Search Results - "Haney, L."

Targeting the Isoprenoid Biosynthetic Pathway in Multiple Myeloma by Haney, Staci L, Holstein, Sarah A

“…Multiple myeloma (MM) is a plasma cell malignancy for which there is currently no cure. While treatment options for MM have expanded over the last two decades,…”
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Catalytically inactive Dnmt3b rescues mouse embryonic development by accessory and repressive functions by Nowialis, Pawel, Lopusna, Katarina, Opavska, Jana, Haney, Staci L., Abraham, Ajay, Sheng, Peike, Riva, Alberto, Natarajan, Amarnath, Guryanova, Olga, Simpson, Melanie, Hlady, Ryan, Xie, Mingyi, Opavsky, Rene

“…DNA methylation regulates gene expression in a variety of processes, including mouse embryonic development. Four catalytically active enzymes function in mice…”
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Development and Validation of an LC-MS/MS Assay for the Quantitation of MO-OH-Nap Tropolone in Mouse Plasma: Application to In Vitro and In Vivo Pharmacokinetic Studies by Aldhafiri, Wafaa N, Chhonker, Yashpal S, Ahmed, Nusrat, Singh, Sandeep K, Haney, Staci L, Ford, James B, Holstein, Sarah A, Murry, Daryl J

“…A rapid, selective, and sensitive liquid chromatography coupled with tandem mass spectrometry (LC-MS/MS) method was developed and validated for the…”
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Dnmt3a Is a Haploinsufficient Tumor Suppressor in CD8+ Peripheral T Cell Lymphoma by Haney, Staci L, Upchurch, G Michael, Opavska, Jana, Klinkebiel, David, Hlady, Ryan A, Roy, Sohini, Dutta, Samikshan, Datta, Kaustubh, Opavsky, Rene

“…DNA methyltransferase 3A (DNMT3A) is an enzyme involved in DNA methylation that is frequently mutated in human hematologic malignancies. We have previously…”
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Simultaneous Quantitation of Isoprenoid Pyrophosphates in Plasma and Cancer Cells Using LC-MS/MS by Chhonker, Yashpal S, Haney, Staci L, Bala, Veenu, Holstein, Sarah A, Murry, Daryl J

“…Isoprenoids (IsoP) are an important class of molecules involved in many different cellular processes including cholesterol synthesis. We have developed a…”
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Promoter Hypomethylation and Expression Is Conserved in Mouse Chronic Lymphocytic Leukemia Induced by Decreased or Inactivated Dnmt3a by Haney, Staci L., Upchurch, G. Michael, Opavska, Jana, Klinkebiel, David, Hlady, Ryan A., Suresh, Abhinav, Pirruccello, Samuel J., Shukla, Vipul, Lu, Runqing, Costinean, Stefan, Rizzino, Angie, Karpf, Adam R., Joshi, Shantaram, Swanson, Patrick, Opavsky, Rene

“…DNA methyltransferase 3a (DNMT3A) catalyzes the formation of 5-methyl-cytosine in mammalian genomic DNA, and it is frequently mutated in human hematologic…”
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Occult central nervous system involvement in patients with metastatic breast cancer: prevalence, predictive factors and impact on overall survival by Miller, K. D., Weathers, T., Haney, L. G., Timmerman, R., Dickler, M., Shen, J., Sledge Jr, G. W.

“…Background: As screening central nervous system (CNS) imaging is not routinely performed, the incidence and clinical relevance of occult CNS metastases in…”
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Recent Advances in the Development of Mammalian Geranylgeranyl Diphosphate Synthase Inhibitors by Haney, Staci L, Wills, Veronica S, Wiemer, David F, Holstein, Sarah A

“…The enzyme geranylgeranyl diphosphate synthase (GGDPS) catalyzes the synthesis of the 20-carbon isoprenoid geranylgeranyl diphosphate (GGPP). GGPP is the…”
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What are the Expectations for Length of Stay after Pediatric Lung Transplantation? by Thangappan, K., Haney, L., Zafar, F., Hossain, M., Zhang, Y., Steger, J., Schecter, M., Towe, C., Morales, D.L.

“…Pediatric lung transplantations (LTx) consists of a relatively small but significant population. Without pooling of multi-institutional data, setting…”
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Simple and Rapid Laboratory Method for Rewetting Dry Soil for Incubations by Haney, R.L, Haney, E.B

“…Soil microbial activity is greatly affected by soil water content. Determining the appropriate moisture content to rewet soils that have been dried in…”
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Methylation-independent repression of Dnmt3b contributes to oncogenic activity of Dnmt3a in mouse MYC-induced T-cell lymphomagenesis by Haney, S L, Hlady, R A, Opavska, J, Klinkebiel, D, Pirruccello, S J, Dutta, S, Datta, K, Simpson, M A, Wu, L, Opavsky, R

“…DNA methyltransferase 3A (DNMT3A) catalyzes cytosine methylation of mammalian genomic DNA. In addition to myeloid malignancies, mutations in DNMT3A have been…”
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Estimating Soil Carbon, Nitrogen, and Phosphorus Mineralization from Short-Term Carbon Dioxide Respiration by Haney, R.L, Brinton, W.H, Evans, Eric

“…The measurement of soil carbon dioxide (CO2) respiration is a means to gauge biological soil fertility. Test methods for respiration employed in the laboratory…”
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Stroke on Mechanical Support: Similar Survival but Higher Risk of Stroke Post-Transplant by Zafar, F., Haney, L., Riggs, K., Thangappan, K., Chen, S., Mehegan, M., VanderPluym, C., Peng, D., Lorts, A., Morales, D.L.

“…Ventricular assist devices (VADs) increase waitlist survival, yet the risk of stroke is not trivial. There is a knowledge gap regarding the impact of these…”
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What are the Expectations for Length of Stay after Pediatric Heart Transplantation? by Thangappan, K., Haney, L., Zafar, F., Hossain, M., Zhang, Y., Chin, C., Ryan, T.D., Lehenbauer, D., Morales, D.L.

“…As the field of heart transplantation (HTx) has undergone much growth over the last several years, it is essential that healthcare systems are able to…”
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Geranylgeranyl diphosphate synthase inhibitor and proteasome inhibitor combination therapy in multiple myeloma by Haney, Staci L, Varney, Michelle L, Williams, Jacob T, Smith, Lynette M, Talmon, Geoffrey, Holstein, Sarah A

“…Multiple myeloma (MM) remains an incurable malignancy, despite the advent of therapies such as proteosome inhibitors (PIs) that disrupt protein homeostasis and…”
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Introduction: Gender, Welfare, and States of Punishment by Haney, Lynne

“…This article provides both an introduction to this special section and a substantive analysis of convergence in the welfare and penal systems in the…”
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Flush of Carbon Dioxide Following Rewetting of Dried Soil Relates to Active Organic Pools by Franzluebbers, A. J., Haney, R. L., Honeycutt, C. W., Schomberg, H. H., Hons, F. M.

“…Soil quality assessment could become more standardized with the development of a simple, rapid, and reliable method for quantifying potential soil biological…”
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Corn response to selected soil health indicators in a Texas drought by Adhikari, Kabindra, Smith, Douglas R., Collins, Harold, Haney, Richard L., Wolfe, June E.

“…•Soil health indicators of Texas Blackland Soils were quantified.•Relationship between soil health and corn yield was modeled.•Field-scale variability of soil…”
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Relaxin regulates vascular wall remodeling and passive mechanical properties in mice by DEBRAH, Dan O, DEBRAH, Julianna E, HANEY, Jamie L, MCGUANE, Jonathan T, SACKS, Michael S, CONRAD, Kirk P, SHROFF, Sanjeev G

“…Administration of recombinant human relaxin (rhRLX) to conscious rats increases global arterial compliance, and small renal arteries (SRA) isolated from these…”
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The Peptide–Drug Conjugate Melflufen Modulates the Unfolded Protein Response of Multiple Myeloma and Amyloidogenic Plasma Cells and Induces Cell Death by Flanagan, Ken, Kumari, Romika, Miettinen, Juho J., Haney, Staci L., Varney, Michelle L., Williams, Jacob T., Majumder, Muntasir M., Suvela, Minna, Slipicevic, Ana, Lehmann, Fredrik, Nupponen, Nina N., Holstein, Sarah A., Heckman, Caroline A.

“…Immunoglobulin light‐chain (AL) amyloidosis is a rare disease caused by clonal plasma cell secretion of misfolded light chains that assemble as toxic amyloid…”
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