Search Results - "Hand, Tracey"
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Prostaglandin D2 mediates neuronal protection via the DP1 receptor
Published in Journal of neurochemistry (01-02-2005)“…Cyclo‐oxygenases (COXs) catalyze the first committed step in the synthesis of the prostaglandins PGE2, PGD2, PGF2α, PGI2 and thomboxane A2. Expression and…”
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2
Filaggrin mutations that confer risk of atopic dermatitis confer greater risk for eczema herpeticum
Published in Journal of allergy and clinical immunology (01-09-2009)“…Background Loss-of-function null mutations R501X and 2282del4 in the skin barrier gene, filaggrin ( FLG ), represent the most replicated genetic risk factors…”
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3
Genetic variants in thymic stromal lymphopoietin are associated with atopic dermatitis and eczema herpeticum
Published in Journal of allergy and clinical immunology (01-06-2010)“…Quality controls were performed as described previously.6 The Cochran-Armitage trend test was used to test for association between each SNP and disease status…”
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4
FADS genetic variants and ω-6 polyunsaturated fatty acid metabolism in a homogeneous island population[S]
Published in Journal of lipid research (01-09-2010)“…Long-chain polyunsaturated fatty acids (PUFA) orchestrate immunity and inflammation through their capacity to be converted to potent inflammatory mediators. We…”
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5
Neuronal overexpression of cyclooxygenase-2 increases cerebral infarction
Published in Annals of neurology (01-08-2003)“…Increases in COX‐2 enzymatic activity and prostaglandin production have been associated with neuronal injury in both acute and age‐related degenerative…”
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6
Essential Features of the Catalytic Core of Peptidyl-α-hydroxyglycine α-Amidating Lyase
Published in Biochemistry (Easton) (15-10-2002)“…Bioactive peptides frequently terminate with an essential α-amide that is generated from a COOH-terminal Gly in a two-step enzymatic process occurring within…”
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7
Best practice recommendations for the measurement and interpretation of salivary proinflammatory cytokines in biobehavioral research
Published in Brain, behavior, and immunity (01-01-2021)“…•Salivary IL-1β, IL-6, IL-8, and TNF-α were measured in healthy adults.•Cytokine changes were assessed across a series of saliva collection and handling…”
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8
Neuroprotective function of the PGE2 EP2 receptor in cerebral ischemia
Published in The Journal of neuroscience (07-01-2004)“…The cyclooxygenases COX-1 and COX-2 catalyze the first committed step of prostaglandin synthesis from arachidonic acid. Previous studies in rodent stroke…”
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9
Kalirin Inhibition of Inducible Nitric-oxide Synthase
Published in The Journal of biological chemistry (08-01-1999)“…Nitric oxide (NO) acts as a neurotransmitter. However, excess NO produced from neuronal NO synthase (nNOS) or inducible NOS (iNOS) during inflammation of the…”
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10
Deletion of the Prostaglandin E2 EP2 Receptor Reduces Oxidative Damage and Amyloid Burden in a Model of Alzheimer's Disease
Published in The Journal of neuroscience (02-11-2005)“…Epidemiological studies demonstrate that chronic use of nonsteroidal anti-inflammatory drugs (NSAIDs) in normal aging populations reduces the risk of…”
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11
Adiponectin: Serum-saliva associations and relations with oral and systemic markers of inflammation
Published in Peptides (New York, N.Y. : 1980) (01-05-2017)“…•Salivary adiponectin was positively correlated with salivary inflammatory activity.•Salivary and serum adiponectin were not related to serum inflammatory…”
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12
Breeding Stock-Specific Variation in Peptidylglycineα -Amidating Monooxygenase Messenger Ribonucleic Acid Splicing in Rat Pituitary1
Published in Endocrinology (Philadelphia) (01-02-2000)“…Peptidylglycine α-amidating monooxygenase (PAM) is a bifunctional enzyme that catalyzes the carboxyl-terminal amidation of glycine-extended peptides in a…”
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13
Deletion of the Prostaglandin E 2 EP2 Receptor Reduces Oxidative Damage and Amyloid Burden in a Model of Alzheimer's Disease
Published in The Journal of neuroscience (02-11-2005)“…Epidemiological studies demonstrate that chronic use of nonsteroidal anti-inflammatory drugs (NSAIDs) in normal aging populations reduces the risk of…”
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14
Prostaglandin D 2 mediates neuronal protection via the DP1 receptor
Published in Journal of neurochemistry (01-02-2005)“…Cyclo‐oxygenases (COXs) catalyze the first committed step in the synthesis of the prostaglandins PGE 2 , PGD 2 , PGF 2α , PGI 2 and thomboxane A 2 . Expression…”
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Journal Article -
15
Kalirin, a Multifunctional PAM COOH-terminal Domain Interactor Protein, Affects Cytoskeletal Organization and ACTH Secretion from AtT-20 Cells
Published in The Journal of biological chemistry (29-01-1999)“…The production and regulated secretion of bioactive peptides require a series of lumenal enzymes to convert inactive precursors into bioactive peptides plus…”
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16
A genome-wide association study on African-ancestry populations for asthma
Published in Journal of allergy and clinical immunology (01-02-2010)“…Background Asthma is a complex disease characterized by striking ethnic disparities not explained entirely by environmental, social, cultural, or economic…”
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17
Genetic Variants in Interferon Regulatory Factor 2 (IRF2) Are Associated with Atopic Dermatitis and Eczema Herpeticum
Published in Journal of investigative dermatology (01-03-2012)“…Interferon regulatory factor 2 (IRF2) is a member of a family of transcriptional factors involved in the modulation of IFN-induced immune responses to viral…”
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18
African ancestry is associated with risk of asthma and high total serum IgE in a population from the Caribbean Coast of Colombia
Published in Human genetics (01-06-2009)“…African descended populations exhibit an increased prevalence of asthma and allergies compared to Europeans. One approach to distinguish between environmental…”
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Gene Encoding Duffy Antigen/Receptor for Chemokines Is Associated with Asthma and IgE in Three Populations
Published in American journal of respiratory and critical care medicine (15-11-2008)“…Asthma prevalence and severity are high among underserved minorities, including those of African descent. The Duffy antigen/receptor for chemokines is the…”
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20
Personalizing death in the intensive care unit: the 3 Wishes Project: a mixed-methods study
Published in Annals of internal medicine (18-08-2015)“…Dying in the complex, efficiency-driven environment of the intensive care unit can be dehumanizing for the patient and have profound, long-lasting consequences…”
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