Search Results - "Hanna, Nardeen"
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1174 Costimulatory IgM T-cell engagers with enhanced and durable cytotoxicity
Published in Journal for immunotherapy of cancer (01-11-2023)“…BackgroundT-cell engagers (TCEs) have established their therapeutic value in treatment of various cancers by harnessing the power of immune system against…”
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CD123 Directed IgM Antibody-based T-cell Engager, IGM-2537, Demonstrates Potent in vitro and in vivo Activity with Minimal Cytokine Release
Published in Blood (15-11-2022)Get full text
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Novel CD123xCD3 Bispecific Igm Antibody, Igm-2537, Potently Induces T-Cell Mediated Cytotoxicity of Acute Myeloid Leukemia Cells In Vivo and in Vitro with Minimal Cytokine Release
Published in Blood (02-11-2023)“…Introduction: New therapeutics are needed for the effective treatment of acute myeloid leukemia (AML), as standard chemotherapeutics are poorly tolerated and…”
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Abstract 2933: Novel CD123xCD3 bispecific IgM antibody, IGM-2537, potently induces T-cell mediated cytotoxicity of acute myeloid leukemia cells with minimal cytokine release
Published in Cancer research (Chicago, Ill.) (04-04-2023)“…Abstract Novel therapeutics are needed for the effective treatment of acute myeloid leukemia (AML), as standard chemotherapeutics are poorly tolerated and ~50%…”
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Abstract 6726: Costimulatory IgM T-cell engagers with enhanced and durable cytotoxicity
Published in Cancer research (Chicago, Ill.) (22-03-2024)“…Abstract T-cell engagers (TCEs) have established therapeutic effect in treatment of various cancers by harnessing the power of the immune system against tumors…”
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Journal Article