Search Results - "Hanna, Reda G"
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N-Amination of Indoles on Pilot-Plant Scale via Simultaneous and Proportional Metering of Reagents
Published in Organic process research & development (20-05-2011)“…The N-amination of indoles on large scale, utilizing a portable Coriolis mass flow metering and pumping system that provides precise dispensing of two reagent…”
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Chemical Development of the Casein Kinase I - Epsilon Inhibitor: 3-(3-Fluorophenyl)sulfanyl-1H-pyrrolo[3,2-b]pyridine-2-carboxylic Acid Amide
Published in Organic process research & development (16-09-2011)“…The development of a scalable process for 3-arylsulfanyl-1H-pyrrolo[3,2-b]pyridine-2-carboxylic acid amides (1), potent casein kinase I inhibitors, is…”
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(Imidazolylphenyl)pyrrol-2-one inhibitors of cardiac cAMP phosphodiesterase
Published in Journal of medicinal chemistry (16-04-1993)“…Seven 3-alkyl-4-aryl-1,5-dihydro-2H-pyrrol-2-ones were prepared as potential inhibitors of cardiac cAMP phosphodiesterase (PDE). The design of these compounds…”
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Cardiotonic agents. 6. Histamine analogs as potential cardiovascular selective H2 agonists
Published in Journal of medicinal chemistry (01-06-1990)“…Twenty-six alkyl and aralkyl histamine analogues were prepared as potential cardiotonic agents. Compounds were designed to allow interaction with a putative…”
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Heterocyclic analogs of benzamide antiarrhythmic agents
Published in Journal of medicinal chemistry (01-03-1989)“…A series of heterocyclic N-[(diethylamino)alkyl]arenamides related to acecainide was prepared and examined for antiarrhythmic activity. The compounds were…”
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