Search Results - "Hansell, E J"

Patterns of protease production during prostate cancer progression: proteomic evidence for cascades in a transgenic model by Bok, R A, Hansell, E J, Nguyen, T P, Greenberg, N M, McKerrow, J H, Shuman, M A

“…Extracellular proteases are recognized as critical factors in the progression of a number of carcinomas, including prostate cancer. Matrix metalloproteases…”
Get full text

Expression and function of matrix metalloproteinases and their inhibitors at the maternal-embryonic boundary during mouse embryo implantation by Alexander, C M, Hansell, E J, Behrendtsen, O, Flannery, M L, Kishnani, N S, Hawkes, S P, Werb, Z

“…Gelatinase B, a matrix metalloproteinase (MMP) of high specific activity, is highly expressed and activated by mouse blastocysts in culture, and inhibition of…”
Get full text

Simian virus 40 transformation alters the actin cytoskeleton, expression of matrix metalloproteinases and inhibitors of metalloproteinases, and invasive behavior of normal and ataxia-telangiectasia human skin fibroblasts by Hansell, E J, Frisch, S M, Tremble, P, Murnane, J P, Werb, Z

“…Alterations in the actin cytoskeleton of normal cells result in changes in cell shape and adhesiveness and induce expression of matrix-degrading matrix…”
Get more information

T-Antigen inhibits metalloproteinase expression and invasion in human placental cells transformed with temperature-sensitive simian virus 40 by Logan, Susan K., Hansell, Elizabeth J., Damsky, Caroline H., Werb, Zena

“…Cellular transformation frequently induces invasive behavior in cells. The effects of simian virus (SV) 40 T-antigen on the relationship between…”
Get full text

Squamous cell carcinoma antigen 1 is an inhibitor of parasite-derived cysteine proteases by Kanaji, Sachiko, Tanaka, Yoko, Sakata, Yasuhisa, Takeshita, Kohei, Arima, Kazuhiko, Ohta, Shoichiro, Hansell, Elizabeth J., Caffrey, Conor, Mottram, Jeremy C., Lowther, Jonathan, Donnelly, Sheila, Stack, Colin, Kadowaki, Tomoko, Yamamoto, Kenji, McKerrow, James H., Dalton, John P., Coombs, Graham H., Izuhara, Kenji

“…The physiological significance of the squamous cell carcinoma antigens 1 (SCCA1) and SCCA2, members of the ovalbumin serpin family, remains unresolved. In this…”
Get full text

Discovery of potent thiosemicarbazone inhibitors of rhodesain and cruzain by Fujii, Naoaki, Mallari, Jeremy P., Hansell, Elizabeth J., Mackey, Z., Doyle, Patricia, Zhou, Y.M., Gut, Jiri, Rosenthal, Philip J., McKerrow, James H., Guy, R. Kiplin

“…Herein we report the synthesis and evaluation of a series of thiosemicarbazones as potential inhibitors of cysteine proteases relevant to parasitic diseases…”
Get full text