Search Results - "Hanks, Adrianne N."
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Apoptosis Regulators and Responses in Human Melanocytic and Keratinocytic Cells
Published in Journal of investigative dermatology (01-01-2003)“…Apoptosis in keratinocytes is required for epidermal turnover, stratum corneum formation, and removal of ultraviolet-damaged premalignant cells. Its role in…”
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Activation of Dual Apoptotic Pathways in Human Melanocytes and Protection by Survivin
Published in Journal of investigative dermatology (01-10-2006)“…Apoptosis resistance in melanoma is a primary cause of treatment failure. Apoptotic pathways in melanocytes, from which melanoma arises, are poorly…”
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Melanocyte expression of survivin promotes development and metastasis of UV-induced melanoma in HGF-transgenic mice
Published in Cancer research (Chicago, Ill.) (01-06-2007)“…We previously found the apoptosis inhibitor Survivin to be expressed in melanocytic nevi and melanoma but not in normal melanocytes. To investigate the role of…”
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Limited gene activation in tumor and normal epithelial cells treated with the DNA methyltransferase inhibitor 5-aza-2'-deoxycytidine
Published in Molecular pharmacology (01-01-2004)“…It remains unclear to what extent drugs targeting transcriptional repressor complexes affect global gene expression in cells derived from target and nontarget…”
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UVB-induced apoptosis drives clonal expansion during skin tumor development
Published in Carcinogenesis (New York) (01-01-2005)“…The mechanism by which a single mutant cell clonally expands is usually assumed to involve an additional mutation in a cell cycle regulatory gene. An…”
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Proliferation, apoptosis, and survivin expression in keratinocytic neoplasms and hyperplasias
Published in The American journal of dermatopathology (01-06-2004)“…The dysregulation of apoptosis occurs in many cutaneous disease states. Several apoptosis inhibitors have been shown elevated in neoplasms and in some…”
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Survivin expression in mouse skin prevents papilloma regression and promotes chemical-induced tumor progression
Published in Cancer research (Chicago, Ill.) (01-02-2003)“…Induction of cutaneous squamous cell carcinoma (SCC) in mice, by topical chemical [9,10-dimethylbenzanthracene (DMBA) and phorbol 12-myristate 13-acetate…”
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Adhesion receptor expression by CD34 + cells from peripheral blood or bone marrow grafts: Correlation with time to engraftment
Published in Experimental hematology (01-05-2006)“…This study was undertaken to define the pattern of cell adhesion receptor expression by the CD34 + progenitor cells from mobilized peripheral blood and bone…”
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Proliferation, apoptosis, and survivin expression in a spectrum of melanocytic nevi
Published in Journal of cutaneous pathology (01-01-2005)“…Background: Apoptosis is important for maintenance of tissue homeostasis and often dysregulated in cutaneous neoplasms. The apoptosis inhibitor survivin is…”
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Very Late Antigen-4 (VLA-4) Expression by AML Blasts: Correlation of VCAM-1 Binding to Overall Survival
Published in Blood (16-11-2005)“…Adhesion of acute myeloid leukemia (AML) blasts in the bone marrow (BM) microenvironment is known to protect the cells from chemotherapy-induced apoptosis…”
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In Vivo Chemotherapy Protection and Efficacy of Multidrug Resistance (MDR-1) Gene Transfer in a Patient with Refractory Non-Hodgkin's Lymphoma (NHL)
Published in Blood (16-11-2005)“…We report clinical and molecular data for the first subject enrolled in our gene therapy clinical trial. This patient had follicular transformed large cell…”
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