Search Results - "Hannawacker, Annette"

Optical Mapping of cAMP Signaling at the Nanometer Scale by Bock, Andreas, Annibale, Paolo, Konrad, Charlotte, Hannawacker, Annette, Anton, Selma E., Maiellaro, Isabella, Zabel, Ulrike, Sivaramakrishnan, Sivaraj, Falcke, Martin, Lohse, Martin J.

“…Cells relay a plethora of extracellular signals to specific cellular responses by using only a few second messengers, such as cAMP. To explain signaling…”
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Experimental and mathematical analysis of cAMP nanodomains by Lohse, Christian, Bock, Andreas, Maiellaro, Isabella, Hannawacker, Annette, Schad, Lothar R, Lohse, Martin J, Bauer, Wolfgang R

“…In their role as second messengers, cyclic nucleotides such as cAMP have a variety of intracellular effects. These complex tasks demand a highly organized…”
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Novel Single Chain cAMP Sensors for Receptor-induced Signal Propagation by Nikolaev, Viacheslav O., Bünemann, Moritz, Hein, Lutz, Hannawacker, Annette, Lohse, Martin J.

“…cAMP is a universal second messenger of many G-protein-coupled receptors and regulates a wide variety of cellular events. cAMP exerts its effects via…”
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Fluorescence Resonance Energy Transfer–Based Analysis of cAMP Dynamics in Live Neonatal Rat Cardiac Myocytes Reveals Distinct Functions of Compartmentalized Phosphodiesterases by Mongillo, Marco, McSorley, Theresa, Evellin, Sandrine, Sood, Arvind, Lissandron, Valentina, Terrin, Anna, Huston, Elaine, Hannawacker, Annette, Lohse, Martin J, Pozzan, Tullio, Houslay, Miles D, Zaccolo, Manuela

“…Cardiac myocytes have provided a key paradigm for the concept of the compartmentalized cAMP generation sensed by AKAP-anchored PKA. Phosphodiesterases (PDEs)…”
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Optical Mapping of cAMP Signaling at the Nanometer Scale by Bock, Andreas, Annibale, Paolo, Konrad, Charlotte, Hannawacker, Annette, Anton, Selma E., Maiellaro, Isabella, Zabel, Ulrike, Sivaramakrishnan, Sivaraj, Falcke, Martin, Lohse, Martin J.

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PKA catalytic subunit mutations in adrenocortical Cushing’s adenoma impair association with the regulatory subunit by Calebiro, Davide, Hannawacker, Annette, Lyga, Sandra, Bathon, Kerstin, Zabel, Ulrike, Ronchi, Cristina, Beuschlein, Felix, Reincke, Martin, Lorenz, Kristina, Allolio, Bruno, Kisker, Caroline, Fassnacht, Martin, Lohse, Martin J.

“…We recently identified a high prevalence of mutations affecting the catalytic (Cα) subunit of protein kinase A (PKA) in cortisol-secreting adrenocortical…”
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Mutation of Asn293 to Asp in transmembrane helix VI abolishes agonist-induced but not constitutive activity of the beta(2)-adrenergic receptor by Hannawacker, Annette, Krasel, Cornelius, Lohse, Martin J

“…The beta(2)-adrenergic receptor has been shown to display significant constitutive activity (i.e., in the absence of agonist) in addition to agonist-induced…”
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