Search Results - "Hank, Thomas"
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Local radicality and survival outcome of pancreatic cancer surgery
Published in Annals of gastroenterological surgery (01-09-2019)“…Pancreatic cancer remains a therapeutic challenge. Surgical resection in combination with systemic chemotherapy is the only option promising long‐term survival…”
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Prognostic Factors of Survival After Neoadjuvant Treatment and Resection for Initially Unresectable Pancreatic Cancer
Published in Annals of surgery (01-01-2021)“…MINIWe analyzed prognostic factors after neoadjuvant therapy and resection in 280 patients with initially unresectable pancreatic cancer—the largest…”
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Genome-wide genetic and epigenetic analyses of pancreatic acinar cell carcinomas reveal aberrations in genome stability
Published in Nature communications (06-11-2017)“…Pancreatic acinar cell carcinoma (ACC) is an aggressive exocrine tumor with largely unknown biology. Here, to identify potential targets for personalized…”
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Association Between Pancreatic Fistula and Long-term Survival in the Era of Neoadjuvant Chemotherapy
Published in JAMA surgery (01-10-2019)“…In the past decade, the use of neoadjuvant therapy (NAT) has increased for patients with borderline and locally advanced pancreatic ductal adenocarcinoma…”
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Conversion Surgery for Advanced Pancreatic Cancer
Published in Journal of clinical medicine (12-11-2019)“…While primarily unresectable locally advanced pancreatic cancer (LAPC) used to be an indication for palliative therapy, a strategy of neoadjuvant therapy (NAT)…”
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Imaging features of intraductal tubulopapillary neoplasm of the pancreas and its differentiation from conventional pancreatic ductal adenocarcinoma
Published in Scientific reports (16-09-2022)“…Intraductal tubulopapillary neoplasms (ITPN) are rare pancreatic tumors (< 1% of exocrine neoplasms) and are considered to have better prognosis than classical…”
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Diabetes mellitus is associated with unfavorable pathologic features, increased postoperative mortality, and worse long-term survival in resected pancreatic cancer
Published in Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.] (01-01-2020)“…The risk of pancreatic ductal adenocarcinoma (PDAC) is increased in patients with diabetes mellitus (DM), particularly in those with new-onset DM. However, the…”
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Prospective trial to evaluate the prognostic value of different nutritional assessment scores for survival in pancreatic ductal adenocarcinoma (NURIMAS Pancreas SURVIVAL)
Published in Journal of cachexia, sarcopenia and muscle (01-12-2021)“…Background Malnutrition is associated with poor survival in pancreatic cancer patients. Nutritional scores show great heterogeneity diagnosing malnutrition…”
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Impact of adjuvant therapy in patients with invasive intraductal papillary mucinous neoplasms of the pancreas
Published in Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.] (01-06-2020)“…There is limited data on the efficacy of adjuvant therapy (AT) in patients with invasive intraductal papillary mucinous neoplasms of the pancreas (IPMN). This…”
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Main Pancreatic Duct to Parenchymal Thickness Ratio at Preoperative Imaging is Associated with Overall Survival in Upfront Resected Pancreatic Cancer
Published in Annals of surgical oncology (01-05-2020)“…Background Pancreatic cancer induces parenchymal atrophy and duct dilation. The aim of this study was to evaluate whether these radiologic modifications are…”
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Microscopic size measurements in post‐neoadjuvant therapy resections of pancreatic ductal adenocarcinoma (PDAC) predict patient outcomes
Published in Histopathology (01-07-2020)“…Aims Pancreatic ductal adenocarcinomas (PDACs) are increasingly being treated with neoadjuvant therapy. However, the American Joint Committee on Cancer (AJCC)…”
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Recent Advances in Chromatin Mechanisms Controlling Pancreatic Carcinogenesis
Published in Epigenomes (01-06-2018)“…Pancreatic ductal adenocarcinoma has a heterogeneous genetic landscape, marked by frequent mutation of KRAS, CDKN2A, TP53, and SMAD4, resulting in poor…”
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Validation of the New R-Status Definitions (1mm margin) for Pancreatic Adenocarcinoma resected by Distal or Total Pancreatectomy
Published in Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.] (01-07-2017)“…Introduction: The definitions for R0 and R1 margin status after resection for pancreatic cancer are controversial. Patients & methods: A standardized protocol…”
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Encouraging observed 5-year survival with upfront resection and adjuvant therapy for pancreatic ductal adenocarcinoma in a large contemporary series
Published in Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.] (01-07-2017)“…Available data is restricted to series including patients over several decades with changes in standard therapy over time and one series of resection after…”
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Patient-reported Long-term Outcomes after Duodenum-preserving Pancreatic Head Resection (Berne Modification) for Chronic Pancreatitis
Published in Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.] (01-07-2017)“…Introduction: Duodenum-preserving pancreatic head resection (DPPHR) is one possible option for the surgical treatment of chronic pancreatitis (CP). With a…”
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Management of branch duct intraductal papillary mucinous neoplasms (BD-IPMN) of the pancreas: Single-center experience with 543 patients selected for resection or observation
Published in Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.] (01-07-2017)“…Conclusion: The management strategy advocated by the ICG of Fukuoka to classify BD-IPMN lesions shows a high accuracy with regard to HRS, but - in contrast -…”
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Case Report: A Rare Case of Esophagogastric Junctional Squamous Cell Carcinoma After the Successful Treatment of Neuroendocrine Carcinoma: Clonal Tumor Evolution Revealed by Genetic Analysis
Published in Frontiers in genetics (15-09-2021)“…Neuroendocrine carcinoma (NEC) of the esophagogastric junction (EGJ) is a rare disease with no established treatments. Herein, we describe a case of recurrent…”
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