Search Results - "Hann, I"

Treatment strategy and long-term results in paediatric patients treated in consecutive UK AML trials by Gibson, B E S, Wheatley, K, Hann, I M, Stevens, R F, Webb, D, Hills, R K, De Graaf, S S N, Harrison, C J

“…Between 1988 and 2002, 758 children with acute myeloid leukaemia (AML) were treated on Medical Research Council (MRC) AML 10 and AML 12. MRC AML 10 tested the…”
Get full text

Outcome of relapsed infant acute lymphoblastic leukemia treated on the interfant-99 protocol by Driessen, E M C, de Lorenzo, P, Campbell, M, Felice, M, Ferster, A, Hann, I, Vora, A, Hovi, L, Escherich, G, Li, C K, Mann, G, Leblanc, T, Locatelli, F, Biondi, A, Rubnitz, J, Schrappe, M, Silverman, L, Stary, J, Suppiah, R, Szczepanski, T, Valsecchi, M, Pieters, R

Get full text

A randomized comparison of liposomal versus conventional amphotericin B for the treatment of pyrexia of unknown origin in neutropenic patients by Prentice, H. G., Hann, I. M., Herbrecht, R, Aoun, M, Kvaloy, S., Catovsky, D., Pinkerton, C. R., Schey, S. A., Jacobs, F, Oakhill, A., Stevens, R. F., Darbyshire, P. J., Gibson, B. E. S.

“…One hundred and thirty‐four adults and 204 children were randomized in two prospective, parallel comparative multicentre trials to receive either conventional…”
Get full text

Outcome of relapsed infant acute lymphoblastic leukemia treated on the interfant-99 protocol by Driessen, E M C, de Lorenzo, P, Campbell, M, Felice, M, Ferster, A, Hann, I, Vora, A, Hovi, L, Escherich, G, Li, C K, Mann, G, Leblanc, T, Locatelli, F, Biondi, A, Rubnitz, J, Schrappe, M, Silverman, L, Stary, J, Suppiah, R, Szczepanski, T, Valsecchi, M, Pieters, R

“…This corrects the article DOI: 10.1038/leu.2015.246…”
Get full text

CNS-Directed Therapy for Childhood Acute Lymphoblastic Leukemia: Childhood ALL Collaborative Group Overview of 43 Randomized Trials by CLARKE, M, GAYNON, P, HANN, I, HARRISON, G, MASERA, G, PETO, R, RICHARDS, S

“…A collaborative meta-analysis was performed to clarify the relative effects on relapse and survival of different types of therapies directed at the CNS in…”
Get full text

Down's syndrome and acute lymphoblastic leukaemia: clinical features and response to treatment by Chessells, J M, Harrison, G, Richards, S M, Bailey, C C, Hill, F G H, Gibson, B E, Hann, I M

“…AIMS To examine the clinical and biological features of acute lymphoblastic leukaemia in children with Down's syndrome (DS), to compare their survival with…”
Get full text

A comparison of outcome from febrile neutropenic episodes in children compared with adults: results from four EORTC studies by Hann, I., Viscoli, C., Paesmans, M., Gaya, H., Glauser, M.

“…The object of this study was to determine whether there were any differences between the ‘typical’ child with fever and neutropenia and their adult counterpart…”
Get full text

Determinants of outcome after intensified therapy of childhood lymphoblastic leukaemia: results from Medical Research Council United Kingdom acute lymphoblastic leukaemia XI protocol by Hann, Ian, Vora, Ajay, Harrison, Georgina, Harrison, Christine, Eden, Osborn, Hill, Frank, Gibson, Brenda, Richards, Sue

“…The single most important prognostic determinant in childhood acute lymphoblastic leukaemia (ALL) is effective therapy and changes in therapy may influence the…”
Get full text

Long-term follow-up of the United Kingdom Medical Research Council protocols for childhood acute lymphoblastic leukaemia, 1980-1997 by EDEN, O. B, HARRISON, G, RICHARDS, S, LILLEYMAN, J. S, BAILEY, C. C, CHESSELLS, J. M, HANN, I. M, HILL, F. G. H, GIBSON, B. E. S

“…Results of three consecutive completed UK trials (1980-1997) for childhood lymphoblastic leukaemia are presented. National accrual has progressively increased…”
Get full text

Clinical features, cytogenetics and outcome in acute lymphoblastic and myeloid leukaemia of infancy: report from the MRC Childhood Leukaemia working party by CHESSELLS, J. M, HARRISON, C. J, KEMPSKI, H, WEBB, Dkii, WHEATLEY, K, HANN, I. M, STEVENS, R. F, HARRISON, G, GIBSON, B. E

“…The clinical features, cytogenetics and response to treatment have been examined in 180 infants (aged <1 year) with acute leukaemia; 118 with acute…”
Get full text

Pediatric myelodysplasia : a study of 68 children and a new prognostic scoring system by PASSMORE, S. J, HANN, I. M, STILLER, C. A, RAMANI, P, SWANSBURY, G. J, GIBBONS, B, REEVES, B. R, CHESSELLS, J. M

“…Clinical, morphologic, and cytogenetic features were examined in a group of 68 children with myelodysplasia (MDS) referred to a single institution between…”
Get full text

Progressive reduction in treatment‐related deaths in Medical Research Council childhood lymphoblastic leukaemia trials from 1980 to 1997 (UKALL VIII, X and XI) by Hargrave, D. R., Hann, I. M., Richards, S. M., Hill, F. G., Lilleyman, J. S., Kinsey, S., Bailey, C. C., Chessells, J. M., Mitchell, C., Eden, O. B.

“…In the last 20 years, the survival rate for children with acute lymphoblastic leukaemia (ALL) has markedly improved, largely owing to a decrease in relapses…”
Get full text

Outcome for children with relapsed acute myeloid leukaemia following initial therapy in the medical research council (MRC) AML 10 trial by WEBB, D. K. H, WHEATLEY, K, HARRISON, G, STEVENS, R. F, HANN, I. M

Get full text

Haematological abnormalities in Shwachman-Diamond syndrome by Smith, O P, Hann, I M, Chessells, J M, Reeves, B R, Milla, P

“…We have analysed the haematological parameters in 21 patients with Shwachman-Diamond syndrome (SDS) seen over a 25-year period at our institution. Neutropenia,…”
Get more information

Outcome of relapsed or refractory childhood B‐cell acute lymphoblastic leukaemia and B‐cell non‐Hodgkin's lymphoma treated with the UKCCSG 9003/9002 protocols by Atra, A., Gerrard, M., Hobson, R., Imeson, J. D., Hann, I. M., Pinkerton, C. R.

“…Twenty‐six children with B‐cell acute lymphoblastic leukaemia (B‐ALL) or Murphy Stage III or IV B‐cell non‐Hodgkin's lymphoma (B‐NHL) progressed or relapsed…”
Get full text

Improved outcome in children with advanced stage B-cell non-Hodgkin's lymphoma (B-NHL): results of the United Kingdom Children Cancer Study Group (UKCCSG) 9002 protocol by ATRA, A, IMESON, J. D, HOBSON, R, GERRARD, M, HANN, I. M, EDEN, O. B, CARTER, R. L, PINKERTON, C. R

“…From July 1990 to March 1996, 112 children with stage III or IV B-cell non-Hodgkin's lymphoma (B-NHL) with up to 70% FAB L3-type blasts (n = 42) in the bone…”
Get full text

Central venous access devices in children with congenital coagulation disorders: complications and long‐term outcome by McMahon, C., Smith, J., Khair, K., Liesner, R., Hann, I. M., Smith, O. P.

“…Reliable venous access is essential to facilitate the administration of prophylactic factor concentrate or blood products in children with congenital…”
Get full text

Improved outcome of acute myeloid leukaemia in Down’s syndrome by Craze, J L, Harrison, G, Wheatley, K, Hann, I M, Chessells, J M

“…OBJECTIVE To review the clinical features, treatment, and outcome of children in the UK with Down’s syndrome and acute myeloid leukaemia (AML). DESIGN A…”
Get full text

HLA-DPβ1 Asp84-Lys69 antigen-binding signature predicts event-free survival in childhood B-cell precursor acute lymphoblastic leukaemia: results from the MRC UKALL XI childhood ALL trial by Taylor, G M, Wade, R, Hussain, A, Thompson, P, Hann, I, Gibson, B, Eden, T, Richards, S

“…We previously reported that children in the UKALL XI ALL trial with HLA-DP 1 and -DP 3 supertypes had significantly worse event-free survival (EFS) than…”
Get full text

A simple, robust, validated and highly predictive index for the determination of risk‐directed therapy in acute myeloid leukaemia derived from the MRC AML 10 trial by Wheatley, Keith, Burnett, Alan K., Goldstone, Anthony H., Gray, Richard G., Hann, Ian M., Harrison, Christine J., Rees, John K. H., Stevens, Richard F., Walker, Helen

“…Data on 1711 patients, aged up to 55 years, in the MRC AML 10 trial were used to create a prognostic index for use in risk‐directed therapy decision making for…”
Get full text