Search Results - "Hansen, Peter J."

Effects of heat stress on mammalian reproduction by Hansen, Peter J.

“…Heat stress can have large effects on most aspects of reproductive function in mammals. These include disruptions in spermatogenesis and oocyte development,…”
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Prospects for gene introgression or gene editing as a strategy for reduction of the impact of heat stress on production and reproduction in cattle by Hansen, Peter J.

“…In cattle, genetic variation exists in regulation of body temperature and stabilization of cellular function during heat stress. There are opportunities to…”
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Reproductive physiology of the heat-stressed dairy cow: implications for fertility and assisted reproduction by Hansen, Peter J

“…Heat stress causes a large decline in pregnancy success per insemination during warm times of the year. Improvements in fertility are possible by exploiting…”
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Review: Some challenges and unrealized opportunities toward widespread use of the in vitro-produced embryo in cattle production by Hansen, Peter J

“…The embryo produced by in vitro oocyte maturation, fertilization, and embryonic development is an important resource for genetic improvement and has the…”
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Uterine influences on conceptus development in fertility-classified animals by Moraes, Joao G. N., Behura, Susanta K., Geary, Thomas W., Hansen, Peter J., Neibergs, Holly L., Spencer, Thomas E.

“…A major unresolved issue is how the uterus influences infertility and subfertility in cattle. Serial embryo transfer was previously used to classify heifers as…”
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Current and future assisted reproductive technologies for mammalian farm animals by Hansen, Peter J

“…Reproduction in domestic animals is under control by man and the technologies developed to facilitate that control have a major impact on the efficiency of…”
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Genome-Wide Association Mapping for Identification of Quantitative Trait Loci for Rectal Temperature during Heat Stress in Holstein Cattle by Dikmen, Serdal, Cole, John B, Null, Daniel J, Hansen, Peter J, Moore, Stephen

“…Heat stress compromises production, fertility, and health of dairy cattle. One mitigation strategy is to select individuals that are genetically resistant to…”
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Postnatal phenotype of dairy cows is altered by in vitro embryo production using reverse X-sorted semen by Siqueira, Luiz G B, Dikmen, Serdal, Ortega, M Sofia, Hansen, Peter J

“…Abnormal fetuses, neonates, and adult offspring derived by assisted reproductive technologies have been reported in humans and mice and have been associated…”
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Single-cell gene expression of the bovine blastocyst by Negrón-Pérez, Verónica M, Zhang, Yanping, Hansen, Peter J

“…The first two differentiation events in the embryo result in three cell types – epiblast, trophectoderm (TE) and hypoblast. The purpose here was to identify…”
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Development of a formula for scoring competence of bovine embryos to sustain pregnancy by Rabaglino, Maria Belen, Hansen, Peter J.

“…Embryo transfer in cattle and other species is a key reproductive technology to improve genetic merit. However, pregnancy loss after embryo transfer is still a…”
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Role of yes-associated protein 1, angiomotin, and mitogen-activated kinase kinase 1/2 in development of the bovine blastocyst by Negrón-Pérez, Verónica M, Hansen, Peter J

“…The morula-stage embryo is transformed into a blastocyst composed of epiblast, hypoblast, and trophectoderm (TE) through mechanisms that, in the mouse, involve…”
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The WNT signaling antagonist Dickkopf‐1 directs lineage commitment and promotes survival of the preimplantation embryo by Denicol, Anna C., Block, Jeremy, Kelley, Dale E., Pohler, Ky G., Dobbs, Kyle B., Mortensen, Christopher J., Ortega, M. Sofia, Hansen, Peter J.

“…Successful embryonic development is dependent on factors secreted by the reproductive tract. Dickkopf‐1 (DKK1), an antagonist of the wingless‐related mouse…”
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RhoA/ROCK signaling antagonizes bovine trophoblast stem cell self-renewal and regulates preimplantation embryo size and differentiation by Pillai, Viju Vijayan, Kei, Tiffany G, Gurung, Shailesh, Das, Moubani, Siqueira, Luiz G B, Cheong, Soon Hon, Hansen, Peter J, Selvaraj, Vimal

“…Exponential proliferation of trophoblast stem cells (TSC) is crucial in Ruminantia to maximize numerical access to caruncles, the restricted uterine sites that…”
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Dynamics of DNA methylation during early development of the preimplantation bovine embryo by Dobbs, Kyle B, Rodriguez, Marlon, Sudano, Mateus J, Ortega, M Sofia, Hansen, Peter J

“…There is species divergence in control of DNA methylation during preimplantation development. The exact pattern of methylation in the bovine embryo has not…”
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Loci and pathways associated with uterine capacity for pregnancy and fertility in beef cattle by Neupane, Mahesh, Geary, Thomas W, Kiser, Jennifer N, Burns, Gregory W, Hansen, Peter J, Spencer, Thomas E, Neibergs, Holly L

“…Infertility and subfertility negatively impact the economics and reproductive performance of cattle. Of note, significant pregnancy loss occurs in cattle…”
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WNT regulation of embryonic development likely involves pathways independent of nuclear CTNNB1 by Tribulo, Paula, Moss, James I, Ozawa, Manabu, Jiang, Zongliang, Tian, Xiuchun (Cindy), Hansen, Peter J

“…The bovine was used to examine the potential for WNT signaling to affect the preimplantation embryo. Expression of seven key genes involved in canonical WNT…”
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The incompletely fulfilled promise of embryo transfer in cattle—why aren’t pregnancy rates greater and what can we do about it? by Hansen, Peter J

“…Abstract Typically, bovine embryos are transferred into recipient females about day 7 after estrus or anticipated ovulation, when the embryo has reached the…”
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Genetic variation in resistance of the preimplantation bovine embryo to heat shock by Hansen, Peter J

“…Reproduction is among the physiological functions in mammals most susceptible to disruption by hyperthermia. Many of the effects of heat stress on function of…”
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Physiological responses of Holstein calves and heifers carrying the SLICK1 allele to heat stress in California and Florida dairy farms by Carmickle, Allie T., Larson, Colleen C., Hernandez, Froylan Sosa, Pereira, Jessica M.V., Ferreira, Fernanda C., Haimon, McKenzie L.J., Jensen, Laura M., Hansen, Peter J., Denicol, Anna C.

“…Inheritance of the SLICK1 allele of the prolactin receptor gene improves thermotolerance of lactating Holstein cows under humid heat stress conditions. The aim…”
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Sex and the preimplantation embryo: implications of sexual dimorphism in the preimplantation period for maternal programming of embryonic development by Hansen, Peter J, Dobbs, Kyle B, Denicol, Anna C, Siqueira, Luiz G. B

“…The developmental program of the embryo displays a plasticity that can result in long-acting effects that extend into postnatal life. In mammals, adult…”
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