Search Results - "Hansler, Alex"

Protein nitrotryptophan: Formation, significance and identification by Nuriel, Tal, Hansler, Alex, Gross, Steven S.

“…Reactive nitrogen species are formed during a variety of disease states and have been shown to modify several amino acids on proteins. To date, the majority of…”
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Untargeted metabolite profiling reveals that nitric oxide bioynthesis is an endogenous modulator of carotenoid biosynthesis in Deinococcus radiodurans and is required for extreme ionizing radiation resistance by Hansler, Alex, Chen, Qiuying, Ma, Yuliang, Gross, Steven S.

“…Deinococcus radiodurans (Drad) is the most radioresistant organism known. Although mechanisms that underlie the extreme radioresistance of Drad are…”
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LRP6 exerts non-canonical effects on Wnt signaling during neural tube closure by Gray, Jason D, Kholmanskikh, Stanislav, Castaldo, Bozena S, Hansler, Alex, Chung, Heekyung, Klotz, Brian, Singh, Shawn, Brown, Anthony M C, Ross, M Elizabeth

“…Low-density lipoprotein receptor related protein 6 (Lrp6) mutational effects on neurulation were examined using gain (Crooked tail, Lrp6(Cd)) and loss…”
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KCNQ1, KCNE2, and Na+-coupled solute transporters form reciprocally regulating complexes that affect neuronal excitability by Abbott, Geoffrey W, Tai, Kwok-Keung, Neverisky, Daniel L, Hansler, Alex, Hu, Zhaoyang, Roepke, Torsten K, Lerner, Daniel J, Chen, Qiuying, Liu, Li, Zupan, Bojana, Toth, Miklos, Haynes, Robin, Huang, Xiaoping, Demirbas, Didem, Buccafusca, Roberto, Gross, Steven S, Kanda, Vikram A, Berry, Gerard T

“…Na(+)-coupled solute transport is crucial for the uptake of nutrients and metabolic precursors, such as myo-inositol, an important osmolyte and precursor for…”
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A requirement for Gch1 and tetrahydrobiopterin in embryonic development by Douglas, Gillian, Hale, Ashley B., Crabtree, Mark J, Ryan, Brent J., Hansler, Alex, Watschinger, Katrin, Gross, Steven S, Lygate, Craig A., Alp, Nicholas J., Channon, Keith M.

“…GTP cyclohydrolase I (GTPCH) catalyses the first and rate-limiting reaction in the synthesis of the enzymatic cofactor, tetrahydrobiopterin (BH4). Loss of…”
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Protein nitrotryptophan: Formation, significance and identification: Redox Proteomics by NURIEL, Tal, HANSLER, Alex, GROSS, Steven S

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Endogenous nitric oxide production in the radioresistant bacterium deinococcus radiodurans determines lipid composition and is essential for rapid growth recovery after gamma-irradiation by Hansler, Alex, Chen, Qiuying, Crane, Brian, Gross, Steven

“…The eubacteria Deinococcus radiodurans (Drad) is the most radioresistant organism known. The extreme radioresistance of Drad primarily owes to its efficiency…”
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Untargeted metabolite profiling of murine embryos to reveal metabolic perturbations associated with neural tube closure defects by Hansler, Alex, Chen, Qiuying, Gray, Jason D., Ross, M. Elizabeth, Finnell, Richard H., Gross, Steven S.

“…Background Neural tube closure defects (NTDs) are among the most common congenital malformation in human, typically presenting in liveborns as spina bifida. At…”
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Untargeted metabolomics to assess metabolic consequences of gene mutations in early stage murine embryos and bacteria by Hansler, Alex Robert

“…Metabolomics, the study of small molecule metabolites, is an emerging "omics" field that defines one of the major next-generation approaches in systems…”
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