Search Results - "Hance, Michael"
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Secreted Hsp90 Is a Novel Regulator of the Epithelial to Mesenchymal Transition (EMT) in Prostate Cancer
Published in The Journal of biological chemistry (02-11-2012)“…Prostate cancer (PCa) is the most frequently diagnosed malignancy in men, and the second highest contributor of male cancer related lethality. Disease…”
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Journal Article -
2
Tumor-secreted Hsp90 Subverts Polycomb Function to Drive Prostate Tumor Growth and Invasion
Published in The Journal of biological chemistry (27-03-2015)“…Prostate cancer remains the second highest contributor to male cancer-related lethality. The transition of a subset of tumors from indolent to invasive disease…”
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Journal Article -
3
The double-edged sword: conserved functions of extracellular hsp90 in wound healing and cancer
Published in Cancers (06-05-2014)“…Heat shock proteins (Hsps) represent a diverse group of chaperones that play a vital role in the protection of cells against numerous environmental stresses…”
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Comparative analysis of novel and conventional Hsp90 inhibitors on HIF activity and angiogenic potential in clear cell renal cell carcinoma: implications for clinical evaluation
Published in BMC cancer (15-12-2011)“…Perturbing Hsp90 chaperone function targets hypoxia inducible factor (HIF) function in a von Hippel-Lindau (VHL) independent manner, and represents an approach…”
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5
Effects of photo stimulation and nonstimulation of golden hamsters (Mesocricetus auratus) from birth to early puberty on testes structure and function
Published in Histology and histopathology (01-11-2009)“…We tested whether puberty in golden hamsters is photoperiodically controlled. Hamsters were raised under 14:10 hours Light:Dark (14L) and 1:23 hours Light:Dark…”
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Journal Article -
6
G-Protein Inwardly Rectifying Potassium Channel 1 (GIRK1) Knockdown Decreases Beta-Adrenergic, MAP Kinase and Akt Signaling in the MDA-MB-453 Breast Cancer Cell Line
Published in Breast cancer : basic and clinical research (01-01-2008)“…Previous data from our laboratory have indicated that there is a functional link between the beta-adrenergic receptor signaling pathway and the G-protein…”
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7
Abstract 1448: Dynamic chromatin modification by tumor secreted Hsp90 modulates EMT and tumor invasion
Published in Cancer research (Chicago, Ill.) (01-08-2015)“…Abstract Tumor metastasis is the main cause of prostate cancer lethality. Pathological reactivation of the developmental genetic program epithelial to…”
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Journal Article -
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Abstract 348: Extracellular heat shock protein 90 (eHsp90) initiates EMT events and enhances cell motility in prostate cancer
Published in Cancer research (Chicago, Ill.) (15-04-2012)“…Abstract Prostate Cancer (PCa) is the most commonly diagnosed malignancy in men, responsible for the second highest lethality. Although early cancer detection…”
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Journal Article -
9
G-Protein Inwardly Rectifying Potassium Channel 1 (GIRK1) Knockdown Decreases Beta-Adrenergic, MAP Kinase and Akt Signaling in the MDA-MB-453 Breast Cancer Cell Line
Published in Breast cancer : basic and clinical research (01-01-2008)“…Michael W. Hance1, Madhu S. Dhar2 and Howard K. Plummer III1 1Molecular Cancer Analysis Laboratory, Department of Pathobiology, College of Veterinary Medicine,…”
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Journal Article -
10
Advanced High-Strength Steel (AHSS) Performance Level Definitions and Targets
Published in SAE International journal of materials and manufacturing (03-04-2018)“…A novel performance classification system has been developed for advanced high-strength steel (AHSS). This system considers intrinsic global and local…”
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Journal Article -
11
Abstract A74: Tumor secreted Hsp90 initiates tumor growth and the epithelial to mesenchymal transition (EMT) in prostate cancer
Published in Cancer research (Chicago, Ill.) (01-02-2013)“…Abstract Prostate cancer (PCa) is the most frequently diagnosed malignancy and second most common cause of cancer related lethality in men. Disease mortality…”
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Journal Article -
12
Measurement of inclusive isolated prompt photon production at center of mass energy = 7 TeV with the ATLAS
Published 01-01-2011“…Prompt photons at hadron colliders are useful probes of perturbative quantum chromodynamics (pQCD), and are also found in signatures of new physics. A precise…”
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Dissertation -
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Abstract 545: Heat Shock Protein 90 (eHsp90): A novel modulator of the tumor microenvironment and cancer progression
Published in Cancer research (Chicago, Ill.) (15-04-2010)“…Abstract Prostate Cancer (PCa) is one of the most lethal diseases afflicting men. Although early cancer detection and treatment is often curative, subsequent…”
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Journal Article -
14
Characterizing Novel Indium Phosphide Pad Detectors with Focused X-ray Beams and Laboratory Tests
Published 29-05-2024“…Future tracking systems in High Energy Physics experiments will require large instrumented areas with low radiation length. Crystalline silicon sensors have…”
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Journal Article -
15
The influence of deformation-induced residual stresses on the post-forming tensile stress/strain behavior of dual -phase steels
Published 01-01-2005“…It was hypothesized that, in dual-phase (DP) steels, strain partitioning between ferrite (α) and martensite (α') during deformation results in a distribution…”
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Dissertation -
16
The influence of deformation-induced residual stresses on the post-forming tensile stress/strain behavior of dual-phase steels
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Dissertation