Search Results - "Hansen, Nils Jakob Vest"

PEARL-seq: A Photoaffinity Platform for the Analysis of Small Molecule-RNA Interactions by Mukherjee, Herschel, Blain, J. Craig, Vandivier, Lee E, Chin, Donovan N, Friedman, Jessica E, Liu, Fei, Maillet, Ashley, Fang, Chao, Kaplan, Jenifer B, Li, Jinxing, Chenoweth, David M, Christensen, Allan Beck, Petersen, Lars Kolster, Hansen, Nils Jakob Vest, Barrera, Luis, Kubica, Neil, Kumaravel, Gnanasambandam, Petter, Jennifer C

“…RNA is emerging as a valuable target for the development of novel therapeutic agents. The rational design of RNA-targeting small molecules, however, has been…”
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A Yoctoliter-Scale DNA Reactor for Small-Molecule Evolution by Hansen, Margit Haahr, Blakskjær, Peter, Petersen, Lars Kolster, Hansen, Tara Heitner, Højfeldt, Jonas Westergaard, Gothelf, Kurt Vesterager, Hansen, Nils Jakob Vest

“…The center of DNA three-way junctions, constituting a yoctoliter (10−24 L) volume, is applied as an efficient reactor to create DNA-encoded libraries of…”
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Allergen-specific polyclonal antibodies reduce allergic disease in a mouse model of allergic asthma by Moerch, Ulrik, Haahr Hansen, Margit, Vest Hansen, Nils Jakob, Rasmussen, Lone Kjaer, Oleksiewicz, Martin B, Frandsen, Torben P, Haurum, John S, Bregenholt, Søren

“…Recombinant allergen-specific immunoglobulin G (IgG) antibody therapy can reduce allergic asthma symptoms by inhibiting the immunoglobulin E (IgE)-mediated…”
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Fidelity by design: Yoctoreactor and binder trap enrichment for small-molecule DNA-encoded libraries and drug discovery by Blakskjaer, Peter, Heitner, Tara, Hansen, Nils Jakob Vest

“…•Efficient hit discovery process against challenging targets.•Discovery of potent hits to enzymes and protein–protein interaction targets.•Synthesis of…”
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Incomplete effector/memory differentiation of antigen‐primed CD8+ T cells in gene gun DNA‐vaccinated mice by Bartholdy, Christina, Stryhn, Anette, Hansen, Nils Jakob Vest, Buus, Søren, Thomsen, Allan Randrup

“…DNA vaccination is an efficient way to induce CD8+ T cell memory, but it is still unclear to what extent such memory responses afford protection in vivo. To…”
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Efficient assembly of recombinant major histocompatibility complex class I molecules with preformed disulfide bonds by Østergaard Pedersen, Lars, Nissen, Mogens Holst, Vest Hansen, Nils Jakob, Nielsen, Lise Lotte, Lauenmøller, Sanne Lise, Blicher, Thomas, Nansen, Anneline, Sylvester‐Hvid, Christina, Thromsen, Allan Randrup, Buus, Søren

“…The expression of major histocompatibility class I (MHC‐I) crucially depends upon the binding of appropriate peptides. MHC‐I from natural sources are therefore…”
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Phage display of peptide / major histocompatibility class I complexes by Vest Hansen, Nils Jakob, Østergaard Pedersen, Lars, Stryhn, Anette, Buus, Søren

“…Major histocompatibility complex class I (MHC‐I) molecules sample peptides from the intracellular environment and present them to cytotoxic T cells (CTL). To…”
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High-Throughput Polymerase Chain Reaction Cleanup in Microtiter Format by Vest Hansen, Nils Jakob, Pedersen, Lars Østergaard, Stryhn, Anette, Buus, Søren

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