Search Results - "Hanifi, Arezoo"
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1301 High-throughput analysis of immune biomarkers from brightfield whole tumor images using Indica Halo
Published in Journal for immunotherapy of cancer (01-11-2023)“…BackgroundA comprehensive understanding of the tumor microenvironment (TME) empowers researchers/scientists in the field of immuno-oncology to develop clinical…”
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51 A novel cross-site analysis of Vectra® Polaris™ multiplex fluorescence PD-1/PD-L1 immunohistochemistry on colorectal cancer with high and low microsatellite instability
Published in Journal for immunotherapy of cancer (01-11-2021)“…BackgroundColorectal cancer (CRC) is the third most diagnosed cancer in the United States with a projected 52,980 deaths in 2021.1 Microsatellite…”
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Abstract 434: Characterizing viral mRNA and immuno-protein expression in head and neck squamous cell carcinoma using a novel automated RNAscope™/Polaris™ integrated assay
Published in Cancer research (Chicago, Ill.) (01-07-2021)“…Abstract Background: Chronic viral infection can generate inflammatory microenvironments leading to neoplastic growth and cancer development. Cancer patients…”
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Phenotypic Characterization of the Immune Landscape in the Bone Marrow of Patients with Acute Myeloid Leukemia (AML) Using MultiOmyxTM Hyperplexed Immunofluorescence Assay
Published in Blood (13-11-2019)“…Background: Acute myeloid leukemia (AML) is a clinically and molecularly heterogeneous disorder. Bone marrow (BM) constitutes the home niche for leukemia cells…”
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Abstract 2143: Profiling exhausted T cells using Vectra® Polaris™multiplex immunofluorescence assay in HNSCC
Published in Cancer research (Chicago, Ill.) (15-08-2020)“…Abstract Background: Head and neck squamous cell carcinoma (HNSCC) is a cancer with the ability to modulate the immune system to evade detection. It is the…”
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Abstract 497: Characterization of TIGIT expression using MultiOmyxTM hyperplexed immunofluorescence assay in solid tumors
Published in Cancer research (Chicago, Ill.) (01-07-2019)“…Abstract TIGIT (T cell immunoreceptor with Ig and ITIM domains) is a recently identified immune-receptor that is expressed on T cells, natural killer (NK)…”
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Abstract 2352: Development of an AI-based algorithm to quantify eosinophils in H&E images from colorectal cancer (CRC) tissue sections guided by biomarker staining using multiplex immunofluorescence imaging
Published in Cancer research (Chicago, Ill.) (22-03-2024)“…Abstract Background: Eosinophils are innate immune granulocytes that migrate to areas of inflammation to combat against infection and disease. Best known for…”
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Abstract 2256: Efficient large-scale cell classification and analysis for MultiOmyxTMassays: A deep learning approach
Published in Cancer research (Chicago, Ill.) (01-07-2018)“…Abstract Traditional immunohistochemistry (IHC) techniques utilize one slide per biomarker. When clinical samples are precious and the number of serial…”
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Abstract 627: Custom Vectra® Polaris™ fluorescent multiplex IHC panel identifies mature tertiary lymphoid structures in colorectal cancer
Published in Cancer research (Chicago, Ill.) (15-06-2022)“…Abstract Introduction: Tertiary lymphoid structures (TLS) are promising prognostic indicators of positive outcomes for patients with solid tumors including…”
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IL-2 and IL-4 stimulate MEK1 expression and contribute to T cell resistance against suppression by TGF-beta and IL-10 in asthma
Published in The Journal of immunology (1950) (15-11-2010)“…The T cell-driven airway inflammation in chronic asthma is uninhibited and sustained. We examined the resistance of T cells from asthmatic patients against…”
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Mathematical modeling and analysis of asthma stability and severity
Published 01-01-2013“…Asthma is one of the most common chronic conditions in the United States. Asthma affects about one in fifteen people. It affects children more than adults and…”
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Dissertation -
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IL-2 and IL-4 Stimulate MEK1 Expression and Contribute to T Cell Resistance against Suppression by TGF-b and IL-10 in Asthma
Published in The Journal of immunology (1950) (15-11-2010)“…The T cell-driven airway inflammation in chronic asthma is uninhibited and sustained. We examined the resistance of T cells from asthmatic patients against…”
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Journal Article -
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A Linear Parametric Approach for Analysis of Mouse Respiratory Impedance
Published in IEEE transactions on biomedical circuits and systems (01-06-2012)“…Assessment of the lung mechanics is crucial in lung function studies. Commonly lung mechanics is achieved through measurement of the input impedance of the…”
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Journal Article