Search Results - "Hansen Haugsten, Marie"
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Myocardial oxidative stress is increased in early reperfusion, but systemic antioxidative therapy does not prevent ischemia-reperfusion arrhythmias in pigs
Published in Frontiers in cardiovascular medicine (26-09-2023)“…BackgroundArrhythmias in the early phase of reperfusion after myocardial infarction (MI) are common, and can lead to hemodynamic instability or even cardiac…”
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Increased dosage of DYRK1A leads to congenital heart defects in a mouse model of Down syndrome
Published in Science translational medicine (24-01-2024)“…Down syndrome (DS) is caused by trisomy of human chromosome 21 (Hsa21). DS is a gene dosage disorder that results in multiple phenotypes including congenital…”
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Exercise Training Stabilizes RyR2-Dependent Ca2+ Release in Post-infarction Heart Failure
Published in Frontiers in cardiovascular medicine (25-01-2021)“…Aim: Dysfunction of the cardiac ryanodine receptor (RyR2) is an almost ubiquitous finding in animal models of heart failure (HF) and results in abnormal Ca 2+…”
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Abstract 11558: The Role of Oxidized CaMKII in Early Ischemia-Reperfusion Triggered Ventricular Arrhythmias
Published in Circulation (New York, N.Y.) (16-11-2021)“…IntroductionArrhythmias can complicate revascularization procedures after transmural infarctions and induce hemodynamic instability, but most cases can be…”
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CaMKII and reactive oxygen species contribute to early reperfusion arrhythmias, but oxidation of CaMKIIδ at methionines 281/282 is not a determining factor
Published in Journal of molecular and cellular cardiology (2022)“…Background Available evidence suggest that Ca2+/calmodulin-dependent protein kinase type IIδ (CaMKIIδ) and reactive oxygen species (ROS) are important in early…”
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CaMKII and reactive oxygen species contribute to early reperfusion arrhythmias, but oxidation of CaMKIIδ at methionines 281/282 is not a determining factor
Published in Journal of molecular and cellular cardiology (01-02-2023)“…Available evidence suggest that Ca2+/calmodulin-dependent protein kinase type IIδ (CaMKIIδ) and reactive oxygen species (ROS) are important in early…”
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Abstract P2052: Lowered Pro-fibrotic And Damage Associated Molecular Pattern Gene Expressions After Exercise Training In A Mouse Model Of Hypertrophic Cardiomyopathy
Published in Circulation research (05-08-2022)“…BackgroundHypertrophic cardiomyopathy (HCM) is the most frequent inherited cardiac disease, most often caused by mutations in sarcomere genes. The disease is…”
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β-catenin promotes endothelial survival by regulating eNOS activity and flow-dependent anti-apoptotic gene expression
Published in Cell death & disease (30-06-2020)“…Increased endothelial cell (EC) apoptosis is associated with the development of atherosclerotic plaques that develop predominantly at sites exposed to…”
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Exercise Training Stabilizes RyR2-Dependent Ca 2+ Release in Post-infarction Heart Failure
Published in Frontiers in cardiovascular medicine (2020)“…Dysfunction of the cardiac ryanodine receptor (RyR2) is an almost ubiquitous finding in animal models of heart failure (HF) and results in abnormal Ca release…”
Get full text
Journal Article