Search Results - "Hancock, Gerald E"

Matrix metalloproteinase-9 and tissue inhibitor of matrix metalloproteinase-1 in the respiratory tracts of human infants following paramyxovirus infection by Elliott, Matthew B., Welliver Sr, Robert C., Laughlin, Todd S., Pryharski, Karin S., LaPierre, Natisha A., Chen, Tong, Souza, Victor, Terio, Nicole B., Hancock, Gerald E.

“…Respiratory syncytial (RSV) and parainfluenza (PIV) viruses are primary causes of acute bronchiolitis and wheezing illnesses in infants and young children. To…”
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Characterization of Recombinant Respiratory Syncytial Viruses with the Region Responsible for Type 2 T-Cell Responses and Pulmonary Eosinophilia Deleted from the Attachment (G) Protein by ELLIOTT, Matthew B, PRYHARSKI, Karin S, LAPIERRE, Natisha A, HEERS DACK, Kristen M, HANCOCK, Gerald E, QINGZHONG YU, BOUTILIER, L. A, CAMPEOL, N, MELVILLE, K, LAUGHLIN, Todd S, GUPTA, C. K, LERCH, Robert A, RANDOLPH, Valerie B

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Recombinant Respiratory Syncytial Viruses Lacking the C-Terminal Third of the Attachment (G) Protein Are Immunogenic and Attenuated In Vivo and In Vitro by ELLIOTT, Matthew B, PRYHARSKI, Karin S, HANCOCK, Gerald E, QINGZHONG YU, PARKS, Christopher L, LAUGHLIN, Todd S, KANTA GUPTA, C, LERCH, Robert A, RANDOLPH, Valerie B, LAPIERRE, Natisha A, DACK, Kristen M

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Adaptive Immune Responses of Patients with Asthma to the Attachment (G) Glycoprotein of Respiratory Syncytial Virus by Hancock, Gerald E., Scheuer, Catherine A., Sierzega, Renata, Pryharski, Karin S., McBride, John T., Miller Watelet, Luc F., Tebbey, Paul W., Smith, Jason D.

“…A history of acute bronchiolitis in infancy caused by respiratory syncytial virus is a risk factor for recurrent wheezing in early childhood. Because the…”
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Atypical pulmonary eosinophilia is mediated by a specific amino acid sequence of the attachment (G) protein of respiratory syncytial virus by Tebbey, P W, Hagen, M, Hancock, G E

“…We analyzed the immune responses evoked by a series of overlapping peptides to better understand the molecular basis for respiratory syncytial virus (RSV) G…”
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Alphavirus replicon particles encoding the fusion or attachment glycoproteins of respiratory syncytial virus elicit protective immune responses in BALB/c mice and functional serum antibodies in rhesus macaques by Elliott, Matthew B, Chen, Tong, Terio, Nicole B, Chong, Siew-Yen, Abdullah, Rashed, Luckay, Amara, Egan, Michael A, Boutilier, Lee Anne, Melville, Krista, Lerch, Robert A, Long, Deborah, Eldridge, John. H, Parks, Christopher L, Udem, Stephen A, Hancock, Gerald E

“…Abstract Respiratory syncytial virus (RSV) is a major cause of acute respiratory tract disease in humans. Towards development of a prophylactic vaccine, we…”
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B-cell depletion inhibits arthritis in a collagen-induced arthritis (CIA) model, but does not adversely affect humoral responses in a respiratory syncytial virus (RSV) vaccination model by Dunussi-Joannopoulos, Kyri, Hancock, Gerald E., Kunz, Arthur, Hegen, Martin, Zhou, Xiaochuan X., Sheppard, Barbara J., Lamothe, Jennifer, Li, Evelyn, Ma, Hak-Ling, Hamann, Philip R., Damle, Nitin K., Collins, Mary

“…We report the development of a mouse B cell-depleting immunoconjugate (anti-CD22 monoclonal antibody [mAb] conjugated to calicheamicin) and its in vivo use to…”
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Adjuvants recognized by toll-like receptors inhibit the induction of polarized type 2 T cell responses by natural attachment (G) protein of respiratory syncytial virus by Hancock, Gerald E., Heers, Kristen M., Pryharski, Karin S., Smith, Jason D., Tiberio, Lorrie

“…Immunization with native fusion (F) protein from respiratory syncytial virus (RSV) adsorbed to alum adjuvant generates greater than fourfold rises in serum…”
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Inhibition of respiratory syncytial virus infection with the CC chemokine RANTES (CCL5) by Elliott, Matthew B., Tebbey, Paul W., Pryharski, Karin S., Scheuer, Catherine A., Laughlin, Todd S., Hancock, Gerald E.

“…Respiratory syncytial virus (RSV) is a major cause of respiratory tract disease in infants, aged adults, and immunosuppressed patients. The only approved…”
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CpG containing oligodeoxynucleotides are potent adjuvants for parenteral vaccination with the fusion (F) protein of respiratory syncytial virus (RSV) by Hancock, Gerald E, Heers, Kristen M, Smith, Jason D, Scheuer, Catherine A, Ibraghimov, Alexander R, Pryharski, Karin S

“…The feasibility of using oligodeoxynucleotides (ODN) containing unmethylated CpG motifs as parenteral adjuvants for subunit vaccines against RSV was tested in…”
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Immune responses to the nonglycosylated ectodomain of respiratory syncytial virus attachment glycoprotein mediate pulmonary eosinophilia in inbred strains of mice with different MHC haplotypes by Hancock, Gerald E., Tebbey, Paul W., Scheuer, Catherine A., Pryharski, Karin S., Heers, Kristen M., LaPierre, Natisha A.

“…Development of subunit vaccines against respiratory syncytial virus (RSV) for naive human infants is hindered by concerns that immunization with the fusion or…”
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Effective mucosal immunization against respiratory syncytial virus using purified F protein and a genetically detoxified cholera holotoxin, CT-E29H by Tebbey, Paul W, Scheuer, Catherine A, Peek, Joel A, Zhu, Duzhang, LaPierre, Natisha A, Green, Bruce A, Phillips, Eric D, Ibraghimov, Alexander R, Eldridge, John H, Hancock, Gerald E

“…We exploited the powerful adjuvant properties of cholera holotoxin (CT) to create a mucosally administered subunit vaccine against respiratory syncytial virus…”
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Serum Neutralizing Antibody Titers of Seropositive Chimpanzees Immunized with Vaccines Coformulated with Natural Fusion and Attachment Proteins of Respiratory Syncytial Virus by Hancock, Gerald E., Smith, Jason D., Heers, Kristen M.

“…Subunit vaccines formulated with purified fusion proteins from the A2 (PFP-2) or attenuated 248/404 (PFP-3) strains of respiratory syncytial virus (RSV) were…”
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Generation of atypical pulmonary inflammatory responses in BALB/c mice after immunization with the native attachment (G) glycoprotein of respiratory syncytial virus by Hancock, G E, Speelman, D J, Heers, K, Bortell, E, Smith, J, Cosco, C

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B-cell depletion inhibits arthritis in a collagen-induced arthritis (CIA) model, but does not adversely affect humoral responses in a respiratory syncytial virus (RSV) vaccination model. Commentary by DUNUSSI-JOANNOPOULOS, Kyri, HANCOCK, Gerald E, DAMLE, Nitin K, COLLINS, Mary, HIEPE, Falk, RADBRUCH, Andreas, KUNZ, Arthur, HEGEN, Martin, ZHOU, Xiaochuan X, SHEPPARD, Barbara J, LAMOTHE, Jennifer, LI, Evelyn, MA, Hak-Ling, HAMANN, Philip R

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Serum neutralizing antibody titers of seropositive chimpanzees immunized with vaccines coformulated with natural fusion and attachment proteins of respiratory by Hancock, Gerald E, Smith, Jason D, Heers, Kristen M

“…Subunit vaccines formulated with purified fusion proteins from the A2 (PFP-2) or attenuated 248/404 (PFP-3) strains of respiratory syncytial virus (RSV) were…”
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Adaptive immune reponse of patients with asthma to the attachment (G) glycoprotein of respiratory syncytial virus by Hancock, Gerald E, Scheuer, Catherine A, Sierzega, Renata, Pryharski, Karin S

“…A history of acute bronchiolitis in infancy caused by respiratory syncytial virus is a risk factor for recurrent wheezing in early childhood. Because the…”
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The attachment (G) glycoprotein of respiratory syncytial virus (RSV) enhances IL-3-mediated IL-13 production by human basophils by Schroeder, John T, Bieneman, Anja, Sin, Aytul Z, Kim, Hyun-Hee, Tebbey, Paul W, Hancock, Gerald E

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Formulation of the purified fusion protein of respiratory syncytial virus with the saponin QS-21 induces protective immune responses in Balb/c mice that are similar to those generated by experimental infection by HANCOCK, G. E, SPEELMAN, D. J, FRENCHICK, P. J, MINEO-KUHN, M. M, BAGGS, R. B, HAHN, D. J

“…The feasibility of employing a vaccine composed of the purified fraction 21 of Quillaja saponaria (QS-21) and the fusion (F) protein of respiratory syncytial…”
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Keratinocyte growth regulation by the products of immune cells by HANCOCK, G. E, KAPLAN, G, COHN, Z. A

“…We describe a bioassay that allows the in vitro investigation of the stimulatory and suppressive factors derived from immune cells in short-term cultures of…”
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