Search Results - "Handy, R D"

Antibacterial activity and biofilm inhibition by surface modified titanium alloy medical implants following application of silver, titanium dioxide and hydroxyapatite nanocoatings by Besinis, A., Hadi, S. D., Le, H. R., Tredwin, C., Handy, R. D.

“…One of the most common causes of implant failure is peri-implantitis, which is caused by bacterial biofilm formation on the surfaces of dental implants…”
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Sub-lethal effects of titanium dioxide nanoparticles on the physiology and reproduction of zebrafish by Ramsden, C.S., Henry, T.B., Handy, R.D.

“…► Effects of TiO2 NP, 0.1 or 1.0mgl−1; TiO2 bulk, 1.0mgl−1 exposure on zebrafish. ► 21-d post exposure recovery period tested TiO2 effects on reproductive…”
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Dose-dependent inorganic mercury absorption by isolated perfused intestine of rainbow trout, Oncorhynchus mykiss, involves both amiloride-sensitive and energy-dependent pathways by Hoyle, I., Handy, R.D.

“…The trophic transfer and nutritional toxicity of mercury (Hg) in aquatic food chains is well known, but there is limited information on the mechanism of…”
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Tissue Injury and Cellular Immune Responses to Cadmium Chloride Exposure in the Common Mussel Mytilus edulis: Modulation by Lipopolysaccharide by Sheir, S. K, Handy, R. D

“…The immunotoxic effects of cadmium (Cd) exposure in bivalves are poorly understood and whether or not stimulation of the immune system exacerbates Cd toxicity…”
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Dietary copper exposure in the African walking catfish, Clarias gariepinus: Transient osmoregulatory disturbances and oxidative stress by Hoyle, I., Shaw, B.J., Handy, R.D.

“…There are few dietary Copper (Cu) toxicity studies on warm water fish. We used the African walking catfish ( Clarias gariepinus) to perform the first in vivo…”
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Physiological modulation of iron metabolism in rainbow trout (Oncorhynchus mykiss) fed low and high iron diets by Carriquiriborde, P, Handy, R D, Davies, S J

“…Iron (Fe) is an essential element, but Fe metabolism is poorly described in fish and the role of ferrireductase and transferrin in iron regulation by teleosts…”
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The effects of dietary iron concentration on gastrointestinal and branchial assimilation of both iron and cadmium in zebrafish ( Danio rerio) by Cooper, C.A., Handy, R.D., Bury, N.R.

“…Zebrafish ( Danio rerio) were fed either a diet containing 33 mg Fe kg −1 (low) or 95 mg Fe kg −1 (normal) for 10 weeks, after which short-term Cd and Fe…”
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Sodium-sensitive and -insensitive copper accumulation by isolated intestinal cells of rainbow trout Oncorhynchus mykiss by Burke, J, Handy, R D

“…The pathway for copper (Cu) uptake across the mucosal membrane into intestinal cells has not been elucidated in fish. Copper accumulation in freshly isolated…”
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Are Biobased Microfibers Less Harmful than Conventional Plastic Microfibers: Evidence from Earthworms by Courtene-Jones, W., De Falco, F., Burgevin, F., Handy, R. D., Thompson, R. C.

“…Biobased plastics are sometimes promoted as “environmentally friendly” compared to their conventional petrochemical-based counterparts, but their ecotoxicity…”
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Chronic diazinon exposure: pathologies of spleen, thymus, blood cells, and lymph nodes are modulated by dietary protein or lipid in the mouse by Handy, R.D., Abd-El Samei, H.A., Bayomy, M.F.F., Mahran, A.M., Abdeen, A.M., El-Elaimy, E.A.

“…Little is known about the immunotoxicity of the organophosphate pesticide, diazinon. This study aims at detailing the pathologies in the thymus, spleen, blood…”
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Sodium-dependent copper uptake across epithelia: a review of rationale with experimental evidence from gill and intestine by Handy, R.D, Eddy, F.B, Baines, H

“…The paper reviews the evidence for apparent sodium-dependent copper (Cu) uptake across epithelia such as frog skin, fish gills and vertebrate intestine…”
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The minimum inhibitory concentration (MIC) assay with Escherichia coli: An early tier in the environmental hazard assessment of nanomaterials? by Vassallo, J., Besinis, A., Boden, R., Handy, R.D.

“…There are now over a thousand nano-containing products on the market and the antibacterial properties of some nanomaterials has created interest in their use…”
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Metabolic trade-off between locomotion and detoxification for maintenance of blood chemistry and growth parameters by rainbow trout ( Oncorhynchus mykiss) during chronic dietary exposure to copper by Handy, R.D, Sims, D.W, Giles, A, Campbell, H.A, Musonda, M.M

“…The aim of this study was to obtain a holistic view of the sublethal toxic responses, and compensations, of fish exposed to Cu in the diet. Rainbow trout were…”
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Graphene oxide biopolymer aerogels for the removal of lead from drinking water using a novel nano-enhanced ion exchange cascade by Bloor, J.M., Handy, R.D., Awan, S.A., Jenkins, D.F.L.

“…Potable water in developing countries often contains levels of toxic metals that exceed the recommended international limits, with impacts on human health. The…”
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Deterioration of bio-based polylactic acid plastic teabags under environmental conditions and their associated effects on earthworms by Courtene-Jones, W., Burgevin, F., Munns, L., Shillam, M.B.T., De Falco, F., Buchard, A., Handy, R.D., Thompson, R.C., Hanley, M.E.

“…In response to the plastic waste crisis, teabag producers have substituted the petrochemical-plastic content of their products with bio-based, biodegradable…”
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Toxic effects of nanoparticles and nanomaterials: Implications for public health, risk assessment and the public perception of nanotechnology by Handy, R. D., Shaw, B. J.

“…Nanomaterials are now being manufactured and used in many products. However, our knowledge of the human health effects and environmental concentrations of…”
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Physiological Responses: Their Measurement and Use as Environmental Biomarkers in Ecotoxicology by Handy, R D, Depledge, M H

“…This paper briefly reviews the utility of physiological measurements as biomarkers of pollutant exposure and biological effect, and then gives a step by step…”
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Shifts in a Fish’s Resource Holding Power during a Contact Paired Interaction: The Influence of a Copper‐Contaminated Diet in Rainbow Trout by Campbell, H. A., Handy, R. D., Sims, D. W.

“…The influence of sublethal chronic dietary copper (Cu) exposure on the dominant‐subordinate relationship between pairs of juvenile rainbow trout (Oncorhynchus…”
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Stress proteins (HSP's): Methods of Detection and Their Use as an Environmental Biomarker by Lewis, S, Handy, R D, Cordi, B, Billinghurst, Z, Depledge, M H

“…This paper briefly reviews the nomenclature and application of stress proteins as biomarkers, then gives a step by step description of the popular…”
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Mechanisms of gastrointestinal copper absorption in the African walking catfish: copper dose-effects and a novel anion-dependent pathway in the intestine by Handy, R D, Musonda, M M, Phillips, C, Falla, S J

“…In mammals, copper (Cu) absorption occurs mostly in the small intestine, and some of the Cu transporters involved in its uptake have been characterised. In…”
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