Search Results - "Handrock, R"
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Efficacy and safety of valsartan 160/HCTZ 25 mg in fixed combination in hypertensive patients not controlled by candesartan 32 mg plus HCTZ 25 mg in free combination
Published in Current medical research and opinion (01-11-2007)“…ABSTRACT Objective: Free combination hypertension medication is associated with a lower compliance and less persistence compared to fixed combination therapy…”
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The role of nitric oxide in the regulation of glomerular haemodynamics in humans
Published in Nephrology, dialysis, transplantation (01-06-2004)“…Background. According to experimental data, the afferent glomerular arteriole is particularly under control of nitric oxide (NO). By use of pharmacological…”
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Efficacy and safety of the single pill combination of amlodipine 10 mg plus valsartan 160 mg in hypertensive patients not controlled by amlodipine 10 mg plus olmesartan 20 mg in free combination
Published in Current medical research and opinion (01-02-2009)“…ABSTRACT Background and objective: For patients with moderate hypertension (grade 2, defined as systolic blood pressure [SBP] 160-179 mmHg and/or diastolic…”
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Efficacy, safety and tolerability of valsartan 80 mg compared to irbesartan 150 mg in hypertensive patients on long-term hemodialysis (VALID study)
Published in Clinical nephrology (01-06-2008)“…End stage renal disease (ESRD) patients mainly die of cardiovascular disease, and hypertension is regarded as the major risk factor. Valsartan is an…”
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Combination of amlodipine 10 mg and valsartan 160 mg lowers blood pressure in patients with hypertension not controlled by an ACE inhibitor/CCB combination
Published in Blood pressure. Supplement (2008)“…This multicenter, open-label, single-arm trial assessed the efficacy of the combination of amlodipine 10 mg and valsartan 160 mg to provide additional blood…”
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New fluorine-containing hypotensive preparations
Published in Journal of fluorine chemistry (01-06-2001)“…The synthesis and pharmacological properties of a novel type of vasorelaxant hybrid compounds are described. The investigated compounds are based on…”
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Interaction of three structurally distinct Ca2+ channel activators with single L-type Ca2+ channels
Published in Naunyn-Schmiedeberg's archives of pharmacology (01-08-1999)“…The dihydropyridine S(-)-Bay K 8644 (Bay K), the benzoylpyrrole FPL 64176 (FPL) and the benzodiazocine CGP 48506 (CGP) are structurally unrelated L-type Ca2+…”
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Antihypertensive effects of valsartan/hydrochlorothiazide combination in essential hypertension
Published in Blood pressure (2001)“…Fixed-dose combination therapy has received increased interest since publication of JNC-VI report and WHO/ISH guidelines 1999. We compared in a randomized,…”
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Effect of AT receptor blockade on endothelial function in essential hypertension
Published in American journal of hypertension (01-02-2003)Get full text
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Increased availability and open probability of single L-type calcium channels from failing compared with nonfailing human ventricle
Published in Circulation (New York, N.Y.) (08-09-1998)“…The role of the L-type calcium channel in human heart failure is unclear, on the basis of previous whole-cell recordings. We investigated the properties of…”
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Prognostic Value of the QRS Duration in Patients With Heart Failure: A Subgroup Analysis From 24 Centers of Val-HeFT
Published in Journal of cardiac failure (01-09-2005)“…This study investigated whether QRS duration (QRS D) is a prognostic indicator in patients with heart failure (New York Heart Association [NYHA] classes…”
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Effects of selective angiotensin II receptor blockade on sympathetic nerve activity in primary hypertensive subjects
Published in Journal of hypertension (01-06-2002)“…OBJECTIVE The role of the renin–angiotensin system in the regulation of sympathetic nervous activity in human hypertension was evaluated in patients with…”
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Direct comparison of the effects of valsartan and amlodipine on renal hemodynamics in human essential hypertension
Published in American journal of hypertension (01-12-2003)“…To elucidate the renoprotective mechanism of AT 1-receptor blockers, we compared the effects of the AT 1-receptor blocker valsartan with those of the calcium…”
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THE EFFECT OF VALSARTAN ON THE ENDOTHELIAL FUNCTION OF THE RETINAL CAPILLARY BED: 4D.2
Published in Journal of hypertension (01-06-2004)Get full text
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EFFECTS OF VALSARTAN AND METOPROLOL ON LARGE ARTERY FUNCTION IN HYPERTENSIVE PATIENTS: OP 108
Published in Journal of hypertension (01-02-2004)Get full text
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Ca2+-dependent modulation of single human cardiac L-type calcium channels by the calcineurin inhibitor cyclosporine
Published in Journal of molecular and cellular cardiology (01-02-2004)“…Activity of single L-type calcium channels (LTCC) is enhanced in human failing myocardium (Circulation 98 (1998) 969.), most likely due to impaired…”
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Single-channel pharmacology of mibefradil in human native T-type and recombinant Ca(v)3.2 calcium channels
Published in Molecular pharmacology (01-03-2002)“…To study the molecular pharmacology of low-voltage-activated calcium channels in biophysical detail, human medullary thyroid carcinoma (hMTC) cells were…”
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VALSARTAN 160/HCTZ 25 EFFECTIVELY REDUCES BLOOD PRESSURE IN HYPERTENSIVE PATIENTS NOT CONTROLLED BY VALSARTAN 160/HCTZ 12.5: P3.358
Published in Journal of hypertension (01-06-2004)Get full text
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Single-channel properties of L-type calcium channels from failing human ventricle
Published in Cardiovascular research (01-02-1998)“…The aim of our study was to analyse the single-channel properties of L-type calcium channels from failing human heart and to compare them to the respective…”
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