Search Results - "Hansen, Paul Robert"
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Review on Abyssomicins: Inhibitors of the Chorismate Pathway and Folate Biosynthesis
Published in Molecules (Basel, Switzerland) (06-06-2018)“…Antifolates targeting folate biosynthesis within the shikimate-chorismate-folate metabolic pathway are ideal and selective antimicrobials, since higher…”
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Peptide Antibody Reactivity to Homologous Regions in Glutamate Decarboxylase Isoforms and Coxsackievirus B4 P2C
Published in International journal of molecular sciences (17-04-2022)“…Two isoforms of the glutamate decarboxylase (GAD) enzyme exist, GAD65 and GAD67, which are associated with type 1 diabetes (T1D) and stiff-person syndrome…”
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Structure Elucidation of Prenyl- and Geranyl-Substituted Coumarins in Gerbera piloselloides by NMR Spectroscopy, Electronic Circular Dichroism Calculations, and Single Crystal X-ray Crystallography
Published in Molecules (Basel, Switzerland) (08-04-2020)“…Crude ethyl acetate extract of (L.) Cass. was investigated by dual high-resolution PTP1B/α-glucosidase inhibition profiling and LC-PDA-HRMS. This indicated the…”
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Contribution of Peptide Backbone to Anti-Citrullinated Peptide Antibody Reactivity
Published in PloS one (10-12-2015)“…Rheumatoid arthritis (RA) is one of the most common autoimmune diseases, affecting approximately 1-2% of the world population. One of the characteristic…”
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Production and Characterization of Peptide Antibodies to the C-Terminal of Frameshifted Calreticulin Associated with Myeloproliferative Diseases
Published in International journal of molecular sciences (18-06-2022)“…Myeloproliferative Neoplasms (MPNs) constitute a group of rare blood cancers that are characterized by mutations in bone marrow stem cells leading to the…”
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Linear peptidomimetics as potent antagonists of Staphylococcus aureus agr quorum sensing
Published in Scientific reports (23-02-2018)“…Staphylococcus aureus is an important pathogen causing infections in humans and animals. Increasing problems with antimicrobial resistance has prompted the…”
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Recent advances in the development of antimicrobial peptides against ESKAPE pathogens
Published in Heliyon (15-06-2024)“…Multi-drug resistant ESKAPE pathogens (Enterococcus faecium, Staphylococcus aureus, Klebsiella pneumoniae, Acinetobacter baumannii, Pseudomonas aeruginosa, and…”
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Fluorescent Analogues of Human α-Calcitonin Gene-Related Peptide with Potent Vasodilator Activity
Published in International journal of molecular sciences (17-02-2020)“…Human α-calcitonin gene-related peptide (h-α-CGRP) is a highly potent vasodilator peptide that belongs to the family of calcitonin peptides. There are two…”
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Reactivity of Rheumatoid Arthritis-Associated Citrulline-Dependent Antibodies to Epstein-Barr Virus Nuclear Antigen1-3
Published in Antibodies (Basel) (11-03-2022)“…Rheumatoid arthritis (RA) is a chronic disease which causes joint inflammation and, ultimately, erosion of the underlying bone. Diagnosis of RA is based on the…”
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Specificity of Anti-Citrullinated Protein Antibodies to Citrullinated α-Enolase Peptides as a Function of Epitope Structure and Composition
Published in Antibodies (Basel) (21-07-2021)“…Rheumatoid arthritis (RA) is an autoimmune disease affecting approximately 1–2% of the world population. In addition to the first discovered serologic markers…”
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Synthesis of Peptoids Containing Multiple Nhtrp and Ntrp Residues: A Comparative Study of Resin, Cleavage Conditions and Submonomer Protection
Published in Frontiers in chemistry (29-04-2020)“…Peptoids hold status as peptide-mimetics with versatile biological applications due to their proteolytic stability and structural diversity. Among those that…”
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Cyclic peptide inhibitors of the β-sliding clamp in Staphylococcus aureus
Published in PloS one (04-09-2013)“…Interaction between pairs of Staphylococcus aureus replication proteins was detected in an Escherichia coli based two-hybrid analysis. A reverse two-hybrid…”
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Cyclic N-locked indolicidin analogues with antimicrobial activity: Effect of ring size and fatty acid acylation
Published in European journal of medicinal chemistry reports (01-12-2022)“…Novel antimicrobial drugs are in high demand due to the increasing emergence of multi-drug resistant bacteria. In recent years, much attention has been given…”
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Correlation between centromere protein-F autoantibodies and cancer analyzed by enzyme-linked immunosorbent assay
Published in Molecular cancer (26-08-2013)“…Centromere protein-F (CENP-F) is a large nuclear protein of 367 kDa, which is involved in multiple mitosis-related events such as proper assembly of the…”
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Fine mapping of a monoclonal antibody to the N-Methyl D-aspartate receptor reveals a short linear epitope
Published in Biopolymers (2012)“…Anti‐N‐Methyl D‐aspartate receptor encephalitis is an autoimmune disease in which autoantibodies are produced against extracellular regions of the N‐Methyl…”
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Antigenic Profiling of a Chlamydia trachomatis Gene-Expression Library
Published in The Journal of infectious diseases (15-03-2008)“…The obligate intracellular bacterium Chlamydia trachomatis is the causative agent of sexually transmitted chlamydia infections. A panel of 116 recombinant C…”
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Analysis of the OspE Determinants Involved in Binding of Factor H and OspE-Targeting Antibodies Elicited during Borrelia burgdorferi Infection in Mice
Published in Infection and Immunity (01-06-2003)“…Classifications Services IAI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Identification of a linear epitope recognized by a monoclonal antibody directed to the heterogeneous nucleoriboprotein A2
Published in Protein and peptide letters (01-01-2014)“…Rheumatoid arthritis (RA) is a chronic autoimmune disorder, characterized by progressive joint destruction and disability. Classical autoantibodies of RA are…”
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Use of peptide antibodies to probe for the mitoxantrone resistance-associated protein MXR/BCRP/ABCP/ABCG2
Published in Biochimica et biophysica acta (20-09-2002)“…Recent studies have characterized the ABC half-transporter associated with mitoxantrone resistance in human cancer cell lines. Encoded by the ABCG2 gene,…”
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Peptide-Carrier Conjugation
Published in Methods in molecular biology (Clifton, N.J.) (2024)“…To produce antibodies against synthetic peptides, it is necessary to couple them to a protein carrier. This chapter provides a nonspecialist overview of…”
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