Search Results - "Hanson, Dennis A"

Sp1 Family of Transcription Factors Regulates the Human α2 (XI) Collagen Gene (COL11A2) in Saos‐2 Osteoblastic Cells by Goto, Tomohiro, Matsui, Yoshito, Fernandes, Russell J, Hanson, Dennis A, Kubo, Takahiro, Yukata, Kiminori, Michigami, Toshimi, Komori, Toshihisa, Fujita, Takashi, Yang, Liu, Eyre, David R, Yasui, Natsuo

“…Genes encoding type XI collagen, normally associated with chondrogenesis, are also expressed by osteoblasts. By studying Saos‐2 cells, we showed that the…”
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Granulysin-Induced Apoptosis. I. Involvement of at Least Two Distinct Pathways by Gamen, Susana, Hanson, Dennis A, Kaspar, Allan, Naval, Javier, Krensky, Alan M, Anel, Alberto

“…Granulysin is a newly described cytolytic molecule released by CTL and NK cells via granule-mediated exocytosis. It shares homology with saposin-like proteins,…”
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Biosynthesis of granulysin, a novel cytolytic molecule by Hanson, Dennis A, Kaspar, Allan A, Poulain, Francis R, Krensky, Alan M

“…Granulysin is a newly described lytic molecule expressed by CTL and NK cells. Three mRNA (519, 520, and 522) and two protein products of 15 and 9 kDa are…”
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Regulation of ionomycin-mediated granule release from rat basophil leukemia cells by Hanson, Dennis A, Ziegler, Steven F

“…Cross-linking the high affinity IgE receptor on the rat basophil leukemia clone 2H3 (RBL-2H3) cell line, an vitro model for mast cell signaling, results in…”
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Fusion of green fluorescent protein to the C-terminus of granulysin alters its intracellular localization in comparison to the native molecule by Hanson, Dennis A, Ziegler, Steven F

“…The engineering of green fluorescent protein (GFP) fusion constructs in order to visibly tag a protein of interest has become a commonly used cell biology…”
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An Antimicrobial Activity of Cytolytic T Cells Mediated by Granulysin by Stenger, Steffen, Hanson, Dennis A., Teitelbaum, Rachel, Dewan, Puneet, Niazi, Kayvan R., Froelich, Christopher J., Ganz, Tomas, Thoma-Uszynski, Sybille, Melián, Agustín, Bogdan, Christian, Porcelli, Steven A., Bloom, Barry R., Krensky, Alan M., Modlin, Robert L.

“…Cytolytic T lymphocytes (CTLs) kill intracellular pathogens by a granule-dependent mechanism. Granulysin, a protein found in granules of CTLs, reduced the…”
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Granulysin, a T Cell Product, Kills Bacteria by Altering Membrane Permeability by Ernst, William A, Thoma-Uszynski, Sybille, Teitelbaum, Rachel, Ko, Christine, Hanson, Dennis A, Clayberger, Carol, Krensky, Alan M, Leippe, Matthias, Bloom, Barry R, Ganz, Tomas, Modlin, Robert L

“…Granulysin, a protein located in the acidic granules of human NK cells and cytotoxic T cells, has antimicrobial activity against a broad spectrum of microbial…”
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Molecular Site Specificity of Pyridinoline and Pyrrole Cross-links in Type I Collagen of Human Bone by Hanson, D A, Eyre, D R

“…Compared with soft tissue collagens, bone type I collagen displays a distinctive pattern of covalent cross-linking, with evidence of preferred sites of…”
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A Distinct Pathway of Cell-Mediated Apoptosis Initiated by Granulysin by Kaspar, Allan A, Okada, Satoshi, Kumar, Jayant, Poulain, Francis R, Drouvalakis, Katerina A, Kelekar, Ameeta, Hanson, Dennis A, Kluck, Ruth M, Hitoshi, Yasumichi, Johnson, Daniel E, Froelich, Christopher J, Thompson, Craig B, Newmeyer, Donald D, Anel, Alberto, Clayberger, Carol, Krensky, Alan M

“…Granulysin is an antimicrobial and tumoricidal molecule expressed in granules of CTL and NK cells. In this study, we show that granulysin damages cell…”
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A specific immunoassay for monitoring human bone resorption: Quantitation of type I collagen cross‐linked N‐telopeptides in urine by Hanson, Dennis A., Weis, Mary Ann E., Bollen, Anne‐Marie, Maslan, Shoshana L., Singer, Frederick R., Eyre, David R.

“…Peptides of low molecular weight that contain pyridinoline cross‐links were isolated from adolescent human urine. A fraction was selected that was enriched in…”
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Self-recognition of CD1 by gamma/delta T cells: implications for innate immunity by Spada, F M, Grant, E P, Peters, P J, Sugita, M, Melián, A, Leslie, D S, Lee, H K, van Donselaar, E, Hanson, D A, Krensky, A M, Majdic, O, Porcelli, S A, Morita, C T, Brenner, M B

“…The specificity of immunoglobulins and alpha/beta T cell receptors (TCRs) provides a framework for the molecular basis of antigen recognition. Yet, evolution…”
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Processing, subcellular localization, and function of 519 (granulysin), a human late T cell activation molecule with homology to small, lytic, granule proteins by Pena, SV, Hanson, DA, Carr, BA, Goralski, TJ, Krensky, AM

“…CTL and NK cells share a common cytolytic mechanism that involves regulated exocytosis of lytic molecules stored within cytoplasmic granules. Here we describe…”
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Sp1 family of transcription factors regulates the human alpha2 (XI) collagen gene (COL11A2) in Saos-2 osteoblastic cells by Goto, Tomohiro, Matsui, Yoshito, Fernandes, Russell J, Hanson, Dennis A, Kubo, Takahiro, Yukata, Kiminori, Michigami, Toshimi, Komori, Toshihisa, Fujita, Takashi, Yang, Liu, Eyre, David R, Yasui, Natsuo

“…Genes encoding type XI collagen, normally associated with chondrogenesis, are also expressed by osteoblasts. By studying Saos-2 cells, we showed that the…”
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The Sp1 Family of Transcription Factors Regulates the Human Alpha 2 (XI) Collagen Gene ( COL11A2 ) in Saos-2 Osteoblastic Cells by Goto, Tomohiro, Matsui, Yoshito, Fernandes, Russell J., Hanson, Dennis A., Kubo, Takahiro, Yukata, Kiminori, Michigami, Toshimi, Komori, Toshihisa, Fujita, Takashi, Yang, Liu, Eyre, David R., Yasui, Natsuo

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Granulysin-Induced Lysis of Membranes Depends on pH and the Net Charge of Phospholipids by Kaspar, Allan, Hanson, Dennis A, Krensky, Alan M, Hawgood, Samuel, Poulain, Francis R

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Self-Recognition of Cd1 by γ/δ T Cells by Spada, Franca M., Grant, Ethan P., Peters, Peter J., Sugita, Masahiko, Melián, Augustín, Leslie, David S., Lee, Hoi K., van Donselaar, Elly, Hanson, Dennis A., Krensky, Alan M., Majdic, Otto, Porcelli, Steven A., Morita, Craig T., Brenner, Michael B.

“…The specificity of immunoglobulins and α/β T cell receptors (TCRs) provides a framework for the molecular basis of antigen recognition. Yet, evolution has…”
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Double Inversion Recovery Magnetic Resonance Imaging in Identifying Focal Cortical Dysplasia by Wong-Kisiel, Lily C., MD, Britton, Jeffrey W., MD, Witte, Robert J., MD, Kelly-Williams, Kristen M., MD, Kotsenas, Amy L., MD, Krecke, Karl N., MD, Watson, Robert E., MD, PhD, Patton, Alice, MD, Hanson, Dennis P., MA, BS, Mandrekar, Jay, PhD

“…Abstract Background Focal cortical dysplasia is commonly recognized in pediatric epilepsy surgery. Despite characteristic radiographic features, focal cortical…”
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