Search Results - "Hansell, Chris"

Universal expression and dual function of the atypical chemokine receptor D6 on innate-like B cells in mice by Hansell, Chris A.H., Schiering, Chris, Kinstrie, Ross, Ford, Laura, Bordon, Yvonne, McInnes, Iain B., Goodyear, Carl S., Nibbs, Robert J.B.

“…Mouse innate-like B cells are a heterogeneous collection of multifunctional cells that control infection, play housekeeping roles, contribute to adaptive…”
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Characterization of conventional and atypical receptors for the chemokine CCL2 on mouse leukocytes by Ford, Laura B, Cerovic, Vuk, Milling, Simon W F, Graham, Gerard J, Hansell, Chris A H, Nibbs, Robert J B

“…Chemokine-directed leukocyte migration is crucial for effective immune and inflammatory responses. Conventional chemokine receptors (cCKRs) directly control…”
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Atypical chemokine receptor ACKR2 mediates chemokine scavenging by primary human trophoblasts and can regulate fetal growth, placental structure, and neonatal mortality in mice by Teoh, Pek Joo, Menzies, Fiona M, Hansell, Chris A H, Clarke, Mairi, Waddell, Carolann, Burton, Graham J, Nelson, Scott M, Nibbs, Robert J B

“…Inflammatory chemokines produced in the placenta can direct the migration of placental leukocytes using chemokine receptors that decorate the surface of these…”
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The Atypical Chemokine Receptor D6 Contributes to the Development of Experimental Colitis by Bordon, Yvonne, Hansell, Chris A. H, Sester, David P, Clarke, Mairi, Mowat, Allan McI, Nibbs, Robert J. B

“…Proinflammatory CC chemokines control leukocyte recruitment and function during inflammation by engaging chemokine receptors expressed on circulating…”
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DARC and D6: silent partners in chemokine regulation? by Hansell, Chris A H, Hurson, Catherine E, Nibbs, Robert J B

“…Chemokine receptors adorn the surface of leukocytes and other cell types ready to translate the extracellular chemokine environment into functional cellular…”
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The atypical chemokine receptor ACKR2 suppresses Th17 responses to protein autoantigens by Hansell, Chris AH, MacLellan, Lindsay M, Oldham, Rachel S, Doonan, James, Chapple, Katie J, Anderson, Elinor JR, Linington, Christopher, McInnes, Iain B, Nibbs, Robert JB, Goodyear, Carl S

“…Chemokine‐directed leukocyte migration is a critical component of all innate and adaptive immune responses. The atypical chemokine receptor ACKR2 is expressed…”
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The odd couple: Innate-like B cells and the chemokine scavenger D6 by Hansell, Chris A.H., Nibbs, Robert J.B.

“…Comment on: Hansell CA, et al. Blood 2011; 117:5413-24…”
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Role of innate immune responses in the effectiveness of oncolytic adenovirus as an anticancer agent by Leung, Elaine Y, Dr, Weigert, Melanie, BSc, Walton, Josephine B, PhD, Ennis, Darren P, PhD, Athineos, Dimitris, PhD, Dowson, Suzanne, MSci, Hansell, Chris, PhD, Blyth, Karen, PhD, Graham, Gerard, PhD, McNeish, Iain A, PhD FRCP

“…Abstract Background Ovarian cancer is the deadliest gynaecological cancer, with fewer than half of patients surviving for more than 5 years. Oncolytic viruses…”
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Hemopoietic Cell Expression of the Chemokine Decoy Receptor D6 Is Dynamic and Regulated by GATA1 by McKimmie, Clive S, Fraser, Alasdair R, Hansell, Chris, Gutierrez, Laura, Philipsen, Sjaak, Connell, Laura, Rot, Antal, Kurowska-Stolarska, Mariola, Carreno, Paz, Pruenster, Monika, Chu, Chung-Ching, Lombardi, Giovanna, Halsey, Christina, McInnes, Iain B, Liew, Foo Y, Nibbs, Robert J, Graham, Gerard J

“…D6 scavenges inflammatory chemokines and is essential for the regulation of inflammatory and immune responses. Mechanisms explaining the cellular basis for D6…”
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Unique Features and Distribution of the Chicken CD83+ Cell by Hansell, Chris, Zhu, Xing Wu, Brooks, Heather, Sheppard, Mark, Withanage, Sam, Maskell, Duncan, McConnell, Ian

“…The central importance of dendritic cells (DC) in both innate and acquired immunity is well recognized in the mammalian immune system. By contrast DC have yet…”
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Using fluorescent chemokine uptake to detect chemokine receptors by fluorescent activated cell sorting by Ford, Laura B, Hansell, Chris A H, Nibbs, Robert J B

“…Fluorescent activated cell sorting (FACS) is a powerful technique that allows rapid quantitative cell-by-cell analysis of the expression of multiple distinct…”
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Enhanced CCR2 expression by ACKR2-deficient NK cells increases tumoricidal cell therapy efficacy by Hayes, Alan J, Pingen, Marieke, Wilson, Gillian, Hansell, Chris, Love, Samantha, Burgoyne, Paul, McElroy, Daniel, Bartolini, Robin, Vidler, Francesca, Schuette, Fabian, Gamble, Alistair, Campbell, Jordan, Galatis, Dimitrios, Campbell, John D M, Graham, Gerard J

“…Chemokines regulate leukocyte navigation to inflamed sites and specific tissue locales and may therefore be useful for ensuring accurate homing of cell…”
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Disease activity, burden and suffering in patients with ulcerative colitis in the UK cohort recruited into the global ICONIC study by Bhala, Neeraj, Hart, Ailsa, Watts, David, Lewis, Stephen, Ghosh, Subrata, Hansell, Chris, Ahmad, Tariq, Van Haaren, Stijn, Sensky, Tom

“…ObjectiveThe Understanding the Impact of Ulcerative Colitis and Its Associated Disease Burden on Patients (ICONIC) was a 2-year, global, prospective,…”
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Hemopoietic cell expression of the chemokine decoy receptor D6 is dynamic and regulated by GATA1 by McKimmie, Clive S, Fraser, Alasdair R, Hansell, Chris, Gutiérrez, Laura, Philipsen, Sjaak, Connell, Laura, Rot, Antal, Kurowska-Stolarska, Mariola, Carreno, Paz, Pruenster, Monika, Chu, Ching-Chung, Lombardi, Giovanna, Halsey, Christina, McInnes, Iain B, Liew, Foo Y, Nibbs, Robert J, Graham, Gerard J

“…D6 scavenges inflammatory chemokines and is essential for the regulation of inflammatory and immune responses. Mechanisms explaining the cellular basis for D6…”
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The atypical chemokine receptor D6 contributes to the development of experimental colitis1 by Bordon, Yvonne, Hansell, Chris A. H., Sester, David P, Clarke, Mairi, Mowat, Allan McI, Nibbs, Robert J. B.

“…Pro-inflammatory CC chemokines control leukocyte recruitment and function during inflammation by engaging chemokine receptors expressed on circulating…”
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Unique Features and Distribution of the Chicken CD83 super(+) Cell by Hansell, Chris, Zhu, Xing Wu, Brooks, Heather, Sheppard, Mark, Withanage, Sam, Maskell, Duncan, McConnell, Ian

“…The central importance of dendritic cells (DC) in both innate and acquired immunity is well recognized in the mammalian immune system. By contrast DC have yet…”
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Professional and part-time chemokine decoys in the resolution of inflammation by Hansell, Chris, Nibbs, Robert

“…Inflammation is essential for protection from infection and for the repair of damaged tissue. Much is now known about how inflammation is induced and…”
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