Search Results - "Handke, Wiebke"
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Inactivation of three emerging viruses – severe acute respiratory syndrome coronavirus, Crimean–Congo haemorrhagic fever virus and Nipah virus – in platelet concentrates by ultraviolet C light and in plasma by methylene blue plus visible light
Published in Vox sanguinis (01-04-2020)“…Background Emerging viruses like severe acute respiratory syndrome coronavirus (SARS‐CoV), Crimean–Congo haemorrhagic fever virus (CCHFV) and Nipah virus (NiV)…”
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Calcium spirulan derived from Spirulina platensis inhibits herpes simplex virus 1 attachment to human keratinocytes and protects against herpes labialis
Published in Journal of allergy and clinical immunology (01-01-2016)“…Background Chronic infections with herpes simplex virus (HSV) type 1 are highly prevalent in populations worldwide and cause recurrent oral lesions in up to…”
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Novel method for determining when a field‐collected donor unit is sufficiently full
Published in Transfusion (Philadelphia, Pa.) (01-05-2024)“…Background Whole blood (WB) collections can occur downrange for immediate administration. An important aspect of these collections is determining when the unit…”
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Comparative Analysis of Mesenchymal Stem Cell Cultivation in Fetal Calf Serum, Human Serum, and Platelet Lysate in 2D and 3D Systems
Published in Frontiers in bioengineering and biotechnology (15-01-2021)“…two-dimensional (2D) and three-dimensional (3D) cultivation of mammalian cells requires supplementation with serum. Mesenchymal stem cells (MSCs) are widely…”
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Gelatin-Methacryloyl (GelMA) Formulated with Human Platelet Lysate Supports Mesenchymal Stem Cell Proliferation and Differentiation and Enhances the Hydrogel's Mechanical Properties
Published in Bioengineering (Basel) (28-08-2019)“…Three-dimensional (3D) cell culture is a major focus of current research, since cultivation under physiological conditions provides more reliable information…”
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Live or let die: manipulation of cellular suicide programs by murine cytomegalovirus
Published in Medical microbiology and immunology (01-11-2012)“…Cytomegaloviruses (CMVs) are large double-stranded DNA viruses that replicate slowly and cause life-long persisting infections in their hosts. To achieve this,…”
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Timing of gamma irradiation and blood donor sex influences in vitro characteristics of red blood cells
Published in Transfusion (Philadelphia, Pa.) (01-04-2018)“…BACKGROUND There are few studies investigating the effect of irradiation on red blood cells (RBCs) during storage. This study analyzed changes in in vitro…”
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Recommendations for in vitro evaluation of blood components collected, prepared and stored in non‐DEHP medical devices
Published in Vox sanguinis (01-02-2023)“…Background and Objectives DEHP, di(2‐ethylhexyl) phthalate, is the most common member of the class of ortho‐phthalates, which are used as plasticizers. The…”
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Mutations in the M112/M113-Coding Region Facilitate Murine Cytomegalovirus Replication in Human Cells
Published in Journal of Virology (01-08-2010)“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Xeno-Free In Vitro Cultivation and Osteogenic Differentiation of hAD-MSCs on Resorbable 3D Printed RESOMER
Published in Materials (31-07-2020)“…The development of alloplastic resorbable materials can revolutionize the field of implantation technology in regenerative medicine. Additional opportunities…”
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Viral Inhibition of BAK Promotes Murine Cytomegalovirus Dissemination to Salivary Glands
Published in Journal of Virology (01-03-2013)“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Inactivation of Ebola virus and Middle East respiratory syndrome coronavirus in platelet concentrates and plasma by ultraviolet C light and methylene blue plus visible light, respectively
Published in Transfusion (Philadelphia, Pa.) (01-09-2018)“…BACKGROUND Ebola virus (EBOV) and Middle East respiratory syndrome coronavirus (MERS‐CoV) have been identified as potential threats to blood safety. This study…”
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Bacterial inactivation of platelet concentrates with the THERAFLEX UV‐Platelets pathogen inactivation system
Published in Transfusion (Philadelphia, Pa.) (01-04-2019)“…BACKGROUND The THERAFLEX UV‐Platelets system (Maco Pharma) uses ultraviolet C (UVC) light for pathogen inactivation (PI) of platelet concentrates (PCs) without…”
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Dose‐dependent inactivation of Plasmodium falciparum in red blood cell concentrates by treatment with short‐wavelength ultraviolet light
Published in Vox sanguinis (01-10-2024)“…Background and Objectives Plasmodium species are naturally transmitted by Anopheles mosquitos. The parasite infects red blood cells (RBCs) and can be…”
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Growth and Distribution of Bacteria in Contaminated Whole Blood and Derived Blood Components
Published in Transfusion medicine and hemotherapy (01-04-2024)“…Introduction: Bacterial contamination of blood products presumably occurs mainly during blood collection, starting from low initial concentrations of 10–100…”
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New ultraviolet C light‐based method for pathogen inactivation of red blood cell units
Published in Transfusion (Philadelphia, Pa.) (01-11-2022)“…Background Pathogen inactivation (PI) technologies for platelet concentrates and plasma are steadily becoming more established, but new PI treatment options…”
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Digital droplet polymerase chain reaction to monitor ultravioletC treatment of single‐donor and buffy coat platelet units
Published in Transfusion (Philadelphia, Pa.) (01-08-2020)“…BACKGROUNDUVC illumination of agitated platelet concentrates (PCs) inactivates pathogens and white blood cells by modifications of their nucleic acids. Related…”
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Journal Article -
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Digital droplet polymerase chain reaction to monitor ultraviolet C treatment of single‐donor and buffy coat platelet units
Published in Transfusion (Philadelphia, Pa.) (01-08-2020)“…BACKGROUND UVC illumination of agitated platelet concentrates (PCs) inactivates pathogens and white blood cells by modifications of their nucleic acids…”
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Hepatitis E virus is effectively inactivated in platelet concentrates by ultraviolet C light
Published in Vox sanguinis (01-10-2020)“…Background and Objectives As previous investigations have shown, THERAFLEX UV‐Platelets, a UVC‐based pathogen inactivation (PI) system, is effective against…”
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Journal Article -
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Mitochondrial DNA multiplex real‐time polymerase chain reaction inhibition assay for quality control of pathogen inactivation by ultraviolet C light in platelet concentrates
Published in Transfusion (Philadelphia, Pa.) (01-03-2018)“…BACKGROUND Several ultraviolet (UV) light‐based pathogen inactivation (PI) technologies for platelet (PLT) products have been developed or are under…”
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