Search Results - "Hansen, Pernille B Laerkegaard"

Aldosterone Induces Vasoconstriction in Individuals with Type 2 Diabetes: Effect of Acute Antioxidant Administration by Finsen, Stine Høyer, Hansen, Mie Rytz, Hansen, Pernille B Lærkegaard, Mortensen, Stefan P

“…Abstract Context Individuals with type 2 diabetes have an increased risk of endothelial dysfunction and cardiovascular disease. Plasma aldosterone could…”
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Thrombin Inhibition Prevents Endothelial Dysfunction and Reverses 20-HETE Overproduction without Affecting Blood Pressure in Angiotensin II-Induced Hypertension in Mice by Kij, Agnieszka, Bar, Anna, Przyborowski, Kamil, Proniewski, Bartosz, Mateuszuk, Lukasz, Jasztal, Agnieszka, Kieronska-Rudek, Anna, Marczyk, Brygida, Matyjaszczyk-Gwarda, Karolina, Tworzydlo, Anna, Enggaard, Camilla, Hansen, Pernille B. Lærkegaard, Jensen, Boye, Walczak, Maria, Chlopicki, Stefan

“…Angiotensin II (Ang II) induces hypertension and endothelial dysfunction, but the involvement of thrombin in these responses is not clear. Here, we assessed…”
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Macula Densa Nitric Oxide Synthase 1β Protects against Salt-Sensitive Hypertension by Lu, Yan, Wei, Jin, Stec, David E, Roman, Richard J, Ge, Ying, Cheng, Liang, Liu, Eddie Y, Zhang, Jie, Hansen, Pernille B Laerkegaard, Fan, Fan, Juncos, Luis A, Wang, Lei, Pollock, Jennifer, Huang, Paul L, Fu, Yiling, Wang, Shaohui, Liu, Ruisheng

“…Nitric oxide (NO) is an important negative modulator of tubuloglomerular feedback responsiveness. We recently found that macula densa expresses α-, β-, and…”
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Oxidised IL-33 Mediates Proximal Tubular Injury Through the RAGE/EGFR Pathway: FR-PO349 by Marin, Elena Liarte, Musial, Barbara, Bousfield, Philip M., Seth, Asha, Hansen, Pernille B. Laerkegaard, Woollard, Kevin

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TWEAK-Fn14 Signalling in Mesangial Cells Drives Intrarenal Inflammation During CKD Progression: TH-PO891 by Seth, Asha, Musial, Barbara, Haschler, Timo N., Wang, Hong, Laerkegaard Hansen, Pernille B.

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RXFP1, the Relaxin Receptor, Is a Therapeutic Target Expressed in the Human Kidney, Not Rodent: SA-PO270 by Lal, Mark, Eddy, Sean, Hodgin, Jeffrey B., Althage, Magnus, Hansen, Pernille B. Laerkegaard, Patrakka, Jaakko, Kretzler, Matthias

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SGLT2 Inhibition Mitigates Intravascular Fluid Retention Driven by an Endothelin A Receptor Antagonist: PUB361 by Menzies, Robert I., Veenit, Vandana, Ahlström, Christine, Greasley, Peter J., Skrtic, Stanko, Kohan, Donald E., Laerkegaard Hansen, Pernille B.

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NLRP3 Inflammasome Inhibition Decreases NETosis in AKI: FR-PO167 by Tomaz, David C., Seth, Asha, Parsons, Ricardo, Irving, Lorraine M., Miller, Lorraine, Laerkegaard Hansen, Pernille B., Woollard, Kevin

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Lipid Metabolic Profiling of Ex Vivo Isolated Glomeruli as a Screening Platform for Modelling Glomerular Metabolic Dysfunction During Renal Disease: PO0630 by Romoli, Simone, Krause, Fynn N., Griffin, Julian L., Laerkegaard Hansen, Pernille B., Woollard, Kevin

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Human Induced Pluripotent Stem Cell-Derived Kidney Micro-Organoids for High Throughput Disease Modeling in Drug Discovery: PO0613 by Kumar, Santhosh V, Jonebring, Anna, Laerkegaard Hansen, Pernille B., Hicks, Ryan, Woollard, Kevin

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In Vivo Data to Support Induced Pluripotent Stem Cell-Derived Renal Progenitors as Potential Cell Therapy for Kidney Disease: PO0635 by Woollard, Kevin, Gruber, Ralph, Jonebring, Anna, Svensson, Anna K., Marin, Elena Liarte, Dahlqvist, Ulrika, Hicks, Ryan, Laerkegaard Hansen, Pernille B.

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Physiological Replication of the Glomerulus Using a Triple Culture Microphysiological System: PO0510 by Pajoumshariati, Seyedramin, Ewart, Lorna, Luc, Raymond, Kujala, Ville J., Peel, Samantha, Weber, Heather, Laerkegaard Hansen, Pernille B., Williams, Julie

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Overexpression of Adiponectin, via an Adipocyte Specific Promoter, Confers Metabolic Benefits and Transient Improvements in Urine Albumin-Creatinine Ratio (UACR): FR-PO373 by Seth, Asha, Liljeblad, Mathias, Haschler, Timo N., Tonelius, Pernilla, Choi, Su Mi, Marin, Elena Liarte, Bousfield, Philip M., Kurasawa, James H., Duran, Esther Nuñez, Basak, Jayati, Boianelli, Alessandro, Svenningsen, Per, Hansen, Pernille B. Laerkegaard, Williams, Julie, Ikeda, Yasuhiro

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MiR-200b Induces ZEB1-Mediated Upregulation of Matriptase and Affects Expression of Podocin: A Proposed Mechanism of Podocyte Effacement and Proteinuria in Diabetic Kidney Disease: SA-PO407 by Tati, Ramesh, Müller-Deile, Janina, Walentinsson, Anna, Sopel, Nina, Carracedo, Miguel, Lassen, Emelie, Ebefors, Kerstin, Soderberg, Magnus, Daniel, Christoph, Hansen, Pernille B. Laerkegaard, Schiffer, Mario, Nystrom, Jenny C., Buvall, Lisa

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A 3D Vascularised Tubule Model Improves the Phenotype of Cultured Cells: PO0492 by Carracedo, Miguel, Robinson, Sanlin, Alaei, Babak, Clausen, Maryam, Hicks, Ryan, Belfield, Graham P., Bak, Annette, Lewis, Jennifer A., Laerkegaard Hansen, Pernille B., Williams, Julie

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Transcriptional Profiling of Renal Endothelial Compartments During Progression of Murine Diabetic Nephropathy: PO0661 by Zhou, Alex X., Jeansson, Marie, He, Liqun, Tonelius, Pernilla, Muhl, Lars, Uhrbom, Martin, Liu, Jianping, Granqvist, Anna, Lerman, Lilach O., Betsholtz, Christer, Laerkegaard Hansen, Pernille B.

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Investigating Lysozyme as a Mediator of Tubular Epithelial Inflammation: An Example of CKD Knowledge Graph Target Discovery and Validation: FR-PO1008 by Woollard, Kevin, Musial, Barbara, Nilsson, Karolina A., Marin, Elena Liarte, Buvall, Lisa, MacPhee, Iain, Ryaboshapkina, Maria, Kirik, Ufuk, Paul, Dirk S., Bohlooly, Mohammad, Taddei, Andrea, Rolando, Delphine M., Mori, Andres, Bendtsen, Claus, Laerkegaard Hansen, Pernille B.

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Investigating Mesenchymal Stem Cell Sources for VEGFA mRNA Transfection and In Vivo Protein Exposure: PUB083 by Menzies, Robert I., Graneli, Cecilia, Zhou, Alex X., Hong, Xuechong, Dahlqvist, Ulrika, Vaithilingam, Vijayaganapathy, Hölttä, Mikko, Henderson, Neil, Bates, Stephanie M., Fellows, Mick D., Forslöw, Anna, Zhu, Xiang yang, Ahlström, Christine, Boianelli, Alessandro, Hicks, Ryan, Lerman, Lilach O., Hansen, Pernille B. Laerkegaard

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Renal Cytosolic Phospholipase A2 Mediates AKI in Humans: PO0274 by Asowata, Evans O., Krause, Fynn N., Romoli, Simone, Ling, Stephanie, Tan, Jennifer Y., Musial, Barbara, Huang, Margaret M., Mahbubani, Krishnaa T., Griffin, Julian L., Laerkegaard Hansen, Pernille B., Saeb-Parsy, Kourosh, Woollard, Kevin

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IL-33 as a Novel Target for the Treatment of Diabetic Kidney Disease: PO0645 by Musial, Barbara, Seth, Asha, Baker, David J., Heasman, Stephanie C., Conway, James, Slidel, Tim, Wang, Xiaozhen J., Ryden-Bergsten, Tina, Laerkegaard Hansen, Pernille B., Woollard, Kevin, Marin, Elena Liarte

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