Search Results - "Hannukainen, J. C"

Elevated Glucose Oxidation, Reduced Insulin Secretion, and a Fatty Heart May Be Protective Adaptions in Ischemic CAD by Hannukainen, J. C, Lautamäki, R, Mari, A, Pärkkä, J. P, Bucci, M, Guzzardi, M. A, Kajander, S, Tuokkola, T, Knuuti, J, Iozzo, P

“…Background: Insulin resistance, β-cell dysfunction, and ectopic fat deposition have been implicated in the pathogenesis of coronary artery disease (CAD) and…”
Get full text

Validation of [18F]fluorodeoxyglucose and positron emission tomography (PET) for the measurement of intestinal metabolism in pigs, and evidence of intestinal insulin resistance in patients with morbid obesity by Honka, H., Mäkinen, J., Hannukainen, J. C., Tarkia, M., Oikonen, V., Teräs, M., Fagerholm, V., Ishizu, T., Saraste, A., Stark, C., Vähäsilta, T., Salminen, P., Kirjavainen, A., Soinio, M., Gastaldelli, A., Knuuti, J., Iozzo, P., Nuutila, P.

“…Aims/hypothesis The role of the intestine in the pathogenesis of metabolic diseases is gaining much attention. We therefore sought to validate, using an animal…”
Get full text

Exercise training alters lipoprotein particles independent of brown adipose tissue metabolic activity by Motiani, P., Teuho, J., Saari, T., Virtanen, K. A., Honkala, S. M., Middelbeek, R. J., Goodyear, L. J., Eskola, O., Andersson, J., Löyttyniemi, E., Hannukainen, J. C., Nuutila, P.

“…Summary Introduction New strategies for weight loss and weight maintenance in humans are needed. Human brown adipose tissue (BAT) can stimulate energy…”
Get full text

The effect of 12‐month enzyme replacement therapy on myocardial perfusion in patients with Fabry disease by Kalliokoski, R. J., Kantola, I., Kalliokoski, K. K., Engblom, E., Sundell, J., Hannukainen, J. C., Janatuinen, T., Raitakari, O. T., Knuuti, J., Penttinen, M., Viikari, J., Nuutila, P.

“…Summary Fabry disease (McKusick 301500) is an X‐linked lysosomal storage disorder secondary to deficient α‐galactosidase A activity which leads to the…”
Get full text

Increased insulin‐stimulated glucose uptake in both leg and arm muscles after sprint interval and moderate‐intensity training in subjects with type 2 diabetes or prediabetes by Sjöros, T. J., Heiskanen, M. A., Motiani, K. K., Löyttyniemi, E., Eskelinen, J‐J., Virtanen, K. A., Savisto, N. J., Solin, O., Hannukainen, J. C., Kalliokoski, K. K.

“…We investigated the effects of sprint interval training (SIT) and moderate‐intensity continuous training (MICT) on glucose uptake (GU) during hyperinsulinemic…”
Get full text

Autonomic Function Predicts Fitness Response to Short-Term High-Intensity Interval Training by Kiviniemi, A M, Tulppo, M P, Eskelinen, J J, Savolainen, A M, Kapanen, J, Heinonen, I H A, Hautala, A J, Hannukainen, J C, Kalliokoski, K K

“…We tested the hypothesis that baseline cardiac autonomic function and its acute response to all-out interval exercise explains individual fitness responses to…”
Get more information

Imaging of Organ Metabolism in Obesity and Diabetes: Treatment Perspectives by Hannukainen, J C, Guzzardi, M A, Virtanen, K A, Sanguinetti, E, Nuutila, P, Iozzo, P

“…Obesity and diabetes are growing threats for cardiovascular diseases (CVD) and heart failure. In order to identify early and effective treatment or prevention…”
Get more information

Myocardial and peripheral vascular functional adaptation to exercise training by Hannukainen, J. C., Janatuinen, T., Toikka, J. O., Järvisalo, M. J., Heinonen, O. J., Kapanen, J., Någren, K., Nuutila, P., Kujala, U. M., Kaprio, J., Knuuti, J., Kalliokoski, K. K.

“…Exercise training seems to restore impaired vascular function in both peripheral and myocardial vessels in patients with coronary artery and peripheral…”
Get full text

Human Bone Marrow Adipose Tissue is a Metabolically Active and Insulin-Sensitive Distinct Fat Depot by Pham, Tam T, Ivaska, Kaisa K, Hannukainen, Jarna C, Virtanen, Kirsi A, Lidell, Martin E, Enerbäck, Sven, Mäkelä, Keijo, Parkkola, Riitta, Piirola, Sauli, Oikonen, Vesa, Nuutila, Pirjo, Kiviranta, Riku

“…Abstract Context Bone marrow (BM) in adult long bones is rich in adipose tissue, but the functions of BM adipocytes are largely unknown. We set out to…”
Get full text

Hyperthyroidism Increases Brown Fat Metabolism in Humans by Lahesmaa, Minna, Orava, Janne, Schalin-Jäntti, Camilla, Soinio, Minna, Hannukainen, Jarna C, Noponen, Tommi, Kirjavainen, Anna, Iida, Hidehiro, Kudomi, Nobuyuki, Enerbäck, Sven, Virtanen, Kirsi A, Nuutila, Pirjo

“…Context: Thyroid hormones are important regulators of brown adipose tissue (BAT) development and function. In rodents, BAT metabolism is up-regulated by…”
Get full text

Mildly elevated liver fat content is characterised by central insulin resistance: evidence from a positron emission tomography study by Honka, MJ, Tuomola, N, Bucci, M, Immonen, H, Saunavaara, V, Laine, S, Sjoros, T, Garthwaite, T, Virtanen, KA, Hannukainen, JC, Kalliokoski, KK, Heinonen, IHA, Rebelos, E, Nuutila, P

Get full text

The Obesity Risk SNP (rs17782313) near the MC4R Gene Is Not Associated with Brain Glucose Uptake during Insulin Clamp-A Study in Finns by Rebelos, Eleni, Honka, Miikka-Juhani, Ekblad, Laura, Bucci, Marco, Hannukainen, Jarna C, Fernandes Silva, Lilian, Virtanen, Kirsi A, Nummenmaa, Lauri, Nuutila, Pirjo

“…The melanocortin system is involved in the control of adiposity through modulation of food intake and energy expenditure. The single nucleotide polymorphism…”
Get full text

Exercise training improves insulin sensitivity in abdominal adipose tissue but not in brown adipose tissue in healthy, sedentary, middle aged men by Motiani, KK, Savolainen, A, Eskelinen, JJ, Virtanen, KA, Bostrom, P, Jensen, J, Parkkola, R, Saunavaara, V, Knuuti, J, Nuutila, P, Kalliokoski, KK, Hannukainen, JC

Get full text

Cardiac structure and function in monozygotic twin pairs discordant for physical fitness by Hannukainen, Jarna C, Kujala, Urho M, Toikka, Jyri, Heinonen, Olli J, Kapanen, Jukka, Vahlberg, Tero, Kaprio, Jaakko, Kalliokoski, Kari K

“…1 Turku PET Centre, 2 Paavo Nurmi Centre, Department of Physiology, and 3 Department of Biostatics, University of Turku, Turku, Finland; 4 Department of Health…”
Get full text