Search Results - "Hans, Carl"

Perspectives on chronic inflammation in essential thrombocythemia, polycythemia vera, and myelofibrosis: is chronic inflammation a trigger and driver of clonal evolution and development of accelerated atherosclerosis and second cancer? by Hasselbalch, Hans Carl

“…The morbidity and mortality of patients with the chronic Philadelphia-negative myeloproliferative neoplasms (MPNs), essential thrombocythemia, polycythemia…”
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Time for revival of the red blood cell count and red cell mass in the differential diagnosis between essential thrombocythemia and polycythemia vera? by Hasselbalch, Hans Carl

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MPNs as Inflammatory Diseases: The Evidence, Consequences, and Perspectives by Hasselbalch, Hans Carl, Bjørn, Mads Emil

“…In recent years the evidence is increasing that chronic inflammation may be an important driving force for clonal evolution and disease progression in the…”
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The pathobiology of thrombosis, microvascular disease, and hemorrhage in the myeloproliferative neoplasms by Hasselbalch, Hans Carl, Elvers, Margitta, Schafer, Andrew I.

“…Thrombotic, vascular, and bleeding complications are the most common causes of morbidity and mortality in the Philadelphia chromosome–negative…”
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The platelet–cancer loop in myeloproliferative cancer. Is thrombocythemia an enhancer of cancer invasiveness and metastasis in essential thrombocythemia, polycythemia vera and myelofibrosis? by Hasselbalch, Hans Carl

“…Highlights • Platelets enhance cancer invasiveness and metastasis. • Elevated platelet counts are associated with inferior cancer survival. • Essential…”
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Chondromodulin 1 stabilizes the chondrocyte phenotype and inhibits endochondral ossification of porcine cartilage repair tissue by Klinger, Patricia, Surmann‐Schmitt, Cordula, Brem, Matthias, Swoboda, Bernd, Distler, Jörg H., Carl, Hans‐Dieter, von der Mark, Klaus, Hennig, Friedrich F., Gelse, Kolja

“…Objective To investigate the effect of chondromodulin 1 on the phenotype of osteochondral progenitor cells in cartilage repair tissue. Methods…”
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The Role of Reactive Oxygen Species in Myelofibrosis and Related Neoplasms by Bjørn, Mads Emil, Hasselbalch, Hans Carl

“…Reactive oxygen species (ROS) have been implicated in a wide variety of disorders ranging between traumatic, infectious, inflammatory, and malignant diseases…”
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Philadelphia-Negative Classical Myeloproliferative Neoplasms: Critical Concepts and Management Recommendations From European LeukemiaNet by BARBUI, Tiziano, BAROSI, Giovanni, KILADJIAN, Jean-Jacques, KRÖGER, Nicolaus, MESA, Ruben, MCMULLIN, Mary F, PARDANANI, Animesh, PASSAMONTI, Francesco, VANNUCCHI, Alessandro M, REITER, Andreas, SILVER, Richard T, VERSTOVSEK, Srdan, BIRGEGARD, Gunnar, TEFFERI, Ayalew, CERVANTES, Francisco, FINAZZI, Guido, GRIESSHAMMER, Martin, HARRISON, Claire, HASSELBALCH, Hans Carl, HEHLMANN, Rudiger, HOFFMAN, Ronald

“…We present a review of critical concepts and produce recommendations on the management of Philadelphia-negative classical myeloproliferative neoplasms,…”
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Chronic myeloproliferative neoplasms and subsequent cancer risk: a Danish population-based cohort study by Frederiksen, Henrik, Farkas, Dóra Körmendiné, Christiansen, Christian Fynbo, Hasselbalch, Hans Carl, Sørensen, Henrik Toft

“…Patients with chronic myeloproliferative neoplasms, including essential thrombocythemia (ET), polycythemia vera (PV), and chronic myeloid leukemia (CML), are…”
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Ruxolitinib and interferon-α2 combination therapy for patients with polycythemia vera or myelofibrosis: a phase II study by Sørensen, Anders Lindholm, Mikkelsen, Stine Ulrik, Knudsen, Trine Alma, Bjørn, Mads Emil, Andersen, Christen Lykkegaard, Bjerrum, Ole Weis, Brochmann, Nana, Patel, Dustin Andersen, Gjerdrum, Lise Mette Rahbek, El Fassi, Daniel, Kruse, Torben A, Larsen, Thomas Stauffer, Mourits-Andersen, Hans Torben, Nielsen, Claus Henrik, Ellervik, Christina, Pallisgaard, Niels, Thomassen, Mads, Kjær, Lasse, Skov, Vibe, Hasselbalch, Hans Carl

“…We report the final 2-year end-of-study results from the first clinical trial investigating combination treatment with ruxolitinib and low-dose pegylated…”
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Lower CXCR3 expression in both patients with neovascular AMD and advanced stages of chronic myeloproliferative blood cancers by Liisborg, Charlotte, Skov, Vibe, Kjær, Lasse, Hasselbalch, Hans Carl, Lykke Sørensen, Torben

“…Peripheral T cell CXCR3 expression has been found uniquely lower in patients having neovascular age-related macular degeneration (nAMD) than in healthy…”
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Serum levels of IL-4, IL-13 and IL-33 in patients with age-related macular degeneration and myeloproliferative neoplasms by Gotfredsen, Kathrine, Liisborg, Charlotte, Skov, Vibe, Kjær, Lasse, Hasselbalch, Hans Carl, Sørensen, Torben Lykke

“…Immune responses play a key role in the pathogenesis and progression of myeloproliferative neoplasms (MPN) and age-related macular degeneration (AMD). Recent…”
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Mathematical modelling as a proof of concept for MPNs as a human inflammation model for cancer development by Andersen, Morten, Sajid, Zamra, Pedersen, Rasmus K, Gudmand-Hoeyer, Johanne, Ellervik, Christina, Skov, Vibe, Kjær, Lasse, Pallisgaard, Niels, Kruse, Torben A, Thomassen, Mads, Troelsen, Jesper, Hasselbalch, Hans Carl, Ottesen, Johnny T

“…The chronic Philadelphia-negative myeloproliferative neoplasms (MPNs) are acquired stem cell neoplasms which ultimately may transform to acute myelogenous…”
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Elevated white blood cell counts in ischemic stroke patients are associated with increased mortality and new vascular events by Vo, Thao Phuong, Kristiansen, Marie Hvelplund, Hasselbalch, Hans Carl, Wienecke, Troels

“…Background and purposeHigh levels of white blood cells (WBC) in ischemic stroke have been shown to increase the risk of new vascular events and mortality in…”
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Second malignancies in hydroxyurea and interferon‐treated Philadelphia‐negative myeloproliferative neoplasms by Hansen, Iben Onsberg, Sørensen, Anders Lindholm, Hasselbalch, Hans Carl

“…Objective In an era of controversy in regard to ‘hydroxyurea‐leukaemogenicity’ and when interferon‐alfa2 (IFN) is being revived in the treatment of…”
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Response criteria for essential thrombocythemia and polycythemia vera: result of a European LeukemiaNet consensus conference by Barosi, Giovanni, Birgegard, Gunnar, Finazzi, Guido, Griesshammer, Martin, Harrison, Claire, Hasselbalch, Hans Carl, Kiladjian, Jean-Jacques, Lengfelder, Eva, McMullin, Mary Frances, Passamonti, Francesco, Reilly, John T., Vannucchi, Alessandro M., Barbui, Tiziano

“…European experts were convened to develop a definition of response to treatment in polycythemia vera (PV) and essential thrombocythemia (ET)…”
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CHIP-JAK2V617F, Chronic Inflammation, Abnormal Megakaryocyte Morphology, Organ Failure, and Multimorbidties by Kristiansen, Marie Hvelplund, Kjær, Lasse, Skov, Vibe, Larsen, Morten Kranker, Ellervik, Christina, Hasselbalch, Hans Carl Carl, Wienecke, Troels

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Whole blood transcriptional profiling reveals deregulation of oxidative and antioxidative defence genes in myelofibrosis and related neoplasms. Potential implications of downregulation of Nrf2 for genomic instability and disease progression by Hasselbalch, Hans Carl, Thomassen, Mads, Riley, Caroline Hasselbalch, Kjær, Lasse, Larsen, Thomas Stauffer, Jensen, Morten K, Bjerrum, Ole Weis, Kruse, Torben A, Skov, Vibe

“…The Philadelphia-negative chronic myeloproliferative neoplasms - essential thrombocythemia (ET), polycythemia vera (PV), and myelofibrosis (MF) (MPNs) - have…”
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Soccer Boots Elevate Plantar Pressures in Elite Male Soccer Professionals by Carl, Hans-Dieter, Pauser, Johannes, Swoboda, Bernd, Jendrissek, Andreas, Brem, Matthias

“…OBJECTIVE:The present study measured the difference in peak plantar pressure between running shoes and soccer shoes in male soccer professionals [mean (SD)age,…”
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Smoking and Increased White and Red Blood Cells by Pedersen, Kasper Mønsted, Çolak, Yunus, Ellervik, Christina, Hasselbalch, Hans Carl, Bojesen, Stig Egil, Nordestgaard, Børge Grønne

“…Objective- Whether tobacco smoking causally affects white and red blood cells and thrombocyte counts is unknown. Using a Mendelian randomization approach, we…”
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