Search Results - "Hanson, Anne"

Tau-targeting antisense oligonucleotide MAPTRx in mild Alzheimer’s disease: a phase 1b, randomized, placebo-controlled trial by Mummery, Catherine J., Börjesson-Hanson, Anne, Blackburn, Daniel J., Vijverberg, Everard G. B., De Deyn, Peter Paul, Ducharme, Simon, Jonsson, Michael, Schneider, Anja, Rinne, Juha O., Ludolph, Albert C., Bodenschatz, Ralf, Kordasiewicz, Holly, Swayze, Eric E., Fitzsimmons, Bethany, Mignon, Laurence, Moore, Katrina M., Yun, Chris, Baumann, Tiffany, Li, Dan, Norris, Daniel A., Crean, Rebecca, Graham, Danielle L., Huang, Ellen, Ratti, Elena, Bennett, C. Frank, Junge, Candice, Lane, Roger M.

“…Tau plays a key role in Alzheimer’s disease (AD) pathophysiology, and accumulating evidence suggests that lowering tau may reduce this pathology. We sought to…”
Get full text

Decreasing prevalence of dementia in 85-year olds examined 22 years apart: the influence of education and stroke by Skoog, Ingmar, Börjesson-Hanson, Anne, Kern, Silke, Johansson, Lena, Falk, Hanna, Sigström, Robert, Östling, Svante

“…Individuals aged 80 years and older constitute the fastest growing segment of the population worldwide, leading to an expected increase in dementia cases…”
Get full text

Prevalence of preclinical Alzheimer disease: Comparison of current classification systems by Kern, Silke, Zetterberg, Henrik, Kern, Jürgen, Zettergren, Anna, Waern, Margda, Höglund, Kina, Andreasson, Ulf, Wetterberg, Hanna, Börjesson-Hanson, Anne, Blennow, Kaj, Skoog, Ingmar

“…OBJECTIVETo determine the prevalence of preclinical Alzheimer disease (AD) according to current classification systems by examining CSF from a representative…”
Get full text

A Longitudinal Study of the Mini‐Mental State Examination in Late Nonagenarians and Its Relationship with Dementia, Mortality, and Education by Skoog, Johan, Backman, Kristoffer, Ribbe, Mats, Falk, Hanna, Gudmundsson, Pia, Thorvaldsson, Valgeir, Borjesson‐Hanson, Anne, Ostling, Svante, Johansson, Boo, Skoog, Ingmar

“…Objectives To examine level of and change in cognitive status using the Mini‐Mental State Examination (MMSE) in relation to dementia, mortality, education, and…”
Get full text

Calcium supplementation and risk of dementia in women with cerebrovascular disease by Kern, Jürgen, Kern, Silke, Blennow, Kaj, Zetterberg, Henrik, Waern, Margda, Guo, Xinxin, Börjesson-Hanson, Anne, Skoog, Ingmar, Östling, Svante

“…OBJECTIVE:To determine whether calcium supplementation is associated with the development of dementia in women after a 5-year follow-up. METHODS:This was a…”
Get full text

A 9-Year Prospective Population-Based Study on the Association Between the APOEE4 Allele and Late-Life Depression in Sweden by Skoog, Ingmar, Waern, Margda, Duberstein, Paul, Blennow, Kaj, Zetterberg, Henrik, Börjesson-Hanson, Anne, Östling, Svante, Guo, Xinxin, Kern, Jürgen, Gustafson, Deborah, Gudmundsson, Pia, Marlow, Thomas, Kern, Silke

“…Abstract Background It is well established that there is an association between the apolipoprotein E ( APOE ) ε4 allele ( APOE*E4 ) and Alzheimerʼs disease. It…”
Get full text

p75 neurotrophin receptor modulation in mild to moderate Alzheimer disease: a randomized, placebo-controlled phase 2a trial by Shanks, Hayley R. C., Chen, Kewei, Reiman, Eric M., Blennow, Kaj, Cummings, Jeffrey L., Massa, Stephen M., Longo, Frank M., Börjesson-Hanson, Anne, Windisch, Manfred, Schmitz, Taylor W.

“…p75 neurotrophin receptor (p75 NTR ) signaling pathways substantially overlap with degenerative networks active in Alzheimer disease (AD). Modulation of p75…”
Get full text

Higher CSF interleukin-6 and CSF interleukin-8 in current depression in older women. Results from a population-based sample by Kern, Silke, Skoog, Ingmar, Börjesson-Hanson, Anne, Blennow, Kaj, Zetterberg, Henrik, Östling, Svante, Kern, Jürgen, Gudmundsson, Pia, Marlow, Thomas, Rosengren, Lars, Waern, Margda

“…Abstract Objective The literature regarding cerebrospinal fluid (CSF) cytokines in geriatric depression is sparse. The aim of this study was to examine…”
Get full text

Women's ecological oral histories of recycling and development in coastal Yucatán by Hanson, Anne-Marie S.

“…This article addresses the formation of the Chen Kole 'Lob women's recycling cooperative and its relationship to urbanization, plastics consumption, and the…”
Get full text

The Gothenburg MCI study: Design and distribution of Alzheimer’s disease and subcortical vascular disease diagnoses from baseline to 6-year follow-up by Wallin, Anders, Nordlund, Arto, Jonsson, Michael, Lind, Karin, Edman, Åke, Göthlin, Mattias, Stålhammar, Jacob, Eckerström, Marie, Kern, Silke, Börjesson-Hanson, Anne, Carlsson, Mårten, Olsson, Erik, Zetterberg, Henrik, Blennow, Kaj, Svensson, Johan, Öhrfelt, Annika, Bjerke, Maria, Rolstad, Sindre, Eckerström, Carl

“…There is a need for increased nosological knowledge to enable rational trials in Alzheimer’s disease (AD) and related disorders. The ongoing Gothenburg mild…”
Get full text

Relevance of the interplay between amyloid and tau for cognitive impairment in early Alzheimer's disease by Timmers, Maarten, Tesseur, Ina, Bogert, Jennifer, Zetterberg, Henrik, Blennow, Kaj, Börjesson-Hanson, Anne, Baquero, Miquel, Boada, Mercè, Randolph, Christopher, Tritsmans, Luc, Van Nueten, Luc, Engelborghs, Sebastiaan, Streffer, Johannes Rolf

“…Amyloid β (Aβ) and tau are key hallmark features of Alzheimer's disease (AD) neuropathology. The interplay of Aβ and tau for cognitive impairment in early AD…”
Get full text

Pharmacodynamics of atabecestat (JNJ-54861911), an oral BACE1 inhibitor in patients with early Alzheimer's disease: randomized, double-blind, placebo-controlled study by Timmers, Maarten, Streffer, Johannes Rolf, Russu, Alberto, Tominaga, Yushin, Shimizu, Hiroko, Shiraishi, Ayako, Tatikola, Kanaka, Smekens, Pascale, Börjesson-Hanson, Anne, Andreasen, Niels, Matias-Guiu, Jorge, Baquero, Miquel, Boada, Mercè, Tesseur, Ina, Tritsmans, Luc, Van Nueten, Luc, Engelborghs, Sebastiaan

“…β-Secretase enzyme (BACE) inhibition has been proposed as a priority treatment mechanism for Alzheimer's disease (AD), but treatment initiation may need to be…”
Get full text

High-precision U-Pb age and duration of the latest Devonian (Famennian) Hangenberg event, and its implications by Myrow, Paul M., Ramezani, Jahandar, Hanson, Anne E., Bowring, Samuel A., Racki, Grzegorz, Rakociński, Michał

“…Precise U–Pb zircon dates from three volcanic ash beds that bracket the Hangenberg Shale in the Holy Cross Mountains, Poland, constrain the age and duration of…”
Get full text

Women's environmental health activism around waste and plastic pollution in the coastal wetlands of Yucatán by Hanson, Anne-Marie

“…This article focuses on women's grassroots organisations and their role in confronting waste-induced water, health, and development challenges in low-lying…”
Get full text

The Distribution of Apolipoprotein E Genotype Over The Adult Lifespan and in Relation to Country of Birth by Kern, Silke, Mehlig, Kirsten, Kern, Jürgen, Zetterberg, Henrik, Thelle, Dag, Skoog, Ingmar, Lissner, Lauren, Blennow, Kaj, Börjesson-Hanson, Anne

Get full text

Quantitative Vascular Pathology and Phenotyping Familial and Sporadic Cerebral Small Vessel Diseases by Craggs, Lucinda J. L., Hagel, Christian, Kuhlenbaeumer, Gregor, Borjesson-Hanson, Anne, Andersen, Oluf, Viitanen, Matti, Kalimo, Hannu, McLean, Catriona A., Slade, Janet Y., Hall, Roslyn A., Oakley, Arthur E., Yamamoto, Yumi, Deramecourt, Vincent, Kalaria, Rajesh N.

“…We quantified vascular changes in the frontal lobe and basal ganglia of four inherited small vessel diseases (SVDs) including cerebral autosomal dominant…”
Get full text

Five-year mortality in relation to dementia and cognitive function in 95-year-olds by BÖRJESSON-HANSON, Anne, GUSTAFSON, Deborah, SKOOG, Ingmar

“…Dementia is a known predictor of mortality, but most studies include small numbers of participants above age 90. The influence of dementia or cognition on…”
Get full text

Ponezumab in mild-to-moderate Alzheimer's disease: Randomized phase II PET-PIB study by Landen, Jaren W, Andreasen, Niels, Cronenberger, Carol L, Schwartz, Pamela F, Börjesson-Hanson, Anne, Östlund, Henrik, Sattler, Catherine A, Binneman, Brendon, Bednar, Martin M

“…Abstract Background The safety, pharmacokinetics, and effect on peripheral and central amyloid beta (Aβ) of multiple doses of ponezumab, an anti-Aβ monoclonal…”
Get full text

DSM-IV and DSM-5 Prevalence of Social Anxiety Disorder in a Population Sample of Older People by Karlsson, Björn, M.D., Ph.D, Sigström, Robert, M.D., Ph.D, Östling, Svante, M.D., Ph.D, Waern, Margda, M.D., Ph.D, Börjesson-Hanson, Anne, M.D., Ph.D, Skoog, Ingmar, M.D., Ph.D

“…Objectives To examine the prevalence of social anxiety disorders (SAD) with (DSM-IV) and without (DSM-5) the person's own assessment that the fear was…”
Get full text

MRI characteristics and scoring in HDLS due to CSF1R gene mutations by SUNDAL, Christina, VAN GERPEN, Jay A, BORJESSON-HANSON, Anne, TSELIS, Alex, SWERDLOW, Russell H, MILLER, Bradley B, FUJIOKA, Shinsuke, HECKMAN, Michael G, UITTI, Ryan J, JOSEPHS, Keith A, BAKER, Matt, ANDERSEN, Oluf, NICHOLSON, Alexandra M, RADEMAKERS, Rosa, DICKSON, Dennis W, BRODERICK, Daniel, WSZOLEK, Zbigniew K, WIDER, Christian, SHUSTER, Elizabeth A, AASLY, Jan, SPINA, Salvatore, GHETTI, Bernardino, ROEBER, Sigrun, GARBERN, James

“…To describe the brain MRI characteristics of hereditary diffuse leukoencephalopathy with spheroids (HDLS) with known mutations in the colony-stimulating factor…”
Get full text