Search Results - "Hanley, MR"

Thapsigargin inhibits the sarcoplasmic or endoplasmic reticulum Ca-ATPase family of calcium pumps by LYTTON, J, WESTLIN, M, HANLEY, M. R

“…The role of ATP-dependent calcium uptake into intracellular storage compartments is an essential feature of hormonally induced calcium signaling. Thapsigargin,…”
Get full text

Diverse molecular provocation of programmed cell death by Wertz, Ingrid E., Hanley, Michael R.

“…The experimental study and manipulation of programmed cell death has been greatly assisted by the identification of genetic and pharmacological tools that can…”
Get full text

Calcium Influx Factor Is Synthesized by Yeast and Mammalian Cells Depleted of Organellar Calcium Stores by Csutora, Peter, Su, Zhengchang, Kim, Hak Yong, Bugrim, Andrej, Cunningham, Kyle W., Nuccitelli, Richard, Keizer, Joel E., Hanley, Michael R., Blalock, J. Edwin, Marchase, Richard B.

“…Depletion of endoplasmic reticulum Ca2+stores leads to the entry of extracellular Ca2+into the cytoplasm, a process termed capacitative or store-operated…”
Get full text

Metabolism and biological activities of inositol pentakisphosphate and inositol hexakisphosphate by Sasakawa, Nobuyuki, Sharif, Mohammed, Hanley, Michael R.

Get full text

Evaluation of Calcium Influx Factors from Stimulated Jurkat T-lymphocytes by Microinjection into Xenopus Oocytes by Thomas, D, Hanley, M R

“…Acid extracts of thapsigargin-activated Jurkat cells have been shown to have intracellular activity in inducing a dose-dependent rapid chloride current upon…”
Get full text

Effect of capsaicin on the rabbit urinary bladder. What is the function of sensory nerves that contain substance P? by Harrison, S C, Ferguson, D R, Hanley, M R

“…The sensory innervation of the rabbit urinary bladder was studied using local application of the specific sensory neurotoxin capsaicin…”
Get more information

The mas oncogene encodes an angiotensin receptor by Jackson, T. R, Blair, L. A. C, Marshall, J, Goedert, M, Hanley, M. R

“…The class of receptors coupled to GTP-binding proteins share a conserved structural motif which is described as a 'seven-transmembrane segment' following the…”
Get full text

17 β-estradiol stimulates substance P receptor gene expression by Villablanca, Amparo C, Hanley, Michael R

“…The actions of substance P (SP), a widely distributed tachykinin neuropeptide, are mediated by the NK1 receptor, a seven trans-membrane spanning domain cell…”
Get full text

Lithium amplifies agonist-dependent phosphatidylinositol responses in brain and salivary glands by Berridge, M J, Downes, C P, Hanley, M R

“…1. The effect of Li+ on the agonist-dependent metabolism of [3H]inositol has been studied in rat brain, rat parotid and the insect salivary gland. 2. When…”
Get full text

Multiple embolic events in a patient with heparin induced thrombocytopaenic thrombotic syndrome and mural thrombus by BENNETT, G, HANLEY, M. R

“…This report describes a 55-year-old man admitted for renal colic and found to have an infarcted right kidney, for which he was treated with heparin…”
Get full text

Peptide receptors. Stepping up the pressure by Sharif, M, Hanley, M R

Get full text

Proto-oncogenes in the nervous system by Hanley, M R

Get more information

Functional characterization by heterologous expression of a novel cloned tachykinin peptide receptor by Donaldson, L F, Haskell, C A, Hanley, M R

“…An orphan receptor resembling the neurokinin 3 tachykinin receptor (NK3), initially claimed to be an atypical opioid receptor, is shown herein to respond…”
Get full text

Chromatographic resolution of an intracellular calcium influx factor from thapsigargin-activated Jurkat cells. Evidence for multiple activities influencing calcium elevation in Xenopus oocytes by Kim, H Y, Thomas, D, Hanley, M R

“…Acid extracts of thapsigargin-stimulated Jurkat cells revealed both intracellular and extracellular activities stimulating Ca(2+)-dependent Cl- currents on…”
Get full text

Regulation of c-fos and c-jun Protooncogene Expression by the Ca2+- ATPase Inhibitor Thapsigargin by Schonthal, Axel, Sugarman, Jeff, Brown, Joan Heller, Hanley, Michael R., Feramisco, James R.

“…Thapsigargin, a non-phorbol-ester-type tumor promoter, discharges intracellular Ca2+stores by specific inhibition of the endoplasmic reticulum Ca2+-ATPase. We…”
Get full text

Inducible receptors by Donaldson, Lucy F., Hanley, Michael R., Villablanca, Amparo C.

“…While regulation of receptor function is known to occur at many levels (e.g. transcriptional, post-translational), it is generally perceived that a tissue…”
Get full text

Attenuation of agonist-induced desensitization of the rat substance P receptor by progressive truncation of the C-terminus by Sasakawa, Nobuyuki, Sharif, Mohammed, Hanley, Michael R.

“…We have investigated the C-terminal tail of the rat substance P receptor (SPR) as a domain essential for agonist-induced desensitization. Four progressively…”
Get full text

Inducible receptors by Donaldson, L.F., Hanley, M.R., Villablanca, A.C.

“…While regulation of receptor function is known to occur at many levels (e.g. transcriptional, post-translational), it is generally perceived that a tissue…”
Get full text

Rats go with the (urine) flow by Hanley, Michael R

“…A new study describes the correction of a rat model for inherited diabetes insipidus by gene therapy in the central nervous system…”
Get full text

Regulation of inositol trisphosphate-induced membrane currents in Xenopus oocytes by a Jurkat cell calcium influx factor by Thomas, D, Kim, H Y, Hanley, M R

“…The functional interactions of a Jurkat cell-derived calcium influx factor (CIF) with Ins(1,4,5)P3 were examined by microinjection and voltage-clamp recording…”
Get full text