Search Results - "Hanna, Nabil"

Role of Ultrasound in Flexor Tendon Injuries of the Hand: A New Insight by Bekhet, Chris Nabil Hanna, Ghaffar, Maha Khaled Abdel, Nassef, Mohamed Amin, Khattab, Rasha Tolba

“…This study was aimed at validating the diagnostic accuracy of ultrasound (US) scans in pre-operative evaluation of flexor tendon injuries in the hand and to…”
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Discovery of anti-infective compounds against Mycobacterium marinum after biotransformation of simple natural stilbenes by a fungal secretome by Nitschke, Jahn, Huber, Robin, Vossio, Stefania, Moreau, Dimitri, Marcourt, Laurence, Gindro, Katia, Queiroz, Emerson F, Soldati, Thierry, Hanna, Nabil

“…(Mtb), the causative agent of tuberculosis, remains a serious threat to human health worldwide and the quest for new anti-tubercular drugs is an enduring and…”
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Transcriptional Responses of Dictyostelium discoideum Exposed to Different Classes of Bacteria by Lamrabet, Otmane, Melotti, Astrid, Burdet, Frédéric, Hanna, Nabil, Perrin, Jackie, Nitschke, Jahn, Pagni, Marco, Hilbi, Hubert, Soldati, Thierry, Cosson, Pierre

“…amoebae feed by ingesting bacteria, then killing them in phagosomes. Ingestion and killing of different bacteria have been shown to rely on largely different…”
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Antimycobacterial drug discovery using Mycobacteria-infected amoebae identifies anti-infectives and new molecular targets by Trofimov, Valentin, Kicka, Sébastien, Mucaria, Sabrina, Hanna, Nabil, Ramon-Olayo, Fernando, Del Peral, Laura Vela-Gonzalez, Lelièvre, Joël, Ballell, Lluís, Scapozza, Leonardo, Besra, Gurdyal S., Cox, Jonathan A. G., Soldati, Thierry

“…Tuberculosis remains a serious threat to human health world-wide, and improved efficiency of medical treatment requires a better understanding of the…”
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Identification of Anti- Mycobacterium and Anti- Legionella Compounds With Potential Distinctive Structural Scaffolds From an HD-PBL Using Phenotypic Screens in Amoebae Host Models by Hanna, Nabil, Kicka, Sébastien, Chiriano, Gianpaolo, Harrison, Christopher, Sakouhi, Hajer Ouertatani, Trofimov, Valentin, Kranjc, Agata, Nitschke, Jahn, Pagni, Marco, Cosson, Pierre, Hilbi, Hubert, Scapozza, Leonardo, Soldati, Thierry

“…Tubercular and are the causative agents of potentially fatal respiratory diseases due to their intrinsic pathogenesis but also due to the emergence of…”
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Zn 2+ Intoxication of Mycobacterium marinum during Dictyostelium discoideum Infection Is Counteracted by Induction of the Pathogen Zn 2+ Exporter CtpC by Hanna, Nabil, Koliwer-Brandl, Hendrik, Lefrançois, Louise H, Kalinina, Vera, Cardenal-Muñoz, Elena, Appiah, Joddy, Leuba, Florence, Gueho, Aurélie, Hilbi, Hubert, Soldati, Thierry, Barisch, Caroline

“…Macrophages use diverse strategies to restrict intracellular pathogens, including either depriving the bacteria of (micro)nutrients such as transition metals…”
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Targeted isolation of natural analogs of anti-mycobacterial hit compounds based on the metabolite profiling of a large collection of plant extracts by Kirchhoffer, Olivier Auguste, Nitschke, Jahn, Allard, Pierre-Marie, Marcourt, Laurence, David, Bruno, Grondin, Antonio, Hanna, Nabil, Queiroz, Emerson Ferreira, Soldati, Thierry, Wolfender, Jean-Luc

“…Antibiotics resistance is a clear threat to the future of current tuberculosis treatments like rifampicin, prompting the need for new treatment options in this…”
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Temporal genome-wide fitness analysis of Mycobacterium marinum during infection reveals the genetic requirement for virulence and survival in amoebae and microglial cells by Lefrançois, Louise H, Nitschke, Jahn, Wu, Huihai, Panis, Gaël, Prados, Julien, Butler, Rachel E, Mendum, Tom A, Hanna, Nabil, Stewart, Graham R, Soldati, Thierry

“…Tuberculosis remains the most pervasive infectious disease and the recent emergence of drug-resistant strains emphasizes the need for more efficient drug…”
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The Glutamic Acid Decarboxylase System of the New Species Brucella microti Contributes to Its Acid Resistance and to Oral Infection of Mice by Occhialini, Alessandra, de Bagüés, Maria Pilar Jiménez, Saadeh, Bashir, Bastianelli, Daniela, Hanna, Nabil, De Biase, Daniela, Köhler, Stephan

“…Background. Genome analysis indicated that the new species Brucella microti possesses a potentially functional glutamate decarboxylase (GAD) system involved in…”
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Rituximab-Mediated Cell Signaling and Chemo/Immuno-sensitization of Drug-Resistant B-NHL Is Independent of Its Fc Functions by Vega, Mario I., Huerta-Yepez, Sara, Martinez-Paniagua, Melisa, Martinez-Miguel, Bernardo, Hernandez-Pando, Rogelio, González-Bonilla, Cesar R., Chinn, Paul, Hanna, Nabil, Hariharan, Kandasamy, Jazirehi, Ali R., Bonavida, Benjamin

“…Purpose: Rituximab [chimeric anti-CD20 monoclonal antibody], alone or combined with chemotherapy, is used in the treatment of non–Hodgkin's lymphoma (NHL)…”
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Chimeric anti-CD20 (IDEC-C2B8) monoclonal antibody sensitizes a B cell lymphoma cell line to cell killing by cytotoxic drugs by Demidem, A, Lam, T, Alas, S, Hariharan, K, Hanna, N, Bonavida, B

“…More than 50% of patients with aggressive B lymphomas and the majority of patients with low grade lymphomas are not cured by current therapeutic strategies…”
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Antibody therapy of non-Hodgkin's B-cell lymphoma by Chinn, Paul, Braslawsky, Gary, White, Christine, Hanna, Nabil

“…Engineering antibodies with reduced immunogenicity and enhanced effector functions, and selecting antigen targets with the appropriate specificity, density,…”
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Elimination of Fc Receptor-Dependent Effector Functions of a Modified IgG4 Monoclonal Antibody to Human CD4 by Reddy, Manjula P, Kinney, Cheryl Ann S, Chaikin, Margery A, Payne, Angela, Fishman-Lobell, Jacqueline, Tsui, Ping, Dal Monte, Paul R, Doyle, Michael L, Brigham-Burke, Michael R, Anderson, Darrell, Reff, Mitchell, Newman, Roland, Hanna, Nabil, Sweet, Raymond W, Truneh, Alemseged

“…Several CD4 mAbs have entered the clinic for the treatment of autoimmune diseases or transplant rejection. Most of these mAbs caused CD4 cell depletion, and…”
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Distinct Mycobacterium marinum phosphatases determine pathogen vacuole phosphoinositide pattern, phagosome maturation, and escape to the cytosol by Koliwer‐Brandl, Hendrik, Knobloch, Paulina, Barisch, Caroline, Welin, Amanda, Hanna, Nabil, Soldati, Thierry, Hilbi, Hubert

“…The causative agent of tuberculosis, Mycobacterium tuberculosis, and its close relative Mycobacterium marinum manipulate phagocytic host cells, thereby…”
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Vacuolins and myosin VII are required for phagocytic uptake and phagosomal membrane recycling in Dictyostelium discoideum by Bosmani, Cristina, Leuba, Florence, Hanna, Nabil, Bach, Frauke, Burdet, Frédéric, Pagni, Marco, Hagedorn, Monica, Soldati, Thierry

“…Flotillins are lipid raft residents involved in membrane trafficking and recycling of plasma membrane proteins. uses phagocytosis to kill, digest and feed on…”
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Role of natural killer cells in control of cancer metastasis by Hanna, N

“…There is a close association between levels of natural killer (NK) cell activity and the ability of the host to eliminate circulating tumor cell emboli. Mice…”
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Mycobacterium marinum produces distinct mycobactin and carboxymycobactin siderophores to promote growth in broth and phagocytes by Knobloch, Paulina, Koliwer‐Brandl, Hendrik, Arnold, Fabian M., Hanna, Nabil, Gonda, Imre, Adenau, Sophia, Personnic, Nicolas, Barisch, Caroline, Seeger, Markus A., Soldati, Thierry, Hilbi, Hubert

“…Mycobacterium marinum is a model organism for pathogenic Mycobacterium species, including Mycobacterium tuberculosis, the causative agent of tuberculosis…”
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Zn2+ Intoxication of Mycobacterium marinum during Dictyostelium discoideum Infection Is Counteracted by Induction of the Pathogen Zn2+ Exporter CtpC by Hanna, Nabil, Koliwer-Brandl, Hendrik, Lefrançois, Louise H, Kalinina, Vera, Cardenal-Muñoz, Elena, Appiah, Joddy, Leuba, Florence, Gueho, Aurélie, Hilbi, Hubert, Soldati, Thierry, Barisch, Caroline

“…Macrophages use diverse strategies to restrict intracellular pathogens, including either depriving the bacteria of (micro)nutrients such as transition metals…”
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Global Rsh-dependent transcription profile of Brucella suis during stringent response unravels adaptation to nutrient starvation and cross-talk with other stress responses by Hanna, Nabil, Ouahrani-Bettache, Safia, Drake, Kenneth L, Adams, L Garry, Köhler, Stephan, Occhialini, Alessandra

“…In the intracellular pathogen Brucella spp., the activation of the stringent response, a global regulatory network providing rapid adaptation to…”
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Vacuolins and myosin VII are required for phagocytic uptake and phagosomal membrane recycling in Dictyostelium discoideum by Bosmani, Cristina, Leuba, Florence, Hanna, Nabil, Bach, Frauke, Burdet, Frédéric, Pagni, Marco, Hagedorn, Monica, Soldati, Thierry

“…Flotillins are lipid rafts residents involved in membrane trafficking and recycling of plasma membrane proteins. Dictyostelium discoideum uses phagocytosis to…”
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