished based on their…”
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X-linked lymphoproliferative disease due to SAP/SH2D1A deficiency: a multicenter study on the manifestations, management and outcome of the disease by Booth, Claire, Gilmour, Kimberly C., Veys, Paul, Gennery, Andrew R., Slatter, Mary A., Chapel, Helen, Heath, Paul T., Steward, Colin G., Smith, Owen, O'Meara, Anna, Kerrigan, Hilary, Mahlaoui, Nizar, Cavazzana-Calvo, Marina, Fischer, Alain, Moshous, Despina, Blanche, Stephane, Pachlopnik Schmid, Jana, Latour, Sylvain, de Saint-Basile, Genevieve, Albert, Michael, Notheis, Gundula, Rieber, Nikolaus, Strahm, Brigitte, Ritterbusch, Henrike, Lankester, Arjan, Hartwig, Nico G., Meyts, Isabelle, Plebani, Alessandro, Soresina, Annarosa, Finocchi, Andrea, Pignata, Claudio, Cirillo, Emilia, Bonanomi, Sonia, Peters, Christina, Kalwak, Krzysztof, Pasic, Srdjan, Sedlacek, Petr, Jazbec, Janez, Kanegane, Hirokazu, Nichols, Kim E., Hanson, I. Celine, Kapoor, Neena, Haddad, Elie, Cowan, Morton, Choo, Sharon, Smart, Joanne, Arkwright, Peter D., Gaspar, Hubert B.

“…X-linked lymphoproliferative disease (XLP1) is a rare immunodeficiency characterized by severe immune dysregulation and caused by mutations in the SH2D1A/SAP…”
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Plasma membrane deformation by circular arrays of ESCRT-III protein filaments by Hanson, Phyllis I, Roth, Robyn, Lin, Yuan, Heuser, John E

“…Endosomal sorting complex required for transport III (ESCRT-III) proteins function in multivesicular body biogenesis and viral budding. They are recruited from…”
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Lentiviral hematopoietic stem cell gene therapy for X-linked severe combined immunodeficiency by De Ravin, Suk See, Wu, Xiaolin, Moir, Susan, Anaya-O'Brien, Sandra, Kwatemaa, Nana, Littel, Patricia, Theobald, Narda, Choi, Uimook, Su, Ling, Marquesen, Martha, Hilligoss, Dianne, Lee, Janet, Buckner, Clarissa M, Zarember, Kol A, O'Connor, Geraldine, McVicar, Daniel, Kuhns, Douglas, Throm, Robert E, Zhou, Sheng, Notarangelo, Luigi D, Hanson, I Celine, Cowan, Mort J, Kang, Elizabeth, Hadigan, Coleen, Meagher, Michael, Gray, John T, Sorrentino, Brian P, Malech, Harry L, Kardava, Lela

“…X-linked severe combined immunodeficiency (SCID-X1) is a profound deficiency of T, B, and natural killer (NK) cell immunity caused by mutations inIL2RGencoding…”
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Combination Antiretroviral Strategies for the Treatment of Pregnant HIV-1-Infected Women and Prevention of Perinatal HIV-1 Transmission by Cooper, Ellen R, Charurat, Manhattan, Mofenson, Lynne, Hanson, Celine I, Pitt, Jane, Diaz, Clemente, Hayani, Karen, Handelsman, Edward, Smeriglio, Vincent, Hoff, Rodney, Blattner, William

“…CONTEXT:The Women and Infants Transmission Study is a prospective natural history study that has been enrolling HIV-1-infected pregnant women and their infants…”
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Adoptive immunotherapy for primary immunodeficiency disorders with virus-specific T lymphocytes by Naik, Swati, MD, Nicholas, Sarah K., MD, Martinez, Caridad A., MD, Leen, Ann M., PhD, Hanley, Patrick J., PhD, Gottschalk, Steven M., MD, Rooney, Cliona M., PhD, Hanson, I. Celine, MD, PhD, Krance, Robert A., MD, Shpall, Elizabeth J., MD, Cruz, Conrad R., MD, PhD, Amrolia, Persis, MD, Lucchini, Giovanna, MD, Bunin, Nancy, MD, Heimall, Jennifer, MD, Klein, Orly R., MD, Gennery, Andrew R., MD, Slatter, Mary A., MD, Vickers, Mark A., MD, Orange, Jordan S., MD, PhD, Heslop, Helen E., MD, PhD, Bollard, Catherine M., MD, Keller, Michael D., MD

“…Background Viral infections are a leading fatal complication for patients with primary immunodeficiencies (PIDs) who require hematopoietic stem cell…”
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Mycobacterium tuberculosis Type VII Secretion System Effectors Differentially Impact the ESCRT Endomembrane Damage Response by Mittal, Ekansh, Skowyra, Michael L, Uwase, Grace, Tinaztepe, Emir, Mehra, Alka, Köster, Stefan, Hanson, Phyllis I, Philips, Jennifer A

“…Intracellular pathogens have varied strategies to breach the endolysosomal barrier so that they can deliver effectors to the host cytosol, access nutrients,…”
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Agricultural Land Use Determines the Trait Composition of Ground Beetle Communities by Hanson, Helena I, Palmu, Erkki, Birkhofer, Klaus, Smith, Henrik G, Hedlund, Katarina

“…In order to improve biological control of agricultural pests, it is fundamental to understand which factors influence the composition of natural enemies in…”
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Redefining the Breast Cancer Exosome Proteome by Tandem Mass Tag Quantitative Proteomics and Multivariate Cluster Analysis by Clark, David J, Fondrie, William E, Liao, Zhongping, Hanson, Phyllis I, Fulton, Amy, Mao, Li, Yang, Austin J

“…Exosomes are microvesicles of endocytic origin constitutively released by multiple cell types into the extracellular environment. With evidence that exosomes…”
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Somatic reversion in dedicator of cytokinesis 8 immunodeficiency modulates disease phenotype by Jing, Huie, PhD, Zhang, Qian, MD, Zhang, Yu, PhD, Hill, Brenna J., PhD, Dove, Christopher G., BS, Gelfand, Erwin W., MD, Atkinson, T. Prescott, MD, PhD, Uzel, Gulbu, MD, Matthews, Helen F., RN, Mustillo, Peter J., MD, Lewis, David B., MD, Kavadas, Fotini D., MD, Hanson, I. Celine, MD, Kumar, Ashish R., MD, PhD, Geha, Raif S., MD, Douek, Daniel C., MD, PhD, Holland, Steven M., MD, Freeman, Alexandra F., MD, Su, Helen C., MD, PhD

“…Background Autosomal recessive loss-of-function mutations in dedicator of cytokinesis 8 (DOCK8) cause a combined immunodeficiency characterized by atopy,…”
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Integration of the ecosystem services concept in planning documents from six municipalities in southwestern Sweden by Nordin, Amanda C., Hanson, Helena I., Olsson, Johanna Alkan

“…The ecosystem services (ES) concept refers to benefits that humanity receives from nature. Investigating how this concept has been embraced within urban…”
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AAA+ proteins: have engine, will work by Hanson, Phyllis I, Whiteheart, Sidney W

“…The AAA+ (ATPases associated with various cellular activities) family is a large and functionally diverse group of enzymes that are able to induce…”
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