Search Results - "Hannuniemi, R."

Characteristics of clodronate-induced apoptosis in osteoclasts and macrophages by Selander, K S, Mönkkönen, J, Karhukorpi, E K, Härkönen, P, Hannuniemi, R, Väänänen, H K

“…Bisphosphonates (BPs), such as clodronate and pamidronate, are inhibitors of bone resorption and are used on a widespread basis in the treatment of…”
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Long-term administration of clodronate does not prevent fracture healing in rats by Koivukangas, A, Tuukkanen, J, Kippo, K, Jämsä, T, Hannuniemi, R, Pasanen, I, Väänänen, K, Jalovaara, P

“…Clinicians have been concerned that fractures do not heal properly in individuals exposed to bisphosphonate treatment, a treatment that strongly affects bone…”
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Effects of long-term administration of clodronate on growing rat bone by Koivukangas, A, Tuukkanen, J, Hannuniemi, R, Jämsa, T, Kippo, K, Jalovaara, P

“…Bisphosphonates inhibit bone resorption. Short-term bisphosphonate treatment at therapeutical dosage has been shown to be safe, but there are only a few…”
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Comparison of radiographic and pQCT analyses of healing rat tibial fractures by Jämsä, T, Koivukangas, A, Kippo, K, Hannuniemi, R, Jalovaara, P, Tuukkanen, J

“…Fracture healing and callus formation have traditionally been evaluated by using X-ray radiography. Here we compared X-ray radiography and peripheral…”
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Long-term effects of clodronate on growing rat bone by Lepola, V.T., Hannuniemi, R., Kippo, K., Laurén, L., Jalovaara, P., Väänänen, H.K.

“…For evaluating the long-term effects of the bisphosphonate compound clodronate on the rat skeleton, 100 female rats were given subcutaneous injections of…”
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Effect of clodronate on established adjuvant arthritis by ÖSTERMAN, T, KIPPO, K, LAUREN, L, HANNUNIEMI, R, SELLMAN, R

“…The rat adjuvant arthritis model was used to study the effect of disodium clodronate on inflammation and destruction of tarsal bones and joints. Male Lewis…”
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A comparison of clodronate and indomethacin in the treatment of adjuvant arthritis by Osterman, T, Kippo, K, Laurén, L, Pasanen, I, Hannuniemi, R, Sellman, R

“…The therapeutic effects of an anti-resorptive agent, clodronate, were compared with the effects of an anti-inflammatory agent, indomethacin, in rat adjuvant…”
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Effect of clodronate on established collagen-induced arthritis in rats by Osterman, T, Kippo, K, Laurén, L, Hannuniemi, R, Sellman, R

“…The collagen-induced arthritis model in rats was used to study the effect of disodium clodronate on inflammation and destruction of tarsal, metatarsal, and…”
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Slow-release clodronate in prevention of inflammation and bone loss associated with adjuvant arthritis by Osterman, T, Virtamo, T, Laurén, L, Kippo, K, Pasanen, I, Hannuniemi, R, Väänänen, K, Sellman, R

“…The effects of slow-release calcium clodronate on rat adjuvant arthritis were investigated using two different dosing schedules. In prophylactic treatment,…”
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The effect of orally administered clodronate on bone mineral density and bone geometry in ovariectomized rats by Osterman, T, Laurén, L, Kuurtamo, P, Hannuniemi, R, Isaksson, P, Kippo, K, Peng, Z, Väänänen, H K, Sellman, R

“…The effects of clodronate administered p.o. on bone mineral density (BMD), bone geometry and strength of bone were investigated in 6-month-old ovariectomized…”
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Distribution of clodronate in the bone of adult rats and its effects on trabecular and cortical bone by Osterman, T, Virtamo, T, Kippo, K, Laurén, L, Pasanen, I, Hannuniemi, R, Sellman, R

“…Distribution of clodronate in cancellous and cortical bone of the femur and in cancellous bone of lumbar vertebrae in adult rats was examined by means of…”
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Effect of clodronate treatment on established bone loss in ovariectomized rats by Kippo, K, Hannuniemi, R, Laurén, L, Peng, Z, Kuurtamo, P, Virtamo, T, Isaksson, P, Österman, T, Väänänen, H.K, Sellman, R

“…The ability of clodronate to prevent bone loss and weakening of bone strength was studied in adult rats with established osteopenia. Six-month-old female…”
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The effects of clodronate on increased bone turnover and bone loss due to ovariectomy in rats by KIPPO, K, HANNUNIEMI, R, VIRTAMO, T, LAUREN, L, IKÄVALKO, H, KOVANEN, V, ÖSTERMAN, T, SELLMAN, R

“…The present study was carried out to investigate the ability of clodronate to inhibit ovariectomy-induced bone loss and increased bone turnover in rats…”
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Clodronate prevents bone loss in aged ovariectomized rats by Kippo, K, Hannuniemi, R, Laurén, L, Peng, Z, Isaksson, P, Virtamo, T, Osterman, T, Pasanen, I, Sellman, R, Väänänen, H K

“…The purpose of this study was to investigate the ability of clodronate to prevent ovariectomy (OVX)-induced osteopenia in aged rats. Fourteen-month-old female…”
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L-carnitine uptake by mouse brain synaptosomal preparations: competitive inhibition by GABA by HANNUNIEMI, R, KONTRO, P

“…The uptake of L-carnitine was characterized in mouse brain synaptosomal preparations, with an emphasis on mutual interactions with GABA uptake systems. The…”
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Comparative molecular field analysis of some clodronic acid esters by Bjorkroth, J. P, Pakkanen, T. A, Lindroos, J, Pohjala, E, Hanhijarvi, H, Lauren, L, Hannuniemi, R, Juhakoski, A, Kippo, K, Kleimola, T

“…Comparative molecular field analysis (CoMFA) has been used as a three-dimensional quantitative structure-activity relationship (QSAR) method to correlate three…”
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Uptake of leucine, lysine, aspartic acid, and glycine into isolated neurons and astrocytes by Hannuniemi, R, Oja, S S

“…The uptake of tritium-labeled L-leucine, L-lysine, L-aspartic acid, and glycine by neurons and astrocytes isolated from the cerebral cortex of 3-week-old rats…”
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Stimulation of amino acid accumulation in neuroblastoma and astrocytoma cells by L-histidine by HANNUNIEMI, R, HOLOPAINEN, I, KORPI, E. R, OJA, S. S

“…Uptake of amino acids by cultured neuroblastoma and astrocytoma cells was studied in the presence and absence of L-histidine. Intracellularly accumulated…”
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Evaluating the density of fracture callus from radiographs and by quantitative CT by Jamsa, T., Koivukangas, A., Kippo, K., Hannuniemi, R., Jalovaara, P., Tuukkanen, J.

“…Fracture healing and callus formation have traditionally been evaluated by using X-ray radiography. Here we compared X-ray radiography and peripheral…”
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Absence of mutagenic activity of ticlopidine in the Ames Salmonella/microsome test by Hannuniemi, R, Sellman, R

“…Ticlopidine hydrochloride, 5-(o-chlorobenzyl)-4,5,6,7-tetrahydrothieno[3,2-c]pyridine hydrochloride, a platelet aggregation inhibitor, was tested for mutagenic…”
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