Search Results - "Hankin, Joseph A"

Sublimation as a Method of Matrix Application for Mass Spectrometric Imaging by Hankin, Joseph A., Barkley, Robert M., Murphy, Robert C.

“…Common organic matrix-assisted laser desorption/ionization (MALDI) matrices, 2,5-dihydroxybenzoic acid, 3,5-dimethoxy-4-hydroxycinnamic acid, and…”
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Imaging of lipid species by MALDI mass spectrometry by Murphy, Robert C., Hankin, Joseph A., Barkley, Robert M.

“…Recent developments in MALDI have enabled direct detection of lipids as intact molecular species present within cellular membranes. Abundant lipid-related ions…”
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MALDI Imaging of Lipid Biochemistry in Tissues by Mass Spectrometry by Zemski Berry, Karin A, Hankin, Joseph A, Barkley, Robert M, Spraggins, Jeffrey M, Caprioli, Richard M, Murphy, Robert C

“…Berry et al examine matrix-assisted laser desorption ionization (MALDI) imaging. They focus on MALDI with regard to of lipid biochemistry in tissues by mass…”
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Relationship between MALDI IMS Intensity and Measured Quantity of Selected Phospholipids in Rat Brain Sections by Hankin, Joseph A, Murphy, Robert C

“…MALDI IMS positive ion images of rat brain show a regional distribution of phosphocholine species that is striking in the apparent distinctiveness and…”
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Mass Spectrometric Collisional Activation and Product Ion Mobility of Human Serum Neutral Lipid Extracts by Hankin, Joseph A, Barkley, Robert M, Zemski-Berry, Karin, Deng, Yiming, Murphy, Robert C

“…A novel method for lipid analysis called CTS (collisional activation and traveling wave mass spectrometry), involving tandem mass spectrometry of all precursor…”
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MALDI Mass Spectrometric Imaging of Lipids in Rat Brain Injury Models by Hankin, Joseph A., Farias, Santiago E., Barkley, Robert M., Heidenreich, Kim, Frey, Lauren C., Hamazaki, Kei, Kim, Hee-Yong, Murphy, Robert C.

“…Matrix-assisted laser desorption ionization/ionization imaging mass spectrometry (MALDI IMS) with a time-of-flight analyzer was used to characterize the…”
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MALDI imaging MS of phospholipids in the mouse lung[S] by Berry, Karin A. Zemski, Li, Bilan, Reynolds, Susan D., Barkley, Robert M., Gijón, Miguel A., Hankin, Joseph A., Henson, Peter M., Murphy, Robert C.

“…Lipid mediators are important in lung biochemistry and are derived from the enzymatic oxidation of arachidonic and docosahexaenoic acids, which are PUFAs that…”
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Sphingolipid distribution changes with age in the human lens[S] by Deeley, Jane M., Hankin, Joseph A., Friedrich, Michael G., Murphy, Robert C., Truscott, Roger J.W., Mitchell, Todd W., Blanksby, Stephen J.

“…The formation of an internal barrier to the diffusion of small molecules in the lens during middle age is hypothesized to be a key event in the development of…”
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Major urinary metabolites of 6-keto-prostaglandin F2α in mice[S] by Kuklev, Dmitry V., Hankin, Joseph A., Uhlson, Charis L., Hong, Yu H., Murphy, Robert C., Smith, William L.

“…Western diets are enriched in omega-6 vs. omega-3 fatty acids, and a shift in this balance toward omega-3 fatty acids may have health benefits. There is…”
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A novel class of microbial phosphocholine‐specific phospholipases C by Stonehouse, Martin J., Cota‐Gomez, Adela, Parker, Sarah K., Martin, Wesley E., Hankin, Joseph A., Murphy, Robert C., Chen, Weibin, Lim, Kheng B., Hackett, Murray, Vasil, Adriana I., Vasil, Michael L.

“…Summary In this report we describe the 1500‐fold purification and characterization of the haemolytic phospholipase C (PLC) of Pseudomonas aeruginosa, the…”
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Tandem Mass Spectrometry in Combination with Product Ion Mobility for the Identification of Phospholipids by Berry, Karin A. Zemski, Barkley, Robert M, Berry, Joseph J, Hankin, Joseph A, Hoyes, Emmy, Brown, Jeffery M, Murphy, Robert C

“…Concerted tandem and traveling wave ion mobility mass spectrometry (CTS analysis) is a unique method that results in a four-dimensional data set including…”
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Lysophospholipid acyltransferases and eicosanoid biosynthesis in zebrafish myeloid cells by Zarini, Simona, Hankin, Joseph A., Murphy, Robert C., Gijón, Miguel A.

“…Eicosanoids derived from the enzymatic oxidation of arachidonic acid play important roles in a large number of physiological and pathological processes in…”
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Tandem Mass Spectrometry and Ion Mobility Reveals Structural Insight into Eicosanoid Product Ion Formation by Di Giovanni, James P., Barkley, Robert M., Jones, David N. M., Hankin, Joseph A., Murphy, Robert C.

“…Ion mobility measurements of product ions were used to characterize the collisional cross section (CCS) of various complex lipid [M-H] − ions using traveling…”
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Measurement of estradiol, estrone, and testosterone in postmenopausal human serum by isotope dilution liquid chromatography tandem mass spectrometry without derivatization by Wooding, Kerry M., Hankin, Joseph A., Johnson, Chris A., Chosich, Justin D., Baek, Sung W., Bradford, Andrew P., Murphy, Robert C., Santoro, Nanette

“…•We present a high-throughput sample preparation method for serum steroids.•We present a sensitive mass spectrometric method for quantitating steroids.•LOD,…”
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MALDI imaging of lipids after matrix sublimation/deposition by Murphy, Robert C., Hankin, Joseph A., Barkley, Robert M., Zemski Berry, Karin A.

“…Mass spectrometric techniques have been developed to record mass spectra of biomolecules including lipids as they naturally exist within tissues and thereby…”
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Ion mobility and tandem mass spectrometry of phosphatidylglycerol and bis(monoacylglycerol) phosphate (BMP) by Hankin, Joseph A., Murphy, Robert C., Barkley, Robert M., Gijón, Miguel A.

“…[Display omitted] •PG and BMP regioisomers were studied by tandem mass spectrometry with ion mobility.•Precursor ions of a PG and BMP isomeric pair were…”
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Chemistry and Thermochemistry of Silicon-Containing Anions in the Gas Phase by Damrauer, Robert, Hankin, Joseph A

“…Silicon anions studied in the gas-phase can be used to obtain a variety a basic thermochemical properties. The stability and reactivity of unusual…”
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Mechanism of Formation of the Major Estradiol Product Ions Following Collisional Activation of the Molecular Anion in a Tandem Quadrupole Mass Spectrometer by Wooding, Kerry M., Barkley, Robert M., Hankin, Joseph A., Johnson, Christopher A., Bradford, Andrew P., Santoro, Nanette, Murphy, Robert C.

“…The importance of the mass spectral product ion structure is highlighted in quantitative assays, which typically use multiple reaction monitoring (MRM), and in…”
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The lung tumor promoter, butylated hydroxytoluene (BHT), causes chronic inflammation in promotion-sensitive BALB/cByJ mice but not in promotion-resistant CXB4 mice by Bauer, Alison K, Dwyer-Nield, Lori D, Hankin, Joseph A, Murphy, Robert C, Malkinson, Alvin M

“…An inflammatory response accompanies the reversible pneumotoxicity caused by butylated hydroxytoluene (BHT) administration to mice. Lung tumor formation is…”
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Targeted over-expression of mPGES-1 and elevated PGE2 production is not sufficient for lung tumorigenesis in mice by Blaine, Stacy A., Meyer, Amy M., Hurteau, Greg, Wick, Marilee, Hankin, Joseph A., Murphy, Robert C., Dannenberg, Andrew J., Geraci, Mark W., Subbaramaiah, Kotha, Nemenoff, Raphael A.

“…There is a significant body of evidence suggesting that enzymes involved in arachidonic acid metabolism and their eicosanoid products play a role in various…”
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