Search Results - "Hansen, Torben Frøstrup"

The Prognostic Importance of ctDNA in Rectal Cancer: A Critical Reappraisal by Dizdarevic, Edina, Hansen, Torben Frøstrup, Jakobsen, Anders

“…The treatment of locally advanced rectal cancer (LARC) has evolved during the last decades, but recurrence remains a problem. Circulating tumor DNA (ctDNA) may…”
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Prognostic impact of CDX2 in stage II colon cancer: results from two nationwide cohorts by Hansen, Torben Frøstrup, Kjær-Frifeldt, Sanne, Eriksen, Ann Christina, Lindebjerg, Jan, Jensen, Lars Henrik, Sørensen, Flemming Brandt, Jakobsen, Anders

“…Background The aim of the present study was to validate the prognostic impact of CDX2 in patients with stage II colon cancer. Methods Two unbiased…”
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Randomized Phase II trial of combination chemotherapy with panitumumab or bevacizumab for patients with inoperable biliary tract cancer without KRAS exon 2 mutations by Amin, Nadia Emad Lotfi, Hansen, Torben Frøstrup, Fernebro, Eva, Ploen, John, Eberhard, Jakob, Lindebjerg, Jan, Jensen, Lars Henrik

“…Biliary tract cancers (BTC) are rare and often diagnosed in late stages with advanced, nonresectable disease. The targeted agents panitumumab and bevacizumab…”
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Drug Repositioning Based on the Reversal of Gene Expression Signatures Identifies TOP2A as a Therapeutic Target for Rectal Cancer by Carvalho, Robson Francisco, do Canto, Luisa Matos, Cury, Sarah Santiloni, Frøstrup Hansen, Torben, Jensen, Lars Henrik, Rogatto, Silvia Regina

“…Rectal cancer is a common disease with high mortality rates and limited therapeutic options. Here we combined the gene expression signatures of rectal cancer…”
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Precision medicine applied to metastatic colorectal cancer using tumor-derived organoids and in-vitro sensitivity testing: a phase 2, single-center, open-label, and non-comparative study by Jensen, Lars Henrik, Rogatto, Silvia Regina, Lindebjerg, Jan, Havelund, Birgitte, Abildgaard, Cecilie, do Canto, Luisa Matos, Vagn-Hansen, Chris, Dam, Claus, Rafaelsen, Søren, Hansen, Torben Frøstrup

“…Patients with colorectal metastatic disease have a poor prognosis, limited therapeutic options, and frequent development of resistance. Strategies based on…”
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Methylated Circulating Tumor DNA in Blood as a Tool for Diagnosing Lung Cancer: A Systematic Review and Meta-Analysis by Borg, Morten, Wen, Sara Witting Christensen, Andersen, Rikke Fredslund, Timm, Signe, Hansen, Torben Frøstrup, Hilberg, Ole

“…Lung cancer is the leading cause of cancer-related deaths, and early detection is crucial for improving patient outcomes. Current screening methods using…”
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A novel mesenchymal‐associated transcriptomic signature for risk‐stratification and therapeutic response prediction in colorectal cancer by Matsuyama, Takatoshi, Kandimalla, Raju, Ishikawa, Toshiaki, Takahashi, Naoki, Yamada, Yasuhide, Yasuno, Masamichi, Kinugasa, Yusuke, Hansen, Torben Frøstrup, Fakih, Marwan, Uetake, Hiroyuki, Győrffy, Balázs, Goel, Ajay

“…Risk stratification in Stage II and III colorectal cancer (CRC) patients is critical, as it allows patient selection for adjuvant chemotherapy. In view of the…”
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Soluble programmed death ligand 1 as prognostic biomarker in non-small cell lung cancer patients receiving nivolumab, pembrolizumab or atezolizumab therapy by Brun, Sinne Søberg, Hansen, Torben Frøstrup, Wen, Sara Witting Christensen, Nyhus, Christa Haugaard, Bertelsen, Lisbeth, Jakobsen, Anders, Hansen, Torben Schjødt, Nederby, Line

“…Many studies have focused on the prognostic role of soluble programmed death ligand 1 (sPD-L1) in non-small cell lung cancer (NSCLC), but outcomes are…”
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Methylated Cell-Free Tumor DNA in Sputum as a Tool for Diagnosing Lung Cancer-A Systematic Review and Meta-Analysis by Wen, Sara Witting Christensen, Borg, Morten, Timm, Signe, Hansen, Torben Frøstrup, Hilberg, Ole, Andersen, Rikke Fredslund

“…Lung cancer is the leading cause of cancer-related mortality worldwide. Early diagnosis is pivotal for the prognosis. There is a notable overlap between lung…”
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NPY Gene Methylation in Circulating Tumor DNA as an Early Biomarker for Treatment Effect in Metastatic Colorectal Cancer by Raunkilde, Louise, Hansen, Torben Frøstrup, Andersen, Rikke Fredslund, Havelund, Birgitte Mayland, Thomsen, Caroline Brenner, Jensen, Lars Henrik

“…Despite several limitations, the Response Evaluation Criteria in Solid Tumors version 1.1 (RECIST 1.1) are still the gold standard in response evaluation of…”
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Non-Curative Treatment Choices in Colorectal Cancer: Predictors and Between-Hospital Variations in Denmark: A Population-Based Register Study by Rattenborg, Søren, Frøstrup Hansen, Torben, Möller, Sören, Frostberg, Erik, Rahr, Hans Bjarke

“…Variations in treatment choices have been reported in colorectal cancer (CRC). In the context of national recommendations, we aimed to elucidate predictors and…”
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MicroRNA-200b is downregulated in colon cancer budding cells by Knudsen, Kirsten Nguyen, Lindebjerg, Jan, Nielsen, Boye Schnack, Hansen, Torben Frøstrup, Sørensen, Flemming Brandt

“…The microRNA-200 (miR-200) family acts as a major suppressor of epithelial-mesenchymal transition (EMT). Impaired miR-200 expression may lead to EMT initiation…”
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microRNA-17 Is the Most Up-Regulated Member of the miR-17-92 Cluster during Early Colon Cancer Evolution by Knudsen, Kirsten Nguyen, Nielsen, Boye Schnack, Lindebjerg, Jan, Hansen, Torben Frøstrup, Holst, René, Sørensen, Flemming Brandt

“…Deregulated microRNAs play a role in the development and progression of colon cancer, but little is known about their tissue and cell distribution in the…”
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Study protocol: fish oil supplement in prevention of oxaliplatin-induced peripheral neuropathy in adjuvant colorectal cancer patients - a randomized controlled trial. (OxaNeuro) by Gehr, Nina Lykkegaard, Karlsson, Páll, Timm, Signe, Christensen, Signe, Hvid, Christian Andreas, Peric, Jana, Hansen, Torben Frøstrup, Lauritzen, Lotte, Finnerup, Nanna Brix, Ventzel, Lise

“…Oxaliplatin-induced peripheral neuropathy (OIPN) in general and painful OIPN in particular is a debilitating late effect that severely affects cancer…”
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Identification of patients' smoking status using an explainable AI approach: a Danish electronic health records case study by Ebrahimi, Ali, Henriksen, Margrethe Bang Høstgaard, Brasen, Claus Lohman, Hilberg, Ole, Hansen, Torben Frøstrup, Jensen, Lars Henrik, Peimankar, Abdolrahman, Wiil, Uffe Kock

“…Smoking is a critical risk factor responsible for over eight million annual deaths worldwide. It is essential to obtain information on smoking habits to…”
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Missingness mechanisms and generalizability of patient reported outcome measures in colorectal cancer survivors - assessing the reasonableness of the "missing completely at random" assumption by Lyhne, Johanne Dam, Smith, Allan 'Ben', Jensen, Lars Henrik, Hansen, Torben Frøstrup, Frostholm, Lisbeth, Timm, Signe

“…Patient-Reported Outcome Measures (PROM) provide important information, however, missing PROM data threaten the interpretability and generalizability of…”
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Cell Free Methylated Tumor DNA in Bronchial Lavage as an Additional Tool for Diagnosing Lung Cancer-A Systematic Review by Wen, Sara Witting Christensen, Wen, Jan, Hansen, Torben Frøstrup, Jakobsen, Anders, Hilberg, Ole

“…This systematic review investigated circulating methylated tumor DNA in bronchial lavage fluid for diagnosing lung cancer. PROSPERO registration…”
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miR-21 expression analysis in budding colon cancer cells by confocal slide scanning microscopy by Knudsen, Kirsten Nguyen, Lindebjerg, Jan, Kalmár, Alexandra, Molnár, Béla, Sørensen, Flemming Brandt, Hansen, Torben Frøstrup, Nielsen, Boye Schnack

“…MicroRNA-21 (miR-21) expression in stromal fibroblastic cells in colorectal cancer is well-documented, whereas miR-21 expression in tumor budding cells (TBCs)…”
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Heterogeneity of miRNA expression in localized prostate cancer with clinicopathological correlations by Zedan, Ahmed Hussein, Blavnsfeldt, Søren Garm, Hansen, Torben Frøstrup, Nielsen, Boye Schnack, Marcussen, Niels, Pleckaitis, Mindaugas, Osther, Palle Jörn Sloth, Sørensen, Flemming Brandt

“…In the last decade microRNAs (miRNAs) have been widely investigated in prostate cancer (PCa) and have shown to be promising biomarkers in diagnostic,…”
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CT and 3 Tesla MRI in the TN Staging of Colon Cancer: A Prospective, Blind Study by Rafaelsen, Søren R, Dam, Claus, Vagn-Hansen, Chris, Møller, Jakob, Rahr, Hans B, Sjöström, Mikkel, Lindebjerg, Jan, Hansen, Torben Frøstrup, Pedersen, Malene Roland Vils

“…(1) Background: Computer tomography (CT) scanning is currently the standard method for staging of colon cancer; however, the CT based preoperative local…”
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