Search Results - "Hanrahan, James P."

Direct evidence on the contribution of a missense mutation in GDF9 to variation in ovulation rate of Finnsheep by Mullen, Michael P, Hanrahan, James P

“…The Finnish Landrace (Finnsheep) is a well known high-prolificacy sheep breed and has been used in many countries as a source of genetic material to increase…”
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Mutations in the Genes for Oocyte-Derived Growth Factors GDF9 and BMP15 Are Associated with Both Increased Ovulation Rate and Sterility in Cambridge and Belclare Sheep (Ovis aries) by HANRAHAN, James P, GREGAN, Scott M, MULSANT, Philippe, MULLEN, Michael, DAVIS, George H, POWELL, Richard, GALLOWAY, Susan M

“…Belclare and Cambridge are prolific sheep breeds, the origins of which involved selecting ewes with exceptionally high litter size records from commercial…”
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Effects of Age at First Joining and Ewe Genotype on the Performance of Two-Tooth Ewes and That of Their Progeny to Slaughter by Keady, Timothy W J, Hanrahan, James P

“…The effects of first-joining age (7 or 19 months) and genotype on ewe performance when joined to lamb at 2 years, and the performance of their progeny, were…”
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Variation in the Ovine Abomasal Lymph Node Transcriptome between Breeds Known to Differ in Resistance to the Gastrointestinal Nematode by Ahmed, Albin M, Good, Barbara, Hanrahan, James P, McGettigan, Paul, Browne, John, Keane, Orla M, Bahar, Bojlul, Mehta, Jai, Markey, Bryan, Lohan, Amanda, Sweeney, Torres

“…Texel lambs are known to be more resistant to gastrointestinal nematode (GIN) infection than Suffolk lambs, with a greater ability to limit infection. The…”
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A Population Genomics Analysis of the Native Irish Galway Sheep Breed by McHugo, Gillian P., Browett, Sam, Randhawa, Imtiaz A. S., Howard, Dawn J., Mullen, Michael P., Richardson, Ian W., Park, Stephen D. E., Magee, David A., Scraggs, Erik, Dover, Michael J., Correia, Carolina N., Hanrahan, James P., MacHugh, David E.

“…The Galway sheep population is the only native Irish sheep breed and this livestock genetic resource is currently categorised as ‘at-risk’. In the present…”
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differential interplay between the expression of Th1/Th2/Treg related cytokine genes in Teladorsagia circumcincta infected DRB11101 carrier lambs by Hassan, Musa, Hanrahan, James P, Good, Barbara, Mulcahy, Grace, Sweeney, Torres

“…Substantial debate exists on whether the immune response between sheep resistant and susceptible to gastrointestinal nematodes can be differentiated into a Th1…”
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dynamic influence of the DRB11101 allele on the resistance of sheep to experimental Teladorsagia circumcincta infection by Hassan, Musa, Good, Barbara, Hanrahan, James P, Campion, Deirdre, Sayers, Gearoid, Mulcahy, Grace, Sweeney, Torres

“…Suffolk sheep carrying the DRB1*1101 (previously referred to as- DRB1*0203 or G2) allele have been reported to show increased resistance to natural…”
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Gastrointestinal nematode control practices on lowland sheep farms in Ireland with reference to selection for anthelmintic resistance by Patten, Thomas, Good, Barbara, Hanrahan, James P, Mulcahy, Grace, de Waal, Theo

“…Gastrointestinal parasitism is a widely recognised problem in sheep production, particularly for lambs. While anthelmintics have a pivotal role in controlling…”
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Risk factors for, and genetic association with, intestinal atresia in dairy calves by Keane, Orla M., Carthy, Tara R., Hanrahan, James P., Matthews, Daragh, McEwan, John C., Rowe, Suzanne J., Kenneally, Jonathon, Mee, John F.

“…Intestinal atresia is an under‐diagnosed congenital defect in cattle. It results in complete occlusion of the intestinal lumen and, unless surgically…”
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Live weight as a basis for targeted selective treatment of lambs post-weaning by Keegan, Jason D., Good, Barbara, Hanrahan, James P., Lynch, Ciaran, de Waal, Theo, Keane, Orla M.

“…•Targeted selective anthelmintic treatment was carried out with selection based on lamb live weight.•Withholding anthelmintic treatment from lambs had a…”
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Investigation of Prolific Sheep from UK and Ireland for Evidence on Origin of the Mutations in BMP15 (FecXG, FecXB) and GDF9 (FecGH) in Belclare and Cambridge Sheep by Mullen, Michael P., Hanrahan, James P., Howard, Dawn J., Powell, Richard

“…This paper concerns the likely origin of three mutations with large effects on ovulation rate identified in the Belclare and Cambridge sheep breeds; two in the…”
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Response to Teladorsagia circumcincta infection in Scottish Blackface lambs with divergent phenotypes for nematode resistance by McRae, Kathryn M., Good, Barbara, Hanrahan, James P., Glynn, Assumpta, O’Connell, Mary J., Keane, Orla M.

“…•We developed a model to reliably identify nematode resistant and susceptible lambs.•We found that resistant lambs had significantly lower faecal egg count.•We…”
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Transcriptional profiling of the ovine abomasal lymph node reveals a role for timing of the immune response in gastrointestinal nematode resistance by McRae, Kathryn M., Good, Barbara, Hanrahan, James P., McCabe, Matthew S., Cormican, Paul, Sweeney, Torres, O’Connell, Mary J., Keane, Orla M.

“…•Nematode resistant and susceptible lambs were identified using a previously developed model.•Resistant lambs had more immature and shorter worms.•Inflammation…”
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Can the amount of digestible undegraded protein offered to ewes during late pregnancy affect the performance and immune response of their offspring to gastrointestinal nematodes? by Sebastiano, Rocco S., Sweeney, Torres, Good, Barbara, Hanrahan, James P., Keady, Timothy W.J.

“…•Two concentrates, differing in digestible undegraded protein (DUP), were formulated.•DUP intake in late pregnancy varied from 26 to 72g/d.•MP supply as a…”
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Can the amount of digestible undegraded protein offered to ewes in late pregnancy affect the periparturient change in resistance to gastrointestinal nematodes? by Sebastiano, Rocco S., Sweeney, Torres, Keady, Timothy W.J., Hanrahan, James P., Good, Barbara

“…•Two concentrates, differing in digestible undegraded protein (DUP), were formulated.•Concentrate were offered to housed ewes during late pregnancy.•DUP intake…”
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A nationwide survey of anthelmintic treatment failure on sheep farms in Ireland by Keegan, Jason D, Keane, Orla M, Good, Barbara, De Waal, Theo, Denny, Marian, Hanrahan, James P, Fitzgerald, William, Sheehan, Maresa

“…Between 2013 and 2015 the Department of Agriculture, Food and the Marine (DAFM) administered a sheep technology adoption programme (STAP), with the aim of…”
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DNA Tests in Prolific Sheep from Eight Countries Provide New Evidence on Origin of the Booroola (FecB) Mutation by DAVIS, George H, GALLOWAY, Susan M, INOUNU, Ismeth, TIESNAMURTI, Bess, MARTYNIUK, Elzbieta, EYTHORSDOTTIR, Emma, MULSANT, Philippe, LECERF, Frederic, HANRAHAN, James P, BRADFORD, G. Eric, WILSON, Theresa, ROSS, Ian K, GREGAN, Scott M, WARD, Jamie, NIMBKAR, Bon V, GHALSASI, Pradip M, NIMBKAR, Chanda, GRAY, G. Douglas, SUBANDRIYO

“…Recent discoveries that high prolificacy in sheep carrying the Booroola gene ( FecB ) is the result of a mutation in the BMPIB receptor and high prolificacy in…”
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Effect of site of deposition on the fertility of sheep inseminated with frozen-thawed semen by Richardson, Lorraine, Hanrahan, James P., Donovan, Anne, Martí, Jose I., Fair, Sean, Evans, Alex C.O., Lonergan, Pat

“…The widespread use of artificial insemination (AI) in sheep is currently prevented due to the lack of a cost effective insemination technique utilising…”
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Physiological effects of major genes affecting ovulation rate in sheep by MCNATTY, Kenneth P, GALLOWAY, Susan M, JUENGEL, Jenny L, WILSON, Theresa, SMITH, Peter, HUDSON, Norma L, O'CONNELL, Anne, BIBBY, Adrian H, HEATH, Derek A, DAVIS, George H, HANRAHAN, James P

“…Genetic mutations with major effects on ovulation rate in sheep were recently identified in two genes of the transforming growth factor (TGFbeta) superfamily…”
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Investigation of prolific sheep from UK and Ireland for evidence on origin of the mutations in BMP15 (FecX(G), FecX(B)) and GDF9 (FecG(H)) in Belclare and Cambridge sheep by Mullen, Michael P, Hanrahan, James P, Howard, Dawn J, Powell, Richard

“…This paper concerns the likely origin of three mutations with large effects on ovulation rate identified in the Belclare and Cambridge sheep breeds; two in the…”
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