Search Results - "Hans-D. Flad"

The beta-thromboglobulins and platelet factor 4: blood platelet-derived CXC chemokines with divergent roles in early neutrophil regulation by Brandt, Ernst, Petersen, Frank, Ludwig, Andreas, Ehlert, Jan E., Bock, Lothar, Flad, Hans‐D.

“…The recruitment of neutrophil granulocytes to sites of tissue injury is one of the earliest events during host defense. Several chemotactic cytokines belonging…”
Get full text

The Cell Proliferation-Associated Antigen of Antibody Ki-67: A Very Large, Ubiquitous Nuclear Protein with Numerous Repeated Elements, Representing a New Kind of Cell Cycle-Maintaining Proteins by Schlüter, Carsten, Duchrow, Michael, Wohlenberg, Claudia, Michael H. G. Becker, Key, Göran, Hans-D. Flad, Gerdes, Johannes

“…The antigen defined by mAb Ki-67 is a human nuclear protein the expression of which is strictly associated with cell proliferation and which is widely used in…”
Get full text

An improved method for the species-specific assessment of mycobacteria in routinely formalin-fixed and paraffin-embedded tissues by Richter, E, Schlüter, C, Duchrow, M, Hahn, M, Rüsch-Gerdes, S, Galle, J, Flad, H D, Gerdes, J

“…A polymerase chain reaction (PCR) assay for the rapid and species-specific diagnosis of mycobacterial infections in paraffin-embedded clinical specimens was…”
Get more information

Actin: A Target of Lipopolysaccharid-Induced Phosphorylation in Human Monocytes by Hauschildt, Sunna, Schwarz, Claus, Heine, Holger, Ulmer, Artur J., Flad, Hans-D., Rietschel, Ernst T., Jensen, Ole N., Mann, Matthias

“…We have previously reported that lipopolysaccharide (LPS) causes altered phosphate labelling of cytosolic proteins of 36 kDa and 38 kDa (p36/38) and that…”
Get full text

Isolation of normal human follicular dendritic cells and CD4-independent in vitro infection by human immunodeficiency virus (HIV-1) by Stahmer, I, Zimmer, J P, Ernst, M, Fenner, T, Finnern, R, Schmitz, H, Flad, H D, Gerdes, J

“…Immunohistological and electron microscopy studies of lymph nodes from patients infected with the human immunodeficiency virus 1 (HIV-1) demonstrated that…”
Get more information

Tumor necrosis factor alpha and lymphotoxin production in Hodgkin's disease by Kretschmer, C, Jones, DB, Morrison, K, Schluter, C, Feist, W, Ulmer, AJ, Arnoldi, J, Matthes, J, Diamantstein, T, Flad, HD

“…It is likely that the characteristic histologic features of Hodgkin's disease reflect cytokine production by the tumor cell population. Tumor necrosis factor…”
Get full text

Detection of Mycobacterium leprae by three-primer PCR by Richter, E, Duchrow, M, Schlüter, C, Hahn, M, Flad, H D, Gerdes, J

“…Recently, polymerase chain reaction has been introduced for the species-specific assessment of Mycobacterium leprae (1). To avoid Southern blotting techniques…”
Get more information

Mycobacterium leprae DNA content, cellular and cytokine patterns in skin lesions of leprosy patients undergoing multidrug therapy (MDT) by Flad, H D, Richter, E, Schlüter, C, Duchrow, M, Arnoldi, J, Hahn, M, Graf von Ballestrem, W, Alvarenga, A E, Gerdes, J

“…Skin biopsies from untreated and MDT-treated patients were examined for infiltrating cells and cells producing the cytokines TNF-alpha, IFN-gamma, and IL-1…”
Get more information

Immunobiochemical and molecular biologic characterization of the cell proliferation-associated nuclear antigen that is defined by monoclonal antibody Ki-67 by Gerdes, J, Li, L, Schlueter, C, Duchrow, M, Wohlenberg, C, Gerlach, C, Stahmer, I, Kloth, S, Brandt, E, Flad, HD

“…The monoclonal antibody Ki-67 detects a human nuclear antigen that is present in proliferating cells, but absent in quiescent cells. The aim of this study was…”
Get full text

Biochemical characterization of a factor released by macrophages by Opitz, H G, Niethammer, D, Jackson, R C, Lemke, H, Huget, R, Flad, H D

Get more information

Humoral Primary Immune Response in Vitro in a Homologous Mouse System: Replacement of Fetal Calf Serum by a 2-Mercaptoethanol or Macrophage-Activated Fraction of Mouse Serum by Opitz, Hans G, Opitz, Uta, Lemke, Hilmar, Flad, Hans-D, Hewlett, Guy, Schlumberger, H. D

“…The primary immune response in mouse spleen cell cultures against heterologous red cell antigens is dependent on the medium being supplemented with selected…”
Get full text

Macrophages/Monocytes Require Cell-to-Cell Contact in Order to Regulate the Growth of a Murine Lymphoma Cell Line by Hewlett, Guy, Opitz, Hans-Georg, Flad, Hans D, Schlumberger, H. Dieter

“…The mechanism of the macrophage-regulated proliferation of the murine lymphoma cell line FIO 30 has been further investigated. It appears that the macrophage…”
Get full text

Assessment of mycobacterial DNA in cells and tissues of mycobacterial and sarcoid lesions by Richter, E, Greinert, U, Kirsten, D, Rüsch-Gerdes, S, Schlüter, C, Duchrow, M, Galle, J, Magnussen, H, Schlaak, M, Flad, H D, Gerdes, J

“…In this study we applied a polymerase chain reaction (PCR) assay for the detection and species-specific identification of mycobacteria to samples from patients…”
Get more information

Inhibition of 3H-thymidine incorporation of lymphocytes by a soluble factor from macrophages by Opitz, H G, Niethammer, D, Lemke, H, Flad, H D, Huget, R

Get more information

Nitric oxide synthase: mRNA expression of different isoforms in human monocytes/macrophages by Reiling, N, Ulmer, A J, Duchrow, M, Ernst, M, Flad, H D, Hauschildt, S

“…To detect mRNA expression of nitric oxide synthase (NOS) isoforms in human monocytes/macrophages reverse transcription polymerase chain reaction (RT-PCR) was…”
Get more information

Proliferation-associated Ki-67 protein is a target for autoantibodies in the human autoimmune disease systemic lupus erythematosus by Gerlach, C, Kubbutat, M, Schwab, U, Key, G, Flad, H D, Gerdes, J

Get more information

Induction of human interleukin 1 by bacterial and synthetic lipid A by Loppnow, H, Brade, L, Brade, H, Rietschel, E T, Kusumoto, S, Shiba, T, Flad, H D

“…Lipopolysaccharides (LPS) are well known inducers of interleukin 1 (IL 1). Here we show that synthetic heptaacyl Salmonella minnesota (compound 516) and…”
Get more information

The role of fetal calf serum in the primary immune response in vitro by Opitz, H G, Opitz, U, Lemke, H, Hewlett, G, Schreml, W, Flad, H D

“…The mode of action of 2-mercaptoethanol (2-ME) on the primary immune response in vitro was investigated. Fetal calf serum (FCS) was preincubated with 2-ME and…”
Get full text

Bithermic complement activation in cryoglobulinaemic serum by Rother, U, Rother, K, Flad, H D, Miescher, P A

Get more information

Disseminated mycobacterial histiocytosis due to M. Fortuitum associated with helper T-lymphocyte immune deficiency by Bültmann, B D, Flad, H D, Kaiserling, E, Müller-Hermelink, H K, Kratzsch, G, Galle, J, Schachenmayr, W, Heimpel, H, Wigger, H J, Haferkamp, O

“…Mycobacterial histiocytosis is a rare disease usually associated with haematological or immunological disorders. We report a fatal case caused by M. fortuitum…”
Get full text