Search Results - "Hanna, Atef G"

A Comprehensive Overview of the Developments of Cdc25 Phosphatase Inhibitors by Abdelwahab, Ahmed Bakr, El-Sawy, Eslam Reda, Hanna, Atef G, Bagrel, Denyse, Kirsch, Gilbert

“…Cdc25 phosphatases have been considered promising targets for anticancer development due to the correlation of their overexpression with a wide variety of…”
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Synthesis and biological evaluation of novel 5-chloro-N-(4-sulfamoylbenzyl) salicylamide derivatives as tubulin polymerization inhibitors by Galal, Alaaeldin M. F, Soltan, Maha M, Ahmed, Esam R, Hanna, Atef G

“…A novel series of sulfonamide derivatives, coupled with a salicylamide scaffold, was designed and synthesized. The structures of the synthesized compounds were…”
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Configuration and molecular structure of 5-chloro-N-(4-sulfamoylbenzyl) salicylamide derivatives by Galal, Alaaeldin M.F., Atta, Diaa, Abouelsayed, Ahmed, Ibrahim, Medhat A., Hanna, Atef G.

“…A systematic study on sulfonamide derivatives with salicylamide core is presented for possible use in pharmaceutical applications. The molecular structure of…”
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Design, synthesis and antitumor activity of novel D-glucuronic acid derivatives by el-Nezhawy, Ahmed O H, Adly, Frady G, Eweas, Ahmed F, Hanna, Atef G, el-Kholy, Yehya M, el-Syed, Shahenaz H, el-Naggar, Tarek B A

“…A series of D-glucuronic acid derivatives were chemically synthesized including acetylated and deacetylated glucuronamides, as well as N-glucuronides starting…”
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Development, synthesis, and biological evaluation of sulfonyl‐α‐l‐amino acids as potential anti‐Helicobacter pylori and IMPDH inhibitors by Galal, Alaaeldin M. F., Mohamed, Hanaa S., Abdel‐Aziz, Marwa M., Hanna, Atef G.

“…Inosine 5ʹ‐monophosphate dehydrogenase (IMPDH) catalyzes a crucial step in the biosynthesis of DNA and RNA, and it has been exploited as a promising target for…”
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Structure and absolute configuration of some 5-chloro-2-methoxy-N-phenylbenzamide derivatives by Galal, Alaaeldin M F, Shalaby, Elsayed M., Abouelsayed, Ahmed, Ibrahim, Medhat A., Al-Ashkar, Emad, Hanna, Atef G

“…The absolute configuration of 5-chloro-2-methoxy-N-phenylbenzamide single crystal [compound (1)] and the effect of introducing –[CH2]n–, n=1,2 group adjacent…”
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In vitro chemotherapeutic and antiangiogenic properties of cardenolides from Acokanthera oblongifolia (Hochst.) Codd by Soltan, Maha M., Abd-Alla, Howaida I., Hassan, Amal Z., Hanna, Atef G.

“…Acovenoside A (Acov-A) and acobioside A (Acob-A) were isolated from . Their anticancer properties were explored regarding, antiproliferative and antiangiogenic…”
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Cardenolides and pentacyclic triterpenes isolated from Acokanthera oblongifolia leaves: their biological activities with molecular docking study by Abd-Alla, Howaida I., Soltan, Maha M., Hassan, Amal Z., Taie, Hanan A. A., Abo-Salem, Heba M., Karam, Eman A., El-Safty, Mounir M., Hanna, Atef G.

“…Pentacyclic triterpenes and cardenolides were isolated from leaves. Their chemical structures were determined based on comprehensive 1D and 2D NMR…”
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Phytochemical and antimicrobial investigation of the leaves of five Egyptian mango cultivars and evaluation of their essential oils as preservatives materials by Ouf, Salama A., Galal, Alaaeldin M. F., Ibrahim, Heba S., Hassan, Amal Z., Mekhael, Maged K. G., El-Yasergy, Khaled F., El-Ghany, Mohamed N. Abd, Rizk, Mohamed A., Hanna, Atef G.

“…The sterols, hydrocarbons and fatty acids constituents of the leaves of five mango cultivars locally implanted in Egypt were identified. The effect of their…”
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Synthesis and biological activity of new 18β-glycyrrhetinic acid derivatives by Radwan, Mohamed O., Ismail, Mohamed A.H., El-Mekkawy, Sahar, Ismail, Nasser S.M., Hanna, Atef G.

“…In an attempt to find out new, potent and safe anti-inflammatory molecules and as a contribution in the chemistry of triterpenes, a series of…”
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Cytotoxicity of multicellular cancer spheroids, antibacterial, and antifungal of selected sulfonamide derivatives coupled with a salicylamide and/or anisamide scaffold by Galal, Alaaeldin M. F., Fayad, Walid, Mettwally, Walaa S. A., Gomaa, Sanaa K., Ahmed, Esam R., El-Refai, Heba A., Hanna, Atef G.

“…In an attempt to overcome the drawbacks of the cancer monolayers model (2D), the 3-dimensional (3D) multicellular cancer spheroids (MCS) have been developed…”
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Synthesis of Some Novel D-Glucuronic Acid Acetylated Derivatives as Potential Anti-Tumor Agents by El-Nezhawy, Ahmed O. H., Adly, Frady G., Eweas, Ahmed F., Hanna, Atef G., El-Kholy, Yehya M., El-Sayed, Shahenaz H., El-Naggar, Tarek B. A.

“…A structurally diverse series of Δ4,5‐uronamide derivatives have been chemically synthesized starting from D‐glucuronic acid itself by means of acetylation,…”
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Four butyrolactones and diverse bioactive secondary metabolites from terrestrial Aspergillus flavipes MM2: isolation and structure determination by Nagia, Mohamed MS, El-Metwally, Mohammad Magdy, Shaaban, Mohamed, El-Zalabani, Soheir M, Hanna, Atef G

“…The chemical constituents and biological activities of the terrestrial Aspergillus flavipes MM2 isolated from Egyptian rice hulls are reported. Seven bioactive…”
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Dendrophen, a Novel Glycyrrhetyl Amino Acid from Dendronephthya hemprichi by Shaaban, Mohamed, Shaaban, Khaled A., Abd-Alla, Howaida I., Hanna, Atef G., Laatsch, Hartmut

“…Chemical investigation of the extract of Dendronephthya hemprichi, collected from the Red Sea, Egypt, delivered dendrophen (1), the first 3β…”
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Dendrophen, a Novel Glycyrrhetyl Amino Acid from Dendronephthya hemprichi by Shaaban, M., Shaaban, K. A., Abd-Alla, H. I., Hanna, A. G., Laatsch, H.

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Two cardenolides from Calotropis procera by Hanna, Atef G., Elgamal, M. Hani A., Morsy, Nagy A. M., Duddeck, Helmut, Kovács, József, Tóth, Gábor

“…Two cardiotonic glycosides were isolated from Calotropois procera; one of them (1) is a new natural product. Their structures were elucidated by extensive…”
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Structure of a calotropagenin-derived artifact from Calotropis procera by Hanna, Atef G., Shalaby, Nagwa M. M., Morsy, Nagy A. M., Simon, András, Tóth, Gábor, Malik, Shahid, Duddeck, Helmut

“…Isolation of a new artifact (1) from Calotropis procera is reported which, apparently, is formed from the precursor calotropagenin (4) when exposed to methanol…”
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Complete [formula omitted] and [formula omitted] signal assignments of 5α-cardenolides isolated from Calotropis procera R. BR by Elgamal, M.Hani A, Hanna, Atef G, Morsy, Nagy A.M, Duddeck, Helmut, Simon, András, Gáti, Tamás, Tóth, Gábor

“…Four cardenolides were isolated from Calotropis procera. Their structure and conformational behaviour were investigated by the extensive application of one-…”
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Two cardenolides fromCalotropis procera by Hanna, Atef G., Elgamal, M. Hani A., Morsy, Nagy A. M., Duddeck, Helmut, Kovács, József, Tóth, Gábor

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Complete1H and13C signal assignments of 5β-cardenolides isolated fromAcokanthera spectabilis Hook F by Hanna, Atef G., Elgamal, M. Hani A., Hassan, Amal Z., Duddeck, Helmut, Simon, András, Kovács, József, Tóth, Gábor

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