Search Results - "Hanna, David A."

Heme dynamics and trafficking factors revealed by genetically encoded fluorescent heme sensors by Hanna, David A., Harvey, Raven M., Martinez-Guzman, Osiris, Yuan, Xiaojing, Chandrasekharan, Bindu, Raju, Gheevarghese, Outten, F. Wayne, Hamza, Iqbal, Reddi, Amit R.

“…Heme is an essential cofactor and signaling molecule. Heme acquisition by proteins and heme signaling are ultimately reliant on the ability to mobilize labile…”
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Regulation of intracellular heme trafficking revealed by subcellular reporters by Yuan, Xiaojing, Rietzschel, Nicole, Kwon, Hanna, Nuno, Ana Beatriz Walter, Hanna, David A., Phillips, John D., Raven, Emma L., Reddi, Amit R., Hamza, Iqbal

“…Heme is an essential prosthetic group in proteins that reside in virtually every subcellular compartment performing diverse biological functions. Irrespective…”
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A growth chamber for chronic exposure of mammalian cells to H2S by Hanna, David A., Vitvitsky, Victor, Banerjee, Ruma

“…H2S is a redox-active signaling molecule that exerts an array of cellular and physiological effects. While intracellular H2S concentrations are estimated to be…”
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Handling heme: The mechanisms underlying the movement of heme within and between cells by Donegan, Rebecca K., Moore, Courtney M., Hanna, David A., Reddi, Amit R.

“…Heme is an essential cofactor and signaling molecule required for virtually all aerobic life. However, excess heme is cytotoxic. Therefore, heme must be safely…”
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Rapid HPLC method reveals dynamic shifts in coenzyme Q redox state by Vitvitsky, Victor, Kumar, Roshan, Diessl, Jutta, Hanna, David A., Banerjee, Ruma

“…Ubiquinol or coenzyme Q (CoQ) is a lipid-soluble electron carrier in the respiratory chain and an electron acceptor for various enzymes in metabolic pathways…”
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Heme Gazing: Illuminating Eukaryotic Heme Trafficking, Dynamics, and Signaling with Fluorescent Heme Sensors by Hanna, David A, Martinez-Guzman, Osiris, Reddi, Amit R

“…Heme (iron protoporphyrin IX) is an essential protein prosthetic group and signaling molecule required for most life on Earth. All heme-dependent processes…”
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H2S preconditioning induces long-lived perturbations in O2 metabolism by Hanna, David A, Diessl, Jutta, Guha, Arkajit, Kumar, Roshan, Andren, Anthony, Lyssiotis, Costas, Banerjee, Ruma

“…Hydrogen sulfide exposure in moderate doses can induce profound but reversible hypometabolism in mammals. At a cellular level, H2S inhibits the electron…”
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H 2 S preconditioning induces long-lived perturbations in O 2 metabolism by Hanna, David A, Diessl, Jutta, Guha, Arkajit, Kumar, Roshan, Andren, Anthony, Lyssiotis, Costas, Banerjee, Ruma

“…Hydrogen sulfide exposure in moderate doses can induce profound but reversible hypometabolism in mammals. At a cellular level, H S inhibits the electron…”
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Hydrogen sulfide stimulates lipid biogenesis from glutamine that is dependent on the mitochondrial NAD(P)H pool by Carballal, Sebastian, Vitvitsky, Victor, Kumar, Roshan, Hanna, David A., Libiad, Marouane, Gupta, Aditi, Jones, Jace W., Banerjee, Ruma

“…Mammalian cells synthesize H2S from sulfur-containing amino acids and are also exposed to exogenous sources of this signaling molecule, notably from gut…”
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Heme bioavailability and signaling in response to stress in yeast cells by Hanna, David A., Hu, Rebecca, Kim, Hyojung, Martinez-Guzman, Osiris, Torres, Matthew P., Reddi, Amit R.

“…Protoheme (hereafter referred to as heme) is an essential cellular cofactor and signaling molecule that is also potentially cytotoxic. To mitigate heme…”
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Heme oxygenase-2 (HO-2) binds and buffers labile ferric heme in human embryonic kidney cells by Hanna, David A., Moore, Courtney M., Liu, Liu, Yuan, Xiaojing, Dominic, Iramofu M., Fleischhacker, Angela S., Hamza, Iqbal, Ragsdale, Stephen W., Reddi, Amit R.

“…Heme oxygenases (HOs) detoxify heme by oxidatively degrading it into carbon monoxide, iron, and biliverdin, which is reduced to bilirubin and excreted. Humans…”
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Depletion assisted hemin affinity (DAsHA) proteomics reveals an expanded landscape of heme-binding proteins in the human proteome by Kim, Hyojung, Moore, Courtney M, Mestre-Fos, Santi, Hanna, David A, Williams, Loren Dean, Reddi, Amit R, Torres, Matthew P

“…Abstract Heme b (iron protoporphyrin IX) plays important roles in biology as a metallocofactor and signaling molecule. However, the targets of heme signaling…”
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Fluorometric Methods to Measure Bioavailable and Total Heme by Dominic, Iramofu M, Willoughby, Mathilda M, Freer, Abigail K, Moore, Courtney M, Donegan, Rebecca K, Martinez-Guzman, Osiris, Hanna, David A, Reddi, Amit R

“…Heme b (iron protoporphyrin IX) is an essential but potentially cytotoxic cofactor, signaling molecule, and nutritional source of iron. Its importance in cell…”
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A growth chamber for chronic exposure of mammalian cells to H 2 S by Hanna, David A, Vitvitsky, Victor, Banerjee, Ruma

“…H S is a redox-active signaling molecule that exerts an array of cellular and physiological effects. While intracellular H S concentrations are estimated to be…”
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