Search Results - "Handler, Chenchen"

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  1. 1

    Time-lapse mechanical imaging of neural tube closure in live embryo using Brillouin microscopy by Handler, Chenchen, Scarcelli, Giuliano, Zhang, Jitao

    Published in Scientific reports (06-01-2023)
    “…Neural tube closure (NTC) is a complex process of embryonic development involving molecular, cellular, and biomechanical mechanisms. While the genetic factors…”
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    Journal Article
  2. 2

    P300 Modulates Endothelial Mechanotransduction of Fluid Shear Stress by Whitworth, Chloe P., Aw, Wen Y., Doherty, Elizabeth L., Handler, Chenchen, Ambekar, Yogeshwari, Sawhney, Aanya, Scarcelli, Giuliano, Polacheck, William J.

    Published in Cellular and molecular bioengineering (01-10-2024)
    “…Purpose P300 is a lysine acetyltransferase that plays a significant role in regulating transcription and the nuclear acetylome. While P300 has been shown to be…”
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    Journal Article
  3. 3

    Advantages of integrating Brillouin microscopy in multimodal mechanical mapping of cells and tissues by Handler, Chenchen, Testi, Claudia, Scarcelli, Giuliano

    Published in Current opinion in cell biology (01-06-2024)
    “…Recent research has highlighted the growing significance of the mechanical properties of cells and tissues in the proper execution of physiological functions…”
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    Journal Article
  4. 4

    Monitoring the Mechanical Evolution of Tissue During Neural Tube Closure of Chick Embryo by Shi, Chenjun, Handler, Chenchen, Florn, Haden, Zhang, Jitao

    Published in Journal of visualized experiments (10-11-2023)
    “…Neural tube closure (NTC) is a critical process during embryonic development. Failure in this process can lead to neural tube defects, causing congenital…”
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    Journal Article
  5. 5

    Mechanical Mapping of Neural Tube Closure in Live Embryos Using Brillouin Microscopy by Handler, Chenchen

    Published 01-01-2022
    “…Neurulation is a process that serves as the precursor to the spinal cord in vertebrates. Neural tube closure (NTC), part of primary neurulation, involves the…”
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    Dissertation
  6. 6

    TIMP-2 suppresses tumor growth and metastasis in murine model of triple-negative breast cancer by Peeney, David, Jensen, Sandra M, Castro, Nadia P, Kumar, Sarvesh, Noonan, Silvia, Handler, Chenchen, Kuznetsov, Alex, Shih, Joanna, Tran, Andy D, Salomon, David S, Stetler-Stevenson, William G

    Published in Carcinogenesis (New York) (14-05-2020)
    “…Abstract Metastasis is the primary cause of treatment failures and mortality in most cancers. Triple-negative breast cancer (TNBC) is refractory to treatment…”
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    Journal Article
  7. 7

    Stimulated Brillouin scattering flow cytometry by Rosvold, Jake R, Zanini, Giulia, Handler, Chenchen, Frank, Eric, Li, Jiarui, Vitolo, Michele I, Martin, Stuart S, Scarcelli, Giuliano

    Published in Biomedical optics express (01-10-2024)
    “…We present the use of stimulated Brillouin scattering spectroscopy to achieve rapid measurements of cell biomechanics in a flow cytometer setup. Specifically,…”
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    Journal Article