Search Results - "Hanson, C A"
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CSF3R T618I is a highly prevalent and specific mutation in chronic neutrophilic leukemia
Published in Leukemia (01-09-2013)“…Truncation mutations of the receptor cytoplasmic domain for colony-stimulating factor 3 (CSF3R) are frequently seen in severe congenital neutropenia, whereas…”
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CALR and ASXL1 mutations-based molecular prognostication in primary myelofibrosis: an international study of 570 patients
Published in Leukemia (01-07-2014)“…Current prognostication in primary myelofibrosis (PMF) is based on the dynamic international prognostic scoring system (DIPSS)-plus, which employs clinical and…”
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Prevalence and clinicopathologic correlates of JAK2 exon 12 mutations in JAK2V617F-negative polycythemia vera
Published in Leukemia (01-09-2007)“…After accounting for misdiagnosis and treatment effect, allele-specific (AS)-PCR detects the JAK2V617F mutation in >95% of polycythemia vera (PV) patients…”
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Type 1 vs type 2 calreticulin mutations in primary myelofibrosis: differences in phenotype and prognostic impact
Published in Leukemia (01-07-2014)Get full text
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The number of prognostically detrimental mutations and prognosis in primary myelofibrosis: an international study of 797 patients
Published in Leukemia (01-09-2014)“…We recently defined a high-molecular risk category (HMR) in primary myelofibrosis (PMF), based on the presence of at least one of the five ‘prognostically…”
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TET2 mutations and their clinical correlates in polycythemia vera, essential thrombocythemia and myelofibrosis
Published in Leukemia (01-05-2009)“…High-throughput DNA sequence analysis was used to screen for TET2 mutations in bone marrow-derived DNA from 239 patients with BCR-ABL -negative…”
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Low JAK2V617F allele burden in primary myelofibrosis, compared to either a higher allele burden or unmutated status, is associated with inferior overall and leukemia-free survival
Published in Leukemia (01-04-2008)“…The clinical relevance of JAK2 V617F allele burden in primary myelofibrosis (PMF) has not been previously studied. Bone marrow-derived DNA from 199 patients…”
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Risk factors for arterial versus venous thrombosis in polycythemia vera: a single center experience in 587 patients
Published in Blood cancer journal (New York) (27-12-2017)“…In a recent International Working Group on Myeloproliferative Neoplasms Research and Treatment (IWG-MRT) study, prior arterial events and hypertension were…”
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Detection of mutant TET2 in myeloid malignancies other than myeloproliferative neoplasms: CMML, MDS, MDS/MPN and AML
Published in Leukemia (01-07-2009)Get full text
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10
SF3B1 mutations in primary myelofibrosis: clinical, histopathology and genetic correlates among 155 patients
Published in Leukemia (01-05-2012)Get full text
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Prognostic significance of ASXL1 mutation types and allele burden in myelofibrosis
Published in Leukemia (01-03-2018)Get full text
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Calreticulin mutations and long-term survival in essential thrombocythemia
Published in Leukemia (01-12-2014)“…The impact of calreticulin ( CALR ) mutations on long-term survival in essential thrombocythemia (ET) was examined in 299 patients whose diagnosis predated…”
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Mechanical and Microstructural Behavior of Tempered CPM® 3V High-Density Sintered Tool Steel
Published in Crystals (Basel) (01-11-2022)“…The tempering response of CPM® 3V tool steel was investigated via a hardening and tempering heat treatment, tensile testing, fractography, and microstructural…”
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Differential prognostic effect of IDH1 versus IDH2 mutations in myelodysplastic syndromes: a Mayo Clinic Study of 277 patients
Published in Leukemia (01-01-2012)“…Unlike the case with acute myeloid leukemia, there is limited information on the prognostic impact of isocitrate dehydrogenase ( IDH ) mutations in…”
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Prognostic interaction between ASXL1 and TET2 mutations in chronic myelomonocytic leukemia
Published in Blood cancer journal (New York) (01-01-2016)“…Mutations involving epigenetic regulators ( TET2 ~60% and ASXL1 ~40%) and splicing components ( SRSF2 ~50%) are frequent in chronic myelomonocytic leukemia…”
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Monosomal karyotype in myelodysplastic syndromes, with or without monosomy 7 or 5, is prognostically worse than an otherwise complex karyotype
Published in Leukemia (01-02-2011)“…Monosomal karyotype (MK) refers to the presence of two or more distinct autosomal monosomies or a single monosomy associated with a structural abnormality. In…”
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IPSS-independent prognostic value of plasma CXCL10, IL-7 and IL-6 levels in myelodysplastic syndromes
Published in Leukemia (01-04-2012)“…Recent studies suggest a powerful prognostic value for plasma cytokine levels in primary myelofibrosis (interleukin (IL)-2R, IL-8, IL-12, IL-15 and C–X–C motif…”
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Long-term follow-up of FIP1L1-PDGFRA-mutated patients with eosinophilia: survival and clinical outcome
Published in Leukemia (01-11-2012)Get full text
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WHO-defined ‘myelodysplastic syndrome with isolated del(5q)’ in 88 consecutive patients: survival data, leukemic transformation rates and prevalence of JAK2, MPL and IDH mutations
Published in Leukemia (01-07-2010)“…The 2008 World Health Organization (WHO) criteria were used to identify 88 consecutive Mayo Clinic patients with ‘myelodysplastic syndrome with isolated…”
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