Search Results - "Hanners, Natasha W."
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Western Zika Virus in Human Fetal Neural Progenitors Persists Long Term with Partial Cytopathic and Limited Immunogenic Effects
Published in Cell reports (Cambridge) (14-06-2016)“…The recent Zika virus (ZIKV) outbreak in the Western hemisphere is associated with severe pathology in newborns, including microcephaly and brain damage. The…”
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LY6E impairs coronavirus fusion and confers immune control of viral disease
Published in Nature microbiology (01-11-2020)“…Zoonotic coronaviruses (CoVs) are substantial threats to global health, as exemplified by the emergence of two severe acute respiratory syndrome CoVs (SARS-CoV…”
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Challenges and advances in the medical treatment of granulomatous amebic encephalitis
Published in Therapeutic advances in infectious disease (01-01-2024)“…Granulomatous amebic encephalitis, caused by the free-living amebae Balamuthia mandrillaris or Acanthamoeba species, is a rare and deadly infectious syndrome…”
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LY6E is a pan-coronavirus restriction factor in the respiratory tract
Published in Nature microbiology (01-08-2023)“…LY6E is an antiviral restriction factor that inhibits coronavirus spike-mediated fusion, but the cell types in vivo that require LY6E for protection from…”
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A NIK–SIX signalling axis controls inflammation by targeted silencing of non-canonical NF-κB
Published in Nature (London) (11-04-2019)“…The non-canonical NF-κB signalling cascade is essential for lymphoid organogenesis, B cell maturation, osteoclast differentiation, and inflammation in mammals…”
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Shiftless inhibits flavivirus replication in vitro and is neuroprotective in a mouse model of Zika virus pathogenesis
Published in Proceedings of the National Academy of Sciences - PNAS (07-12-2021)“…Flaviviruses such as Zika virus and West Nile virus have the potential to cause severe neuropathology if they invade the central nervous system. The type I…”
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SARS-CoV-2 infection associated with hepatitis in an infant with X-linked severe combined immunodeficiency
Published in Clinical immunology (Orlando, Fla.) (01-03-2021)“…X-linked severe combined immunodeficiency (X-SCID) is a disorder of adaptive immunity caused by mutations in the IL-2 receptor common gamma chain gene…”
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A NIK-SIX signalling axis controls inflammation by targeted silencing of non-canonical NF-[kappa]B
Published in Nature (London) (01-04-2019)“…The non-canonical NF-[kappa]B signalling cascade is essential for lymphoid organogenesis, B cell maturation, osteoclast differentiation, and inflammation in…”
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A NIK-SIX signaling axis controls inflammation by targeted silencing of noncanonical NF-κB
Published in Nature (London) (20-03-2019)“…The non-canonical NF-κB signaling cascade is essential for lymphoid organogenesis, B-cell maturation, osteoclast differentiation, and inflammation in mammals 1…”
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